1,354,702 research outputs found
The risk assessment of the Vallicelle district located in Camerino
This paper applies the Performance-Base Earthquake Engineering (PBEE) framework to estimate the risk
of a urban district recently hit by an earthquake, in order to compare model prediction with effective damage
observed after the event.
For this purpose, the reinforced concrete buildings of the Vallicelle district of Camerino, are considered.
This district consists of different typologies of structures (Low, Middle and High rise) built at different
times conforming to different seismic codes. After the “Central Italy 2016” earthquake, a detailed survey
of damage was carried out, as well as studies about the seismic hazard of this area, subjected to seismic
wave amplification.
In the PBEE framework, the seismic response of the structures is described by means of fragility curves
proposed in literature according with the typologies of buildings present in the area and a loss analysis in
terms of expected annual losses is carried out. Finally, a comparison with the observed damage experienced
after the seismic sequence is provided.
This work is a summary of the paper published within COMPDYN 2019 (Canuti et al., 2019)
Hydrogeologic budgeting of a fractured aquifer supported by tunnel drained–groundwater data
The paper deals with the defining and estimating the hydrogeologic components of the runoff relatively to three Appenninic mountainous watersheds in Northern Tuscany (Italy). The closing of the groundwater budget equation and the estimate of the effective infiltration are supported by the data of groundwater drainage from tunnels bored for the High Speed railway connection between Florence and Bologna. The comparison between the surface hydrological regime of springs and creeks, the discharge monitoring of the tunnel and the effects on the environmental flows of the forced drainage, has put in evidence either a higher than expected value of the coefficient of effective infiltration, considered as the ratio between effective infiltration in the watershed and effective rainfall, or the importance of the interflow in the determination of the runoff coming out from the watershed. As a consequence of a geological, structural and tectonic control, the permeability of the local regional aquifer, so far considered a low permeability unit (Marnoso-Arenacea formation, a turbiditic layered marl and sandstone), attains an aquifer type behavior with important consequences either for the technical obstacles to boring the tunnel or for the groundwater resources exploitation and management of the watershed. In the paper a methodology to estimate the dynamic resource from the analysis of the recession curve of creeks and springs and to derive the environmental flow of a creek, both with the availability of few discharge data, is presented. Hydrogeological considerations on local and regional groundwater flow systems are also supported by a hydrochemical analysi
Rhinolophus canuti Thomas & Wroughton 1909
76. Knud’s Horseshoe Bat Rhinolophus canuti French: Rhinolophe de Knud /German: Knud-Andersen-Hufeisennase / Spanish: Herradura de Knud Other common names: Canut's Horseshoe Bat, Canuti Horseshoe Bat Taxonomy. Rhinolophus canuti Thomas & Wroughton, 1909, “ Island ofJava,” Indonesia. Restricted by O. Thomas and R.. Wroughton in 1909 to “Kalipoetjang, Tji-Tandoei River, S.Java.” Rhinolophus canuti is included in the euryotis species group and is probably related to. creaghi and R arcuatus, although it has not yet been included in any phylogenetic studies. Two subspecies recognized. Subspecies and Distribution. . c. canuti Thomas & Wroughton, 1909 — Java (three localities), and Nusa Barong ail'd Bali Is. . c. timorensis R. E. Goodwin, 1979 — Timor I. Descriptive notes. Head-body 51-62 mm, tail 19-24 mm, ear 21-24- 1 mm, forearm 47-6-51- 2 mm. Fur is long and fine. Dorsal pelage is variable, ranging from dark red to wood brown (hairs paler at base), and ventral pelage varies between wood brown and light drab. Ears are large. Noseleafhas concave sided lancet; connecting process is very low (slightly more developed in timorensis', and curved, and has fringe of hairs along the edge; sella gradually narrows to rounded tip and there is a tuft ofhair between sella and lancet (hairs much less dense than in Creagh’s Horseshoe Bat, R creaghi), which varies in color from reddish brown (timorensis) to straw yellow (canuti); horseshoe is wide (c.ll mm). Skull is heavily built (zygomatic breadth slightly exceeding mastoid breadth); anterior median swellings are well inflated and extend posteriorly; lateral swellings are prominent; posterior swellings are relatively reduced; rostral profile is sharply concave; sagittal crest is well developed; frontal depression is well to moderately developed; supraorbital crests have sharp ridges. C 1 is moderately strong and long; P2 is relatively large and within the tooth row, or crowded slighdy out of line; P3 is small and completely extruded, or rarely missing; P9 and P4 are in contact Dental formula is the usual of 32 teeth for the genus, or only 30 teeth when a lower premolar is missing. Habitat. Found almost exclusively in intact forest, although it may occasionally forage over cultivated land. Recorded at 550 m on Timor. Food and Feeding. No information. Breeding. No information. Activity patterns. Knud’s Horseshoe Bat roosts in caves by day. Movements, Home range and Social organization. Knud’s Horseshoe Bat appears to roost in large colonies. Status and Conservation. Classified as Vulnerable on The IUCNed List. Knud’s Horseshoe Bat is currendy only known from a few scattered localities. It prefers undisturbed forests, which severely limits its distribution. The species was thought perhaps to be extinct inJava, but recent sampling efforts have shown that it is still present. This species is threatened by deforestation and roost disturbance throughout its distribution. Bibliography. Csorba eta/. (2003), Goodwin (1979), Hutson, Kingston & Csorba (2008), Ikranagara eta/. (2014).Published as part of Burgin, Connor, 2019, Rhinolophidae, pp. 280-332 in Handbook of the Mammals of the World – Volume 9 Bats, Barcelona :Lynx Edicions on page 317, DOI: 10.5281/zenodo.374852
