419 research outputs found

    Customer Car Preference Options : A Case Of Mercedes-Benz

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    Mercedes-Benz customers are in for challenging decisions when selecting the next Mercedes-Brenz vehicle. The Russo-Ukranian war has had a price increase on fuels used in Mercedes-Benz vehicles. The purchasing power has decreased in cause of inlfation for the Mercedes-Benz customer. The aim of this thesis was to map out the Mercedes-Benz customers preferences for the next desired vehicle, because of the current challenging times. Which drivetrain would the most popular in the current situation, diesel, petrol, hybrid or electric variants, what bodystyle is the most popular for the Mercedes-Benz customer, SUV, estate, sedan, hatchback or shooting brake are all the questions that need to be answered. In the theoretical framework the author also goes through the history of the drivetrains to see where it all began with each drivetrain. For the emperical section the data collected can be applied to use in businesses in the automotive sector especially if the data is suitable for the businesses, it can be used in any way they see fitting. The results of the thesis show that the most popular drivetrains were the internal combustion variants, diesel was the most popular and petrol was second, when the customer is seeking to buy a Mercedes-Benz vehicle at the moment. The most popular bodystyles were Estate, Sedan and SUV variants of the Mercedes-Benz lineup

    Ikigai: A reason for Being A Holistic Vision of Mercedes-Benz 2030

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    This Master thesis was developed for Mercedes-Benz AG. The following report elaborates the steps taken in developing a holistic interior vision for ‘Sustainable Luxury’ of Mercedes-Benz. In seek of representation for the future societal needs, and possible future challenges and opportunities in terms of holistic mobility conceptualisation, the research took place in the rural areas of Japan. Therefore, this project is aimed at ‘Self-reliant people accepting innovation raised on the traditional values’. These people are seeking the segregated life, focused on the abundant luxury of time, bonds of smaller communities, and personal fulfilment. Cherishing the community traditions, innovation is acceptable if it preserves the experiential domain of respect towards community members and the environment. To fulfil the demand for such a context, the mission was ‘to achieve a perception of an abundance of less within the experience and perception of the product while keeping the identity of the brand intact.’ As the reconciliation between sustainability and luxury indicates the change of expression of luxury in means of a form, the qualities of the premium experience are set to keeping the utmost feeling of safety and physical ease leading to comfort. Therefore, ‘encountering a moment for yourself, within a shared experience, in comfort.’ was set as the desired interaction. The ideation led to the development of three concept ideas, which were further validated and iterated leading to the conclusive vision ‘Ikigai: A reason for being’. Ikigai presents mobility solution as part of the holistic system of sustainability and manifests as a contribution to the context. The vision ‘Ikigai’ is a Level 4 shared mobility service by Mercedes-Benz, intended for the rural communities of Japan. The on-demand service, utilising the Mercedes-Benz municipal vehicle, grants community residents overcoming the dependence on the pre-scheduled, public transportation of the area. The private zones in the interior space are providing users with a possibility for individual focus and relaxation while in a shared environment. Ikigai’s minimalistic interior is enriched by the works of local craftsman. The material finishings of unique algae-based materials and bio-luminescent lights, produced in the village, are limited to the vehicle design specific to the area. Consequently, the car simultaneously represents exclusivity of the local craftsmen and uniqueness of the tradition, sharing them in rides beyond the borders of the village. The brand remains to provide unique personal experiences within innovative products. Meticulous attention to details and high build quality bring it to the class of its own in providing a sense of safety and physical ease leading to Mercedes-Benz comfort.Design for Interactio

    Diverse biological activities displayed by phenothiazines, benzo[a]phenothiazines and benz[c]acridins (Review)

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    This review summarizes our experiments which are investigating the relationship between the structure and activity of mainly phenothiazines, benzo[a]phenothiazines and benz[c]acridines. Phenothiazines had potent antiplasmid and antibacterial activities, but induced weak antimicrobial activity in vivo. Their antiplasmid activity seemed to be enhanced by Cl- or CF3- substitution at the 2C position of phenothiazines and modified by the side-chain length and hydrophobicity. Benzo[a]phenothiazines did not show any significant antiplasmid or antibacterial activity, but stimulated the differentiation of human myelogenous leukemic cell lines and natural killing activity of human peripheral blood mononuclear cells in vitro, and induced antimicrobial activity in vivo. Circuit current energy (CRE), circuit current (CC), bond current (BC), diatropic and paratropic properties of benzo[a]phenothiazines might be correlated with their biological activity. Benz[a]acridine showed both in vitro and in vivo antimicrobial activities, and carcinogenic activity for skin tumor. The carcinogenic benz[c]acridines showed out-of-phase in the L-region and their energy was accumulated in the K-region of the molecular orbitals. The results suggest the involvement of different molecular orbitals for the expression of various biological activities by phenothiazines, benzo[a]phenothiazines and benz[c]acridines

    What Daimler-Benz has learned as an industrial partner from the Machine Learning Project StatLog

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    Author of this paper was co-ordinator of the Machine Learning project StatLog during 1990-1993. This project was supported financially by the European Community. The main aim of StatLog was to evaluate different learning algorithms using real industrial and commercial applications. As an industrial partner and contributor, Daimler-Benz has introduced different applications to StatLog among them fault diagnosis, letter and digit recognition, credit-scoring and prediction of the number of registered trucks. We have learned a lot of lessons from this project which have effected our application oriented research in the field of Machine Learning (ML) in Daimler-Benz. We have distinguished that, especially, more research is necessary to prepare the ML-algorithms to handle the real industrial and commercial applications. In this paper we describe, shortly, the Daimler-Benz applications in StatLog, we discuss shortcomings of the applied MLalgorithms and finally we outline the fields where we t..

    Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy

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    BACKGROUND: In the heart, cytoplasmic actin networks are thought to have important roles in mechanical support, myofibrillogenesis, and ion channel function. However, subcellular localization of cytoplasmic actin isoforms and proteins involved in the modulation of the cytoplasmic actin networks are elusive. Mena and VASP are important regulators of actin dynamics. Due to the lethal phenotype of mice with combined deficiency in Mena and VASP, however, distinct cardiac roles of the proteins remain speculative. In the present study, we analyzed the physiological functions of Mena and VASP in the heart and also investigated the role of the proteins in the organization of cytoplasmic actin networks. RESULTS: We generated a mouse model, which simultaneously lacks Mena and VASP in the heart. Mena/VASP double-deficiency induced dilated cardiomyopathy and conduction abnormalities. In wild-type mice, Mena and VASP specifically interacted with a distinct αII-Spectrin splice variant (SH3i), which is in cardiomyocytes exclusively localized at Z- and intercalated discs. At Z- and intercalated discs, Mena and β-actin localized to the edges of the sarcomeres, where the thin filaments are anchored. In Mena/VASP double-deficient mice, β-actin networks were disrupted and the integrity of Z- and intercalated discs was markedly impaired. CONCLUSIONS: Together, our data suggest that Mena, VASP, and αII-Spectrin assemble cardiac multi-protein complexes, which regulate cytoplasmic actin networks. Conversely, Mena/VASP deficiency results in disrupted β-actin assembly, Z- and intercalated disc malformation, and induces dilated cardiomyopathy and conduction abnormalities

    Sobre a origem e a tradição do Feindbild Islão

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    Following the publication of Thilo Sarrazin’s book Deutschland schafft sich ab. Wie wir unser Land aufs Spiel setzen (“Germany is Annulling Itself: how we risk our country’s future”), this article presents a reflection on cultural xenophobia and racism in contemporary Europe. The author shows the roots of Feindbild Islam and how it was built up over centuries, invoking a Manichean world and relieving social and political frustrations. Benz demonstrates that today, as in the past, the xenophobic discourse, which is growing in Germany and Europe in general, above all reveals a profound ignorance about Islam.Tomando como ponto de partida a publicação do livro de Thilo Sarrazin Deutschland schafft sich ab. Wie wir unser Land aufs Spiel setzen («A Alemanha está a anular‑se. Como arriscamos o futuro do nosso país»), o presente texto apresenta uma reflexão sobre a xenofobia e o racismo cultural na Europa contemporânea. O autor demonstra as raízes seculares do Feindbild Islão e como este foi construído ao longo dos séculos, invocando um mundo maniqueísta e aliviando frustrações políticas e sociais. Benz demonstra que hoje, tal como no passado, o discurso xenófobo, em crescimento na Alemanha e na Europa em geral, revela acima de tudo um profundo desconhecimento sobre o Islão

    Synthesis and Evaluation of Duocarmycin and CC-1065 Analogues Incorporating the 1,2,9,9a-Tetrahydrocyclopropa[<i>c</i>]benz[<i>e</i>]-3-azaindol-4-one (CBA) Alkylation Subunit

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    An efficient eight-step synthesis (53% overall) and the evaluation of 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]-3-azaindol-4-one (CBA) and its derivatives containing an aza variant of the CC-1065/duocarmycin alkylation subunit are detailed. This unique deep-seated aza modification provided an unprecedented 2-aza-4,4-spirocyclopropacyclohexadienone that was characterized chemically and structurally (X-ray). CBA proved structurally identical with CBI, the carbon analogue, including the stereoelectronic alignment of the key cyclopropane, its bond lengths, and the bond length of the diagnostic C3a−N2 bond, reflecting the extent of vinylogous amide (amidine) conjugation. Despite these structural similarities, CBA and its derivatives were found to be much more reactive toward solvolysis and hydrolysis, much less effective DNA alkylating agents (1000-fold), and biologically much less potent (100- to 1000-fold) than the corresponding CBI derivatives

    Cotxe Mercedes Benz T-80m participant a la I Copa Tibidabo

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    BoTítol atorgat pel catalogador. Cap al 1909 la casa de Mannheim construí unes poque unitats equipades amb un potent motor de 4 cilindres (21.500 cc i 200 CV.) i transmissió per cadena, per competir en a proves curtes i batre rècords mundials de velocitat: el T-80 conegut també co a 'Blitzen Benz', fou el primer cotxe de la història a superar els 200 km/h. El vehícle que aparegué a la Av del Tibidabo era la cuarta unitat construida i malgrat l i la brevetat de del tortuós trajecte poc adient a la seva considerable masa, guanyà la prova. Informació obtinguda d'en Manel Bar
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