1,720,971 research outputs found
Implementazione della diagnostica non invasiva a supporto della pratica clinica
Full text linkThe use of tools, intended broadly as all those objects through which we can interact with the environment and modify it, is part of our daily experience. For example, when we use a smartphone to buy a train ticket we are in fact acting on the environment, causing tangible consequences through a tool. In the human species, the use of tools is the result of a complex cognitive process, which requires mentally representing the possibility of achieving a goal in a mediated, rather than direct, manner. The link between tools and the development of the human species is central. By studying the tools that the different hominids have been able to produce and use, paleoanthropologists have always tried to characterize the evolutionary steps which led to the origin of our species and our cognitive abilities. Over time, these first tools take on more and more elaborate shapes, and the brain, in turn, follows an evolutionary path that leads to a considerable increase in size. In fact, for this particular interaction, we can speak of a process of co-evolution. By examining the history of medicine at the same time, it is clear that the evolution of the latter also goes hand in hand with technological progress and consequently with the instruments supporting it. New technologies have in fact transformed medicine and the imminent advent of artificial intelligence will be the element capable of upsetting and giving it an unprecedented evolutionary drive, effectively providing the link between tangible and abstract tools. In Dermatology, non-invasive diagnostic techniques refer to a group of in-vivo methods that go hand in hand with the clinical evaluation of the patient and that use high-tech equipment for the study and diagnosis of skin diseases, both of an inflammatory and neoplastic nature. This thesis examines some of the most modern and innovative diagnostic equipment in Dermatology, in order to show their potential and benefits in the delicate and fundamental "diagnostic moment" and in the validation of the results obtained from laboratory studies in clinical applications, a typical example of translational research
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
A case of Scalp Rosacea treated with low dose doxycycline and probiotic therapy and literature review on therapeutic options
Full text linkRosacea is a common chronic inflammatory disorder showing a wide range of clinical features such as telangiectasia, erythema, papules, and pustules primarily involving the central part of face (forehead, cheeks and nose) although extra facial manifestation have been described. We describe a case of rosacea with predominant scalp involvement successfully treated with a 8-week-course of doxycycline 40 mg once a day and probiotic therapy twice a day (Bifidobacterium breve BR03, Lactobacillus salivarius LS01 1 × 10(9) UFC/dose)
Actinic Keratosis Pathogenesis Update and New Patents
No full textBackground Actinic keratosis is a common premalignant skin lesion. Because of increasing incidence of actinic keratosis, several efforts have been done to detect earlier this premalignant lesion and to improve knowledge on photocarcinogenic pathways of keratinocytes. As a consequence, new discoveries have been done in this field recently. Objective Starting from our previous review on actinic keratosis, we reviewed the literature abo this premalignant lesion, focusing on pathogenesis and new patents for its early diagnosis, in order to highlight the most recent progresses in diagnosis and therapeutic approach of actinic keratosis. Conclusion Although several efforts have been done in the field of actinic keratosis, new upgrades in diagnosis and therapy are needed to detect superficial actinic keratosis earlier, to improve the disease free survival of patient and to threat better the field cancerization
Some Physicochemical Remarks on Spontaneous Emulsification of Vitreal Tamponades
Full text linkThe importance of gravitational instability in determining the emulsification of vitreal tamponades is discussed. Theoretical results and numerical simulations indicate that the spontaneous formation of water-silicon oil is a rare event and that the very low concentration of surface active agents cannot justify the systematic formation of emulsions. The gravitational instabilities seem to play the main role. Our theoretical results seem in agreement with the experimental evidences; furthermore they indicate a future research line for the improvement of endotamponades. Indeed, the use of biodegradable antifoam may avoid the formation of bubbles and delay the formation of emulsions
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