Biochemical Composition and Antioxidant Properties of Lavandula angustifolia Miller Essential Oil are Shielded by Propolis Against UV Radiations
UV radiations are principal causes of skin cancer and aging. Suntan creams were developed to protect epidermis and derma layers against photodegradation and photooxidation. The addition of antioxidant plant extracts (i.e. essential oil) to sunscreens is habitually performed, to increase their UV protective effects and to contrast pro-radical and cytotoxic compounds present in these solutions. According to these observations, in the present work, the alteration of chemical composition and bioactive properties of Lavandula angustifolia Miller essential oil, exposed to UV light, was investigated. UV induced a significant deterioration of lavender oil biochemical profile. Moreover, the antioxidant activity of this solution, in in vitro tests and directly on B16-F10 melanoma cells, greatly decreased after UV treatment. Our results also showed that essential oil was shielded from UV stress by propolis addition. Even after UV treatment, bee glue highly protected lavender oil secondary metabolites from degradation and also preserved their antiradical properties, both in in vitro antioxidant assays and in cell oxidative damage evaluations. This research proposed propolis as highly efficient UV protective and antiradical additive for sunscreens, cosmetics and alimentary or pharmaceutical products containing plant extracts
Characterisation of the phenolic and flavonoid fractions and antioxidant power of Italian honeys of different botanical origin
BACKGROUND: Twenty-seven Italian honey samples of different floral origin were analysed for total phenolic and flavonoid contents by a spectrophotometric method and for antioxidant power and radical-scavenging activity by the ferricreducing/antioxidant power(FRAP) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) assays respectively. In addition, the phenolic and flavonoid profiles were analysed using high-performance liquid chromatography with UV detection (HPLC-UV). RESULTS: The results of this study showed that honey contains copious amounts of phenolics and flavonoids. HPLC-UV analysis showed a similar qualitative polyphenolic profile for all honey samples analysed. The main difference among samples was in the contribution of individual analytes, which was affected by floral origin. Total phenolic and flavonoid contents varied from 60.50 to 276.04 mg gallic acid equivalent kg(-1) and from 41.88 to 211.68 mg quercetin equivalent kg(-1) respectively. The antioxidant capacity was high and differed widely among samples. The FRAP value varied from 1.265 to 4.396 mmol Fe2+ kg(-1), while the radical-scavenging activity expressed as DPPH-IC50 varied from 7.08 to 64.09 mg mL(-1). Correlations between the parameters analysed were found to be statistically significant (P < 0.05). CONCLUSION: The present study shows that honey contains high levels of phenolics and flavonoids and that the distribution of these compounds is influenced by the honey's floral origin. (C) 2009 Society of Chemical Industr
Collegii ethici disputatio IV. De pietate & iustitia in Regia Academia Aboënsi, praeside ... m. Michaele O. VVexionio pol. ac histor. prof. ordin. celeberrimo ac laudatissimo praeceptore ac mecaenate reverenter suspiciendo. Respondente Petro Johan Reftelio Gotho ser. reg. maj. alumno. Publicae ventilationi commissa ad diem 19 Februarij.
Variantti A.Arkit: 1 arkintunnukseton lehti, A-B4.Invokaatio: D.O.M.A.Dedikaatio: Enevaldus Svenonius, Iohannes M. Ketarmannus, Simon Anglenius, Michael Canuti Wisius
Antiradical activity of phenolic metabolites extracted from grapes of white and red Vitis vinifera L. cultivars
A diet rich in plant foods is strongly recommended for its beneficial effect on human health. In fact, plant secondary metabolites may exert various biological activities on mammalian cells. Among them, phenolics are excellent natural antioxidants able to rescue cell redox unbalance responsible for the onset of different pathologies. For these reasons, the present work was focused on the study of grape extracts obtained from eight different Italian Vitis vinifera cultivars, quite rare in Italian viticulture and not yet completely chemically characterized. For each preparation, total simple phenolic, flavonoidic and anthocyaninic content was measured through spectrophotometrical assays, while detailed biochemical profile was revealed by LC-MS analyses. In order to valorize the products of these varieties and increase our knowledge about their potential healthy role, the antioxidant power of the samples was evaluated by two different in vitro antiradical tests: DPPH and FRAP. Moreover, free radical scavenging properties of eleven grape pure compounds were investigated, with the aim to: a) compare their real antiradical property with the theoretical one; b) identify which one of them possessed the best bioactivity; c) understand how they might singularly contribute to the nutraceutical effect of the whole grapevine phytocomplex
Discursus politicus de prudentia tum legislatoriâ tum politicâ seu civili, Deo ter opt. maximo benignè annuente, in novâ Academiâ Aboënsi exhibitus praeside m. Michaele O. VVexionio polit. & hist. professore pub-ordinario respondente Enevaldo S. Pontano Smol. s. r. m.tis stipend. Ad quem ventilandum reverendi consultissimi & clarissimi domini professores & adsessores, praeter ordinarios opponentes, amicè & officiosè invitati fuerunt in auditorio majori 18. Decembris 1641.
