1,720,974 research outputs found
Siringomielia cervicale secondaria a singole masse intracraniche occupanti spazio nel cane: caratteristiche di risonanza magnetica e fattori di rischio
Full text linkThe aims of the present study are 1), to investigate cervical syringomyelia (SM) secondary to single space-occupying intracranial lesions in dogs, and 2), to evaluate potential risk factors based on brain and cervical magnetic resonance imaging (MRI) studies conducted for the diagnosis of these two conditions. As a multicentric retrospective single cohort study, we recruited a population of dogs affected by a single space-occupying brain lesion and we divided it into two groups, based on the presence or absence of cervical SM. These two groups were compared for signalment (age, sex, and cranial morphology) and for MRI findings (relative intracranial mass volume, relative perilesional oedema volume, mass effect, ventriculomegaly and cerebellar herniation). Based on the current knowledge about SM and its aetiopathogenesis, our initial hypothesis considered factors predisposing to cervical SM development being lesions with substantial relative mass volume, localisation in the caudal cranial fossa, cerebellar transforaminal herniation and/or obstructive hydrocephalus.
Our statistical analysis revealed that intracranial mass with relative volumetric index higher than 0.028 and causing cerebellar transforaminal herniation and/or obstructive hydrocephalus predispose to cervical SM formation. Therefore, in presence of these findings on a brain MRI study is indicated to extend the diagnostic imaging protocol to the cervical spine to check for the potential presence of SM. Conversely, the detection of cervical SM, in the absence of any additional cervical disease, addresses the clinician to extend the MRI study to the brain for the search of a potential primary mass lesion
Risk factors for diskospondylitis in dogs after spinal decompression surgery for intervertebral disk herniation
No full textOBJECTIVE
To determine the incidence of and risk factors for development of postop- erative diskospondylitis (POD) in dogs that underwent spinal decompression surgery for intervertebral disk herniation (IVDH).
DESIGN
Retrospective single cohort study.
ANIMALS
372 dogs that underwent spinal decompression surgery for IVDH between January 2007 and January 2011.
PROCEDURES
Medical records of dogs were retrospectively reviewed. Data regarding signal- ment, type and anatomic site of IVDH, severity of neurologic signs, type of surgery, duration of anesthesia, esophageal temperature during surgery, and use of corticosteroid drugs were analyzed for associations with POD.
RESULTS
POD developed in 8 of 372 (2.2%) dogs. Univariate analysis revealed that German Shepherd Dogs had 9.8 times the odds of POD, compared with the odds for other breeds. In addition, dogs > 8.8 years of age, weighing > 20 kg (44 lb), or having disk protrusions were at higher risk of developing POD than were other dogs.The only factor that retained a signi cant association with POD after controlling for other factors in multivariate analysis was body weight > 20 kg.
CONCLUSIONS AND CLINICAL RELEVANCE
Factors identi ed in this study may be useful for prediction of POD, an appar- ently uncommon outcome, in dogs undergoing spinal decompression surgery for IVDH. Dogs at higher risk than others, particularly those weighing > 20 kg, should be monitored carefully in the immediate postoperative period, and signs of worsening neurologic condition after initial improvement should be promptly investigated
Primary Diffuse Leptomeningeal Gliomatosis in two dogs
No full textClinical, neuroimaging, and neuropathological findings of 2 cases of canine primary diffuse leptomeningeal gliomatosis are described. Magnetic resonance imaging and histopathological examination of the brain revealed diffuse leptomeningeal alterations with no parenchymal involvement. These cases share many similarities with the same disease in humans
Un caso di Tumore a Cellule Granulari del midollo spinale del gatto: reperti clinici, di diagnostica per immagini e istopatologici
No full text
Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation
Full text linkBackground: Ascending/descending myelomalacia (ADMM) is a severe complication of thoracolumbar intervertebral disk herniation (TL-IVDH) in dogs.
Hypothesis/Objectives: To investigate the prevalence and risk factors for ADMM in nonambulatory dogs with surgically treated TL-IVDH.
Animals: Six-hundred and fifty-two client-owned dogs evaluated for TL-IVDH that underwent decompressive spinal surgery.
Methods: Retrospective medical record review from February 2007 through December 2015.
Results: Thirteen dogs developed ADMM, with an overall prevalence of 2.0%. The prevalence of ADMM was 0% in dogs with neurological signs graded 1 or 2 at admission or before magnetic resonance imaging (MRI) or surgical procedures, 0.6% in dogs with neurological signs graded 3, 2.7% in dogs with neurological signs graded 4, and 14.5% in dogs with neu- rological signs graded 5. Age (4.57 were significant risk factors in the univariate analysis for development of ADMM.
Conclusions and Clinical Importance: The factors identified in this study may be useful for the prediction of ADMM. Multicenter studies with a higher number of dogs with ADMM are required to confirm these data
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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