58 research outputs found
EMCD real space maps of Magnetospirillum magnetotacticum
No full textStöger-Pollach M, Treiber CD, Resch GP, Keays DA, Ennen I. EMCD real space maps of Magnetospirillum magnetotacticum. Micron. 2011;42(5):456-460
Filtering techniques in the dynamic deformation estimation using multiple strains measured by FBGs
No full textThe first author would like to thank the members of Smart Systems and Structures laboratory at KAIST for
their technical and financial support of the presented research project. The authors also wish to thank Prof.
Chun-Gon Kim and his fiber optic sensor group at the Department of Aerospace Engineering of KAIST for their
help for preparation of the optical sensors and sensing systems
Mechanism of the Aromatic Hydroxylation of Thiophene by Acid-Catalyzed Peracid Oxidation.
No full textA correction appeared : Alexander Treiber,* Patrick M. Dansette, and Daniel Mansuy. Mechanism of the Aromatic Hydroxylation of Thiophene by Acid-Catalyzed Peracid Oxidation. Pages 7261-7266. This article was submitted, reviewed, and published without the Editor's knowledge that two coauthors, Patrick M. Dansette and Daniel Mansuy, were omitted from the author list and that the research was performed at the Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, Universite ´ Rene´ Descartes, CNRS URA400, Paris (now CNRS UMR 8601). The correct listing is as indicated: Mechanism of the Aromatic Hydroxylation of Thiophene by Acid-Catalyzed Peracid Oxidation Alexander Treiber,* Patrick M. Dansette, and Daniel Mansuy Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, Universite´ Rene´ Descartes, CNRS UMR 8601, 45 rue des Saints Pere`s, 75270 Paris Cedex 06, France JO0279725 10.1021/jo0279725 Published on Web 01/24/2003The oxidation of thiophene (1) with peracids in a strongly acidic environment yielded thiophen-2-one (4) as the product of an apparent direct hydroxylation of the thiophene aromatic ring together with the anticipated thiophene-S-oxide dimers, 2a,b, as the main products. Formation of the latter dimers can be rationalized in a straightforward manner by initial oxidation at the sulfur atom of thiophene (1) to yield thiophene-S-oxide followed by subsequent dimerization in a Diels-Alder type reaction. Trapping experiments in the presence of a competing dienophile indicated that thiophen-2-one (4) did not originate from the monomeric thiophene-S-oxide but was the product of an independent reaction pathway. The extent of thiophen-2-one (4) formation correlated with the acidity of the reaction medium and was suppressed in the presence of water, the latter presumably acting as a competing base. As evidenced by the use of 2,5-dideuterated thiophene (1-D), its mechanism of formation involved a 1,2-hydride shift, a feature commonly described in the peracid-mediated epoxidation of aromatic hydrocarbons and indicative for the occurrence of cationic intermediates. In agreement with all these observations we propose a mechanism involving initial protonation of thiophene followed by nucleophilic attack of the peracid in position 2 of the thiophene ring. Intramolecular epoxidation may lead to the formation of thiophene 2,3-epoxide as a highly reactive intermediate that then undergoes heterolytic ring opening and a 1,2-hydride shift to yield thiophen-2-one (4) after a final, acid-catalyzed, isomerization of the double bon
Treiber für nachhaltiges unternehmerisches Handeln: Bedeutung von Spiritualität für Unternehmensgründer
No full textKonzeptionelle Studien der letzten Jahre deuten darauf hin, dass für eine Verwurzelung von Nachhaltigkeit in modernen Unternehmen eine Veränderung der Denkweise der Unternehmensentscheidungsträger notwendig ist. Dabei werden Verantwortung und nachhaltiges Handeln nicht ausschließlich als Instrumente zur Erreichung ökonomischer Ziele eingesetzt, sondern bilden, verankert in der persönlichen Spiritualität, fundamentale Prinzipien und eigenständige Werte. Ziel der vorliegenden Arbeit ist es deshalb, die Zusammenhänge zwischen Spiritualität und unternehmerischer Nachhaltigkeit zu beleuchten. Mit Hilfe von sechs halbstrukturierten Interviews mit GründerInnen und Un-ternehmensführerInnen kleiner und mittlerer Unternehmen des Dienstleistungssektors untersuchte die Autorin, inwiefern die Spiritualität der UnternehmerInnen einen Einfluss auf nachhaltige Entscheidungen in ihren Unternehmen hat. Sie konnte herausfinden, dass Werte und Ansichten, die die individuelle Spiritualität der UnternehmerInnen ausdrücken, als Motivation für nachhaltiges unternehmerisches Handeln dienen können. Überdies identifizierte sie einzelne Werte und Ansichten, die als Treiber für einzelne Dimensionen der Nachhaltigkeit fungieren. Weiterhin entwickelte sie ein Modell, das sowohl persönliche Werte und Ansichten als Teil der Spiritualität, als auch die in der Literatur diskutierten Konzepte Spiritualität am Arbeitsplatz und spirituelle Führung integriert. Dieses Modell kann als Grundlage für weitere Forschung im Kontext von Spiritualität und unternehmerische Nachhaltigkeit dienen. Die Ergebnisse implizieren, dass in Bildung und Gesellschaft verankerte Aktivitäten zur Unterstützung von Spiritualität eine nachhaltige Entwicklung innerhalb und außerhalb von Unternehmen vorantreiben können.Recent conceptual research suggests that in order to embed the concept of sustainability in corporate decision making, a change in the mindset of business leaders is necessary. Instead of exploiting sustainability merely for economic reasons, sustainability should represent fundamental principles and values which are deeply rooted in the manager’s personal spirituality. The goal of this study was to investigate the links between spiritu-ality and corporate sustainability. For this purpose the author conducted 6 semi-structured interviews with founders and owner-managers of small and medium-sized service-providers. She examined to what extent business owner’s individual spirituality has an impact on their decisions on sustainability in the business context. The author found that spiritual values and attitudes can be a motivation for corporate sustainability. Furthermore, she identified particular values and attitudes that drive particular dimen-sions of corporate sustainability. Additionally the author developed a model that in-cludes not only personal values as a part of spirituality, but also workplace spirituality and spiritual leadership, which are discussed in the literature. This model is the ground-work for further research on the topic of spirituality and corporate sustainability. The findings imply that education and society can foster sustainable development by in-graining activities to encourage spirituality