Arkit: A-B4 C2.Dedikaatio: Nicolaus Krokius, Nicolaus Rubenius, Zacharias Rothovius, Benedictus P. Komstadius, Johannes M., Christiernus A. Osaengius, Bononius Hieronimi, Olaus Nic. Marelander, Johannes Canuti, Petrus Osaengius, Benedictus, Gudmundus Cauuti [!], Petrus Pauli.Esipuhe.Gratulaatio: Petrus S. Lidenius, Gudmundus J. Rothovius, Dietericus P. Moll.Suomennettu nimellä: Valtio-opillinen väitöskirja järkevyydestä
Hydroalcoholic extract of Spartium junceum L. flowers inhibits growth and melanogenesis in B16-F10 cells by inducing senescence
Background: Ultraviolet light exposure generates, in human tissues, radical species, which represent the main cause of photo-aging, DNA damage and skin cancer onset. On the other hand, Mediterranean plants, being continuously subjected to high solar radiation levels, are naturally adapted to take on this type of abiotic stress, thanks to the production of antioxidant secondary metabolites. For these reasons, several plant extracts were documented to be excellent antineoplastic drugs. Purpose: We investigated the potential antitumor activity of the flower extract obtained by Spartium junceum L., a Mediterranean shrub, correlating it with the plant metabolic profile. Study design: After selecting the best extraction method to obtain as more secondary metabolites as possible from S. junceum flowers, we characterized the extract metabolic content. Then, by in vitro analyses, the antioxidant profile and the antineoplastic activity on B16-F10 murine melanoma cell of our extract were investigated. Methods: Spectrophotometric assays, HPLC-DAD and GC-MS analyses provided us information about flower extract composition and antioxidant activity. MTT assay and Trypan Blue exclusion test were performed to assess the extract toxicity and the viability, after treatments, of B16-F10 cancer cells and of C2C12 murine myoblasts. In vitro experiments (i.e. cytofluorimetry, protein analysis and qPCR) allowed us to analyze the effect of the plant extract on B16-F10 cell redox state, melanogenesis and cell cycle. Senescence induction was investigated by using a specific kit. Results: We observed that the hydroalcoholic extract of S. junceum flowers (HFE) strongly inhibited B16-F10 murine melanoma cell proliferation, while just a feeble effect was observed on C2C12 murine myoblasts. Moreover, we found that HFE exerted a pro-oxidant activity on melanoma cells, inhibited melanogenesis and caused cell cycle arrest in G2/M phase, inducing senescence. These anti-cancer properties of HFE could be related to the rich metabolic profile of the extract that we characterized by HPLC-DAD and GC-MS analyses. Conclusion: This evidence suggests that S. junceum phytocomplex can be used as a selective, nontoxic, economic and easily available anticancer drug
APPLICATION OF THE EMPIRICAL PREDICTIVE DAMAGE MODEL OF HISTORICAL CHURCHES
Strong seismic events are the main cause of serious damage to cultural heritage, especially to historical churches characterized by a lack of efficient resisting mechanisms and by high vulnerability due to their structural systems peculiarities. Their poor seismic performance is demonstrated by the recurrence of specific seismic damage mechanisms. In this paper, an empirical probabilistic damage predictive model recently presented in the literature is used to provide a scenario dependent risk assessment in a seismic prone area in Italy. In this response model, the damage is expressed by a continuous index and the seismic action is described by a scalar intensity measure. For the illustrative case study, a sample of churches falling into a limited area of Marche Region, hit by the Central Italy 2016 seismic sequence, has been chosen.
The sample includes all the historical churches belonging to the Archdiocese of Camerino-San Severino. The damage scenario following a seismic event of magnitude 5.8, generated by the Camerino fault, has been evaluated to illustrate the capability of this model in the prediction
of post-earthquake situation. Risk maps obtained by means of the method presented in the paper, can provide a notable support to the organization of post-event emergency actions and to the planning of preventive actions for the risk mitigation
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