1,720,991 research outputs found

    Hypertrichosis in a kidney-transplanted child: Dramatic regression after cyclosporin A was replaced by FK506

    No full text
    Hypertrichosis is commonly seen in patients who have received cyclospori A (CsA). We describe a kidney-transplanted child, treated with CsA, who showed severe hypertrichosis. Because of the serious cosmetic problem CsA was replaced by FK506, a potent immunosuppressant drug without hair growth-stimulating effects by oral administration. Massive loss of hair occurred 3 weeks after the beginning of treatment with FK506

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Full text link
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Sarcoidosi a primitiva localizzazione cutanea. Studio clinico-prognostico e istopatologico di 17 pazienti

    No full text
    We present the results of a clinical, prognostic and histopathological study of 17 patients with sarcoidosis primarily involving the skin. Our caselist consists of 17 Caucasian patients observed between 1969 and 1989: 4 were males and 13 females, aged 23 to 70 years, with a mean age of 49.8 years. The diagnosis was confirmed by histopathological examination. All patients were subjected to numerous laboratory and instrumental examinations. According to the spreading of the lesions, all patients were treated with intralesional triamcinolone acetonide or oral prednisone. Minimum follow-up was 2 years (range: 2-22 years). Sarcoidosis primarily involving the skin does not seem to show predilection for any region, being almost ubiquitarily present throughout the skin surface. In most of the patients the lesions were multiple and polymorphous. During follow-up 8 patients (1 male and 7 females) showed involvement of one or more extracutaneous organs: 7 patients were previously treated with oral prednisone. Systemic involvement appeared 2 to 5 years after hospitalization and affected lungs in 6 patients, lymphnodes in 5, and eye, liver and bones in 1 patient each. On the basis of our results, sarcoidosis primarily involving the skin is not necessarily followed by systemic involvement: this might be supported by systemic corticosteroids
    corecore