Author response: Resolving the prevalence of somatic transposition in Drosophila
No full textSomatic transposition in mammals and insects could increase cellular diversity and neural mobilization has been implicated in age-dependent decline. To understand the impact of transposition in somatic cells it is essential to reliably measure the frequency and map locations of new insertions. Here we identified thousands of putative somatic transposon insertions in neurons from individual Drosophila melanogaster using whole-genome sequencing. However, the number of de novo insertions did not correlate with transposon expression or fly age. Analysing our data with exons as "immobile genetic elements" revealed a similar frequency of unexpected exon translocations. A new sequencing strategy that recovers transposon : chromosome junction information revealed most putative de novo transposon and exon insertions likely result from unavoidable chimeric artefacts. Reanalysis of other published data suggests similar artefacts are often mistaken for genuine somatic transposition. We conclude that somatic transposition is less prevalent in Drosophila than previously envisaged
Author Correction: Regulation of microRNA biogenesis and its crosstalk with other cellular pathways
No full textAuthor Correction: Insights from serial cardiovascular magnetic resonance imaging show early progress in diastolic dysfunction relates to impaired right ventricular deformation
No full textRace, Gender, and Status: A Content Analysis of Print Advertisements in Four Popular Magazines (includes author interview)
No full textTeaching Life Skills for Middle Schoolers with Autism: A Two-Week Curriculum for 6th-8th Grade Special Educators
No full textThere are children with disabilities that will most likely be faced with difficult and sometimes dangerous situations in the community. While we can never prepare them to avoid all the difficult situations, parents and educators can take proactive steps to support their actions and reactions. Children with an autism spectrum disorder (ASD) need to be safe in the community. Middle schoolers with ASD are especially vulnerable in the community. Middle schoolers are learning functional skills to gain more independence as they grow older. This is true in the classroom as well as the community. There is a need for community skills overall within the moderate/severely disabled population. Their ability to function in a community requires training in the educational setting as well as the community setting. Life skills training has long been considered as an important curriculum for students with disabilities. However, limited research exists of the functional skills training for middle school students with autism. The purpose of this project will be to assess the functional skills knowledge that middle schoolers have and explore further skills needed to navigate safely through the communities they live in. This information will assist the author in creating a two-week curriculum designed to encourage independence in the community for students with ASD. Parent partnerships for education are formed as teachers and families work together to teach functional skills and encourage independence and safety in the community
Behavioral-Based Pedestrian Modeling Approach: Formulation, Sensitivity Analysis, and Calibration
No full textPedestrians are among the travelers most vulnerable to collisions that are associated with high fatality and injury rates. The increasing rate of urbanization and mixed land-use construction make walking (along with other non-motorized travel) a predominant transportation mode with a wide variety of behaviors expected. Because of the inherent safety concerns seen in pedestrian transportation infrastructures, especially those with conflicting multimodal movements expected (crosswalks, transit platforms, etc.), it is important that pedestrian behavior is modeled as a risk-taking stochastic behavior that may lead to errors and thus collision formation. In previous work, the complexity and cost associated with building pedestrian models in a cognitive-based environment weighted down the construction of simulation tools that can capture pedestrian-involved collisions, including those seen in shared space environments. In this paper, a tool that will help evaluate the safety of pedestrian traffic is initiated: an extended modeling framework of pedestrian walking behavior is adopted while incorporating different physiological, physical, and decision-making elements. The focus is on operational decisions (i.e., path choices defined by longitudinal and lateral trajectories) with a pre-specified set of origins and destinations. The model relies on the prospect theory paradigm where pedestrians evaluate their acceleration and directional alternatives while considering the possibility of colliding with other ‘‘particles.’’ Using a genetic algorithm method, the new model is calibrated using detailed trajectory data. This model can be extended to model the interactions between a variety of different modes that are present in different mixed land-use environments.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Transport and Plannin
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