51,033 research outputs found
TropForC-db
No full textTropForC-db (zipped file), containing a series of cross-referenced data tables (.csv) describing (1) sites, (2) plots and their history, (3) measurements of C cycle variables, (4) variables, (5) disturbance/history event type, (6) plant functional types (PFTs)/ species, (7) methodology, and (8) allometries. Also included is a database bibliography and sample R code for joining the tables
A 0.96-mW dB-Linear Variable Gain Amplifier With 0.4-dB Linearity Error Over a 62.4-dB Gain Tuning Range
No full textThis letter presents a low-power dB-linear variable gain amplifier (VGA) with a small linear-in-dB error over a wide gain tuning range. An exponential current ratio is realized in the linear-in-dB control circuit based on the subthreshold I-V characteristic. The VGA is built with subthreshold common-gate transistors as current steering, accurately replicating the exponential current ratio and forming a tunable gain. Implemented in 55-nm CMOS technology, the proposed VGA occupies a compact active area of 0.011 mm2 excluding the buffer. It achieves a linear-in-dB error of 0.4 dB over a gain tuning range of 62.4 dB, corresponding to the state-of-the-art relative error of 0.6%. The proposed design shows constant 80-MHz bandwidth with a power consumption of 0.96 mW. Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic Instrumentatio
DB 2020: Analyzing and Forecasting DB Market Trends
No full textabstract: Over the last two decades, Alternative Project Delivery Methods (APDM), such as Design-Build (DB), have become more popular in the construction industry, specifically in the U.S., and the competition for APDM projects has risen among construction companies. The Engineering News Record (ENR) magazine analyzes DB firms and publishes the list of the top 100 every year. According to ENR articles and many scientific papers, the implementation of DB method has grown drastically over the last decade, however, information about growth trends depending on firm size and segment is lacking. Also missing is knowledge the future market trends over the next five years. Furthermore, public agencies and DB firms may be worried that DB projects do not distribute wealth equally among DB firms. Using the top 100 firms deemed representative of the DB market, the author has divided the market into volumes based on rankings to analyze the total DB market revenue growth. A comparison between international and domestic revenues indicated that the top five DB firms have 64% more involvement in the international market compared to the domestic market. Furthermore, while the research shows increasing market share only for the top five firms, the author has found that (1) a large portion of their market share is due to a large growth in their international market, and (2) revenues for all volumes of the DB market have increased. Moreover, regression and time series analyses allow for the forecasting of the DB market growth, which the author anticipate to move from about 150B in 2020.Dissertation/ThesisMasters Thesis Construction 201
A -109.1 dB/-98 dB THD/THD+N Chopper Class-D Amplifier with >83.7 dB PSRR Over the Entire Audio Band
No full textThis paper reports a chopper Class-D audio amplifier that obtains high PSRR over the entire audio band. A chopping scheme is proposed to minimize intermodulation distortion between pulse-width modulation (PWM) and chopping in the audio band. A high-voltage chopper is developed to handle a 14.4 V PWM signal. Timing matching techniques are proposed to minimize chopping nonidealities which ensure good PSRR and THD. Fabricated in a 180nm BCD process, the prototype obtains a PSRR >109 dB at 217 Hz and >83.7 dB over the entire audio band. It also achieves -109.1 dB/-98 dB THD/THD+N and can deliver a maximum of 13 W to an 8-Ω load.Accepted author manuscriptElectronic Instrumentatio
A - 121.5-dB THD Class-D Audio Amplifier With 49-dB LC Filter Nonlinearity Suppression
No full textClass-D audio amplifiers produce electromagnetic interference (EMI), which often needs to be suppressed by an external LC filter. However, due to component nonlinearity, this filter can itself cause significant distortion. This article presents a class-D amplifier that suppresses LC filter nonlinearity by 49 dB and is robust to ±30% variations in its cutoff frequency. This is achieved by a dual-loop architecture, in which an inner loop provides stability, while an outer loop provides the high gain needed to suppress the LC filter and output-stage nonlinearity. A prototype, implemented in a 180-nm BCD process, achieves -121.5-dB total harmonic distortion (THD) and -107.1-dB THD+N, which is maintained to within 3 dB even as the LC filter cutoff frequency is varied from 62 to 106 kHz. It can deliver a maximum of 21 W into a 4-Ω load with 87% efficiency and 12 W into an 8-Ω load with 91% efficiency, measured at 10% THD. Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic InstrumentationMicroelectronic
Roles of cMyBP-C phosphorylation on cardiac contractile dysfunction in db/db mice
No full textType 2 diabetes mellitus (T2DM) is a metabolic disease and comorbidity associated with several conditions, including cardiac dysfunction leading to heart failure with preserved ejection fraction (HFpEF), in turn resulting in T2DM-induced cardiomyopathy (T2DM-CM). However, the molecular mechanisms underlying the development of T2DM-CM are poorly understood. It is hypothesized that molecular alterations in myopathic genes induced by diabetes promote the development of HFpEF, whereas cardiac myosin inhibitors can rescue the resultant T2DM-mediated cardiomyopathy. To test this hypothesis, a Leptin receptor-deficient db/db homozygous (Lepr db/db) mouse model was used to define the pathogenesis of T2DM-CM. Echocardiographic studies at 4 and 6 months revealed that Lepr db/db hearts started developing cardiac dysfunction by four months, and left ventricular hypertrophy with diastolic dysfunction was evident at 6 months. RNA-seq data analysis, followed by functional enrichment, revealed the differential regulation of genes related to cardiac dysfunction in Lepr db/db heart tissues. Strikingly, the level of cardiac myosin binding protein-C phosphorylation was significantly increased in Lepr db/db mouse hearts. Finally, using isolated skinned papillary muscles and freshly isolated cardiomyocytes, CAMZYOS® (mavacamten, MYK-461), a prescription heart medicine used for symptomatic obstructive hypertrophic cardiomyopathy treatment, was tested for its ability to rescue T2DM-CM. Compared with controls, MYK-461 significantly reduced force generation in papillary muscle fibers and cardiomyocyte contractility in the db/db group. This line of evidence shows that 1) T2DM-CM is associated with hyperphosphorylation of cardiac myosin binding protein-C and 2) MYK-461 significantly lessened disease progression in vitro, suggesting its promise as a treatment for HFpEF
Diabetic (db/db) mice promoted CUP-1 xenograft growth.
