1,721,039 research outputs found
Treatment with vacuum-assisted closure and cryo-preserved homologous de-epidermalised dermis of complex traumas to the lower limbs with loss of substance, and bones and tendons exposure
No full textJ Plast Reconstr Aesthet Surg. 2008 Dec;61(12):1507-11. Epub 2007 Nov 13.
Treatment with vacuum-assisted closure and cryo-preserved homologous de-epidermalised dermis of complex traumas to the lower limbs with loss of substance, and bones and tendons exposure.
Brandi C, Grimaldi L, Nisi G, Silvestri A, Brafa A, Calabrò M, D'Aniello C.
Source
Department of General and Specialist Surgery, Plastic Surgery Unit, University of Siena, Polyclinic S Maria alle Scotte, Viale Bracci, Sienna, Italy. [email protected]
Abstract
SUMMARY: Lower-limb injuries with loss of tissue and exposure of bones and tendons are an increasing problem. The condition of the wound locally and the patient in general does not always allow immediate and adequate coverage of the structures exposed by the trauma. Therefore, new therapeutic solutions are needed. A reduction in the time that bones and tendons are exposed is essential to achieve complete healing of bone fractures, with reduced risks of infection and less disabling outcomes. The effectiveness of vacuum-assisted closure (VAC) therapy in supporting wound healing and of cryopreserved homologous de-epidermalised dermis (DED) in providing an effective template for re-epithelialisation has been previously reported. We carried out a study to evaluate the effectiveness of the synergistic and combined use of the two methodologies. Eighteen patients with traumatic loss of tissue in the lower limbs, involving exposure of bone and tendon structures, were enrolled in the study. All participants had local, general contraindications to first-instance reconstructions, or both. All patients received a combination of VAC therapy and DED implants. Granulation tissue was obtained in all wounds, with complete coverage of exposed structures. No infections were detected in the cohort, and all patients were prepared for further necessary reconstructive treatments. In our experience, the combination of VAC therapy and DED could, in selected cases, constitute an effective treatment for complex lower limb traumatic injuries with bone and tendon exposure
Il verde pubblico nel nuovo contesto urbano postpandemico
No full textL’esperienza della pandemia da Covid-19 obbliga, tra l’altro, le città a modificare il proprio tradizionale approccio
ai regimi emergenziali. I fenomeni di crisi – non più solo economica, ma anche sanitaria e ambientale –
rappresentano ormai una realtà a cui quotidianamente rapportarsi, realtà che pone richieste inedite, alle quali
occorre fornire risposte adeguate. In tale contesto, il distanziamento fisico, che implica la distanza spaziale,
impone, innanzitutto, una revisione delle modalità di vivere a livello collettivo, ed è questa la ragione per la quale
una delle forme in cui dovrà manifestarsi la resilienza urbana sarà la capacità di riorganizzare l’uso dello spazio
pubblico, per garantire contemporaneamente fruizione collettiva e salvaguardia delle necessarie misure di
distanziamento. Ciò premesso, il paper si propone di indagare le criticità che oggi connotano la gestione del luogo
per eccellenza in cui questa sfida diventa vitale, ovvero lo spazio verde pubblico (verde pubblico attrezzato, verde
urbano, extraurbano e verde di quartiere). In particolare, lo studio – nel mettere in discussione la perdurante
attualità del modello puramente quantitativo di cui al D.M. n. 1444/1968 –si interroga sulle possibili modalità di
conciliazione delle (divergenti) esigenze della fruizione collettiva delle aree verdi, da un lato, e della soddisfazione
degli obiettivi di distanziamento sociale, dall’altro; nonché, più in generale, sulla possibile individuazione di un
modello regolatorio sostenibile ed efficace in grado di valorizzare la centralità del ruolo che le aree verdi sono
destinate a ricoprire nella città resiliente contemporanea
Pentapeptide sharing between Corynebacterium diphtheria toxin and the human neural protein network
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
John Ruskin e le ragioni dell'arte. Alle origini della critica della democrazia liberali
No full textDeliberazione e democrazia
No full textIl saggio intende ripercorrere sinteticamente l'evoluzione del rapporto tra deliberazione e democrazia, affrontando in particolare tre aspetti: la deliberazione nella democrazia diretta e nella prima fase del governo rappresentativo; i principali argomenti dei teorici della democrazia deliberativa; la valutazione della sua praticabilità
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
- …
