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Phosphotriester synthesis of unprotected polydeoxyribonucleotides anchored to a polymeric support
No full textGoing Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Solid-phase synthesis of polynucleotides with defined sequences by the phosphotriester method based on the elongation of the chain in the 5' to 3'-end direction.
No full textThe phosphotriester solid phase method based on the elongation of the chain in the 5'- to 3'-end direction was used for the synthesis of polydeoxyribonucleotides of 16-18 units contg. all 4 bases. New deprotection procedures and the use of above ambient temp. for coupling reactions are described
Phosphotriester synthesis of unprotected polydeoxyribonucleotides anchored to a polymeric support
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Sinthesis of 1-(2-deoxy-3,5-di-O-acetyl-ß -D-ribofuranosyl)-4-chloro-5- methyl 2(1H) pyrimidinone
No full text3',5'-Diacetylthymidine (250 mg) was refluxed with SOCl2 in CHCl3 contg. DMF for 1.5 h to give 160 mg title nucleoside (I; R = Cl) (II). Structure of II was confirmed by NMR data and by its conversion into thymidine and 5-methyl-2'-deoxycytidine by treatment with aq. NaOH and concd. methanolic NH3, resp. Reaction of II with EtOH gave I (R = OEt). The mobility of Cl in the 4-position did not allow chem. deacetylation of II in satisfactory yield
Synthesis and characterization of a platinum (II) nucleoside complex linked through a Pt-C *-bond
No full textSynthesis and characterization of a platinum (II) nucleoside complex linked through a Pt-C *-bond
No full textPolymer supported synthesisof mixed polydeoxyribonucleotides through phosphotriester intermediates
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