No full textCUP-1 cells were injected subcutaneously into the scruff of diabetic db/db mice and non-diabetic control littermates (m+/db) of 10 weeks age. Tumor size was monitored every other day for 2 weeks and tumor volume was calculated as in nude mice. (A) CUP-1 tumor growth in db/db and m+/db mice. Each point represents mean ± S.E.M (n = 10). (B) Representative photographs show db/db (right) and m+/db mice (left) with respective representative excised tumors on day 27 after CUP-1 inoculation. Arrows indicate the site with CUP-1 inoculation. (C) Representative photomicrographs of H&E-stained CUP-1 tumor tissues from db/db (left) and m+/db mice (right) excised on day 27 after CUP-1 inoculation, X400. Atypical cells with large irregular nuclei (stars) and mitotic figures (arrows) were present in CUP-1 tumor tissues. (D) Western blotting confirmed E7 expression in CUP-1 excised xenograft from both db/db and m+/db mice.</p
A Dynamic Zoom ADC with 109-dB DR for Audio Applications
No full textThis paper presents the first dynamic zoom ADC. Intended for audio applications, it achieves 109-dB DR, 106-dB signal-to-noise ratio, and 103-dB SNDR in a 20-kHz bandwidth, while dissipating only 1.12 mW. This translates into the state-of-the-art energy efficiency as expressed by a Schreier FoM of 181.5 dB. It also achieves the state-of-the-art area efficiency, occupying only 0.16 mm2 in the 0.16- μm CMOS. These advances are enabled by the use of concurrent fine and coarse conversions, dynamic error-correction techniques, and a dynamically biased inverter-based operational transconductance amplifier.Accepted author manuscriptElectronic Instrumentation(OLD)Applied Quantum ArchitecturesMicroelectronic
The Rice Annotation Project Database (RAP-DB): 2008 update
No full textThe Rice Annotation Project Database (RAP-DB) was created to provide the genome sequence assembly of the International Rice Genome Sequencing Project (IRGSP), manually curated annotation of the sequence, and other genomics information that could be useful for comprehensive understanding of the rice biology. Since the last publication of the RAP-DB, the IRGSP genome has been revised and reassembled. In addition, a large number of rice-expressed sequence tags have been released, and functional genomics resources have been produced worldwide. Thus, we have thoroughly updated our genome annotation by manual curation of all the functional descriptions of rice genes. The latest version of the RAP-DB contains a variety of annotation data as follows: clone positions, structures and functions of 31 439 genes validated by cDNAs, RNA genes detected by massively parallel signature sequencing (MPSS) technology and sequence similarity, flanking sequences of mutant lines, transposable elements, etc. Other annotation data such as Gnomon can be displayed along with those of RAP for comparison. We have also developed a new keyword search system to allow the user to access useful information. The RAP-DB is available at: http://rapdb.dna.affrc.go.jp/ and http://rapdb.lab.nig.ac.jp/
A 280 <i>μ</i>W Dynamic Zoom ADC With 120 dB DR 118 dB SNDR in 1 kHz BW
No full textThis paper presents a dynamic zoom analog-to-digital converter for use in low-bandwidth (&lt;1 kHz) instrumentation applications. It employs a high-speed asynchronous successive approximation register (SAR) ADC that dynamically updates the references of a fully differential &#x0394; &#x03A3; ADC. Compared to previous zoom ADCs, faster reference updates relax the loop filter requirements, thus allowing the adoption of energy-efficient amplifiers. Fabricated in a 0.16-&#x03BC;m CMOS process, the prototype occupies 0.26 mm&#x00B2; and achieves 119.1-dB peak signal-to-noise ratio (SNR), 118.1-dB peak signal-to-noise-and-distortion-ratio (SNDR), and 120.3-dB dynamic range (DR) in a 1-kHz bandwidth while consuming 280 &#x03BC;W. This results in a Schreier figure of merit (FoM) of 185.8 dB.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic Instrumentation(OLD)Applied Quantum ArchitecturesMicroelectronic
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