1,720,978 research outputs found

    Angiostrongilosi canina: monitoraggio clinico e parassitologico in animali asintomatici

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    Canine angiostrongylosis is a cardiopulmonary disease emerging in Europe which can be fatal if left untreated. The aim of the present study is to report the laboratory and imaging findings of 5 asymptomatic cases of canine angiostrongylosis and to report the results of faecal monitoring by Baermann test during therapy. The occasional detection of L1 in the faeces of dogs referred for routinary visit suggests that faecal samples can reveal asymptomatic subjects allowing to establish an appropriate treatment before the onset of potentially lethal lesions. A highly variable response was registered at fecal monitoring during treatment in the dogs probably associated to the host and/or to the parasite. To monitor the response to treatment serial tests are needed; the limits of Baermann test are known and a single negative result does not mean control of infection confirming the importance to develop new tests to reach diagnosis and improve monitoring after treatment

    CLINICAL-PATHOLOGICAL ASPECTS OF EIGHT DOGS INFECTED BY ANGIOSTRONGYLUS VASORUM IN SOUTHERN ITALY

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    Angiostrongylus vasorum has been recently reported in central and southern Italy. Although a wide range of clinical signs have been described in association with A. vasorum respiratory disease and the haemorrhagic diatheses predominate. The aim of the present study is to report the different clinical presentations, laboratory and imaging findings of 8 cases of angiostrongilosis. Diagnosis was made by means of larval morphological identification; faecal samples were analysed by the Baermann test and direct microscopic observation. Different treatment protocols were used, and animals weekly monitored by larval detection in faecal samples. These case reports associate different clinical presentations with the presence of A. vasorum infection in dogs and also suggest that angiostrongylosis should be considered as a possible aetiological cause of several clinical conditions. Although A. vasorum can be fatal a prompt diagnosis and appropriate treatment may lead to a complete clinical resolution, as it was in the cases described herei

    Clinical study on twelve naturally Angiostrongylus vasorum infected dogs under treatment.

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    angiostrongylosis is an emerging potentially fatal disease in Europe. Aim of the study- clinical monitoring of twelve naturally Angiostrongylus vasorum naturally infected dogs under treatment. Materials and methods- twelve dogs referred to the Clinical Unit of the Veterinary Faculty of Bari (Italy) were enrolled in the study. Diagnosis was made by means of larval morphological identification on faecal samples analysed by Baermann test and/or direct microscopic observation. A blood sample was collected for haematology, biochemical analysis, serum protein electrophoresis and coagulation profile. Thoracic radiographs and echocardiography was performed. Specific therapy was administered choosing fenbendazole (Panacur Ò, Intervet, Animal Health) and/or Im/Mox (AdvocateÒ spot-on, Bayer) based on the severity of symptoms. The study monitoring was stopped at normalization of clinico-pathological alterations and/or at the end of treatment. During monitoring clinical examination was performed once a week in symptomatic dogs, while laboratory and radiographic controls were performed according to owner availability. Results-the owner complaint was heterogeneous: dyspnea, polypnea and hemoptysis, gradual distension of the abdomen, epistaxis and acute unilateral hyphema, severe coughing. Five cases were presented for routine control visit and one case for ocular specialistic examination. Thoracic auscultation was normal in seven cases, while in the other animals rales, wheezing, muffling of heart sounds and loud bronchovescicular sounds were registered. Thoracic radiographs showed pathological findings in all dogs except for one. Circular areas of radiopacity were observed in four cases. The complete blood count showed anemia from mild to moderate in five cases, leucocytosis in four cases and eosinophilia in six cases. The biochemical examination showed non-specific and non-uniform alterations. Primary hemostasis disorders characterized by thrombocytopenia were detected in three cases, associated or not to alterations of clotting profile. Serum protein electrophoresis showed a variable increase in β globulin fraction in all animals except for two asymptomatic dogs. In general clinical pictures significantly improved in all symptomatic dogs after 1-2 weeks from treatment starting. The reverse to normal of clinico-pathological findings and radiographic abnormalities were variable. Fenbendazole was given in monotherapy in five cases for 21 days. The Im/Mox was administered in monotherapy in five cases and in combination with fenbendazole in two other cases. Conclusions - The reported cases show different clinical presentations associated with the presence of A. vasorum in dogs suggesting that angiostrongylosis should be considered as a possible etiological cause of several clinical conditions. Moreover the occasional detectionof L1 in the feces of five dogs referred for a routine control visit suggest that fecal samples (direct or Baermann test) can reveal asymptomatic subjects (Koch et al., 2009). The detection of L1 in a dog of 12 years reveals the receptivity to infection also in old dogs, although a greater risk of infection is reported in young subjects (Chapman et al., 2004; Barutzki and Schaper, 2009). Thoracic radiographic findings are described in the course of angiostrongylosis with the possibility of abnormalities also in asymptomatic dogs (Boag et al., 2004) as it was in the cases described herein.. The particular aspect of the circular/serpiginous radiopacity described in four cases have not been previously reported; these lesions could be attributed to fistulas created during larval migration from the pulmonary capillaries into the alveoli or to bronchoectasiae. A. vasorum infection can be fatal, thus an early diagnosis and appropriate treatment is auspicable. Although none of clinico-pathological findings are specific, a combination of these findings should increase the index of suspicion also in asymptomatic dogs

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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