87,218 research outputs found
Loffredo V., Torromino G., Esposito F., Carboncino A., Cecere A., Mele A., De Leonibus E. "Sex regulates memory capacity"
No full textMemory Capacity (MC) is the number of information maintained in memory. MC is regulated by fronto-striatal dopamine circuit and hippocampus (HP).
Using a modified version of the object recognition task, the DOT/IOT, we have recently showed that adult naïve male mice could discriminate 3,4,6 but not 9 different objects after a 1 min or 24 hrs delay. Moreover, it has been reported that male mice use the HP, as well as humans, to solve the task (Sannino et al 2012, Olivito et al 2014; Sugita et al 2015).
To report sex differences influencing MC, we have challenged 3 months old mice (males and females) with the 6-DOT (highest memory load), testing them at different time points.
We have found that 3 months old female mice properly perform the 6-DOT when tested at 1 min delay (Short Term Memory, STM), but they are impaired when tested 24 hr later (Long Term Memory, LTM). Female mice properly perform the 6-IOT (lowest memory load) independently on the delay.
We hypothesized that the impairment in LTM could reflect sex regulated differences in the use of different neuronal circuits to solve the task. Therefore, we are performing c-fos immunohistochemical analysis as an index of stimuli-induced neuronal activation on the HP and the prefrontal cortex, at different time points after exposing the animals to the 6-DOT. Preliminary data show that female mice, differently from males, do not activate the HP.
Sex-regulated neuronal activation might be relevant to understand the higher impact of dementia in women as compared to men
I disturbi del comportamento alimentare. L’approccio multidisciplinare per un intervento efficace
No full textAutotraducción, poder y modernidad : El caso de José María Arguedas
No full textThis article aims to reflect on the self-translation of the Peruvian author José María Arguedas, by analysing the poem “Jetman, Haylli / Oda al jet”, written in Quechua and translated into Spanish by the same author and compiled in Katatay / Temblar (1972). Arguedas, considering self-translation as a tool to translate the social and cultural heterogeneity of America, tells the image of a continent that demands a non-hierarchical dialogue with ‘the West’. Self-translation is a form of cultural resistance against the hierarchies of power and representation according to which the indigenous would lose their ‘authenticity’ by coming into contact with modernity
Le tecniche del "crudo" dal manuale all'inventario. Il passaggio al moderno tra marginalità e alternativa"
No full textCangemi editor
Narrating the 1687 Lima Earthquake: Institutions and Devotions in the Face of Catastrophe
No full textSu di un caso di linfoma benigno di Castleman del mediastino.
No full textE' descritto un caso di tumore di Castleman del mediastin
Resezione di 4 coste per displasia fibro-cistica controllo a 8 anni. 1975.
No full textSi descrive la resezione di più coste per displasia fibro-cistic
Libro “Malattie dell’apparato respiratorio e del mediastino”pag. 308, Cuzzolin Editore 2002
No full textSono trattate le malattie dell'apparato respiratorio e del mediastino di interesse medico e chirurgico
Towards a better understanding of the economics of customer satisfaction: An analysis of customer satisfaction, spending levels and spending patterns
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