1,721,075 research outputs found
RECEPTOR-MEDIATED PATHWAYS OF ENDOTHELIUM ACTIVITY IN EXPERIMENTAL ATHEROSCLEROSIS
No full textThe pharmacological characterization of endothelial receptor activity during the progression of atherosclerosis in Watanabe heritable hyperlipidemic (WHHL) rabbits was examined. The data presented show that progression of atherosclerosis affects endothelial receptor functionality in different ways. Nucleotide receptor activity is preserved for longer than that of the other endothelial receptors, i.e. muscarinic- and P2y-purinoceptors. This difference means that, in WHHL rabbit aorta, some mechanisms proposed to explain impaired endothelium-mediated relaxation in atherosclerosis must be excluded. It is therefore hypothesized that atherosclerosis in genetically hyperlipidemic animals selectively influences the receptorial arrangement of endothelium, as in other published examples of selective remodeling of receptors in arteries. Endothelial cell receptors may become a new interesting target for the development of drugs to treat atherosc
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Insediamento, reclutamento ed accrescimento di bivalvi eduli su strutture in sospensione nellâ€TMarea del campo sperimentale.
No full textABSTRACT - From December 2003 to November 2004 a research project on the larval settlement of bivalves was carried out in the “Campo Sperimentale”. Each sample consisted of two sets of artificial collectors, consisting each of ten “chinese caps”, ten “pegs” and four “bags”, were tied to a suitable surface long-line system and suspended at -2 and -10 m depth. So each sample consisted of 48 collectors. From December 2003 to November 2004 ten samples were plunged and recovered after about a month, and four after three months. The peak of settlement was in spring-summer period, mostly in August for families Mytilidae, Pectinidae and Veneridae, although some families, as Anomidae and Hiatellidae, settled mainly during the winter season. In August some species of worthless Mytilidae, as Modiolarca subpicta (Contraine, 1835) and Modiolula phaseolina (Philippi, 1844), were rather abundant (188 ind/m2/day on “caps” at 10 m), whereas Mytilus galloprovincialis (Lamarck, 1819) settled between April and July with lower abundance values, mainly on “pegs” and “bags” at 2 m depth. Pectinidae species, Chlamys varia (Linnaeus, 1758), Proteopecten glabra (Linnaeus, 1758) and Aequipecten opercularis (Linnaeus, 1758), present during the whole study period, were mostly abundant in summer (up to 267 ind m-2 day-1) and showed a higher settlement on “bags” and “chinese caps” at 10 m depth. Veneridae, mostly Paphia spp., were rather low (max 36 ind/m2/day on “caps” at 2 m). M. galloprovincialis and Veneridae clearly preferred the most surface collectors, whereas Pectinidae preferred the deepest ones. Moreover, in order to define a suitable spat harvesting strategy throughout the different year periods, a calendar of the settlement, which may be useful for the shellfish producers, was assessed
Insediamento di larve di bivalvi su collettori artificiali in unâ€TMarea a barriere artificiali nel Nord Adriatico.
No full textAbstract: From December 2003 to November 2004 a research project on larval settlement of bivalves was carried out in the Northern Adriatic Sea, using some series of collectors (“Chinese cap”) suspended at -2 and -10 m depth. The study revealed the period and density of settlement, as well as the bathymetric preferences of certain species of bivalves. These studies contribute to the knowledge of the distribution of bivalve larvae in the sea environment
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Settlement, post-larval growth and gonadal development of Chlamys glabra L. in an off-shore site of the Northern Adriatic Sea (Italy).
No full textA study on the settlement of Pectinidae, mainly of Chlamys glabra, on artificial collectors (“onion-bags”) was carried on in a mussel culture plant, one mile off-shore in the Northern Adriatic Sea, northwards the lagoon of Venice. Samplings were collected every three months, from August 2005 since August 2006. Each sampling consisted of twenty bags suspended at different depths (5m, 7m, 9m, 11m, 13m).
The peak of settlement of Pectinidae was in summer at -13m (average 119 individuals m-2 day-1). Very small unidentified Pectinidae were the most abundant component, mainly close to sea bottom; Chlamys varia, C. glabra and Chlamys proteus settled almost uniformly at any depth. The summer-autumn settlement was mostly represented by C. glabra and C. proteus, that preferred to settle at -11m and -13m (average 51 and 87 ind m-2 day-1, respectively). During winter only little quantities of very small unidentified Pectinidae settled. A. opercularis was collected, even if not very abundant (<15 ind m-2 day-1), in the spring sampling; it preferred collectors toward the bottom, particularly those at -11m (average 14 ind m-2 day-1).
At any seasons, the multivariate statistical analysis confirmed the preference of different identified species of Pectinidae for settling near the sea bottom.
From November to April, in order to assess post-larval growth, bimonthly measures of the length of some specimens of C. glabra, collected in the same site during the previous summer and kept in experimental holders, were carried on. The growth was slow between November and February, showing a mean increase of 2mm between November and December and only 1mm between December and February. In April, the mean size increased up to 2.4cm (maximum 3.6cm).
The gonadal development of C. glabra was followed from October to April in specimens from the same holders. The gonadal maturity was reached after about eight months, at length of 4 cm. The scallops did not show presence of any parasites.
In the experimental site, C. glabra seemed to be suitable for farming; this practice should reduce the fishing effort, that is currently hazarding toward depletion of the natural beds of scallops, linked to impact on the benthic communities in the Northern Adriatic sea
Heparin: pharmacological potentials from atherosclerosis to asthma
No full text1. Heparin belongs to a family of polysaccharide species, whose best known property is, undoubtedly, anticoagulant activity. However, heparin has many other pharmacological effects, particularly on the cardiovascular system. 2. The therapeutic use of chronically inhaled heparin has been suggested as prophylaxis in atherosclerosis. 3. Heparin, physiologically stored in mast cells of the respiratory system, has also been recently studied in the prevention of immunological and non-immunological asthmatic attacks. 4. Experimental findings and new hypotheses of heparin action in asthma and atherosclerosis are discussed
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