40 research outputs found

    Cooperación internacional en el área de las bibliotecas y de la información : el trabajo del Instituto Goethe y del servicio de bibliotecas e información internacional

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    The paper presents the work done by the Service of International Libraries and Information of the Goethe Institute and the experience in the countries in development process

    Premaxillary protrusion assessment by the maxillanasionmandible angle in fetuses with facial clefts

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    <p>Objective The aim of the study was to measure the degree of premaxillary protrusion in fetuses with orofacial clefts of various severities. Methods The maxillanasionmandible (MNM) angle was measured retrospectively on by multiplanar corrected volumes. Sixty-two fetuses with orofacial clefts and known outcome volumes of the fetal head were available. Results In 48 of the 62 cases, the MNM angle could be measured [mean gestational age 23 (range, 1830)weeks]. The mean MNM angle was normal in all nine cases with cleft lip and intact alveolar ridge (15.2 degrees; range, 12.5 degrees 16.9 degrees). In 24 cases with unilateral cleft lip with or without cleft palate (UCL/P), the mean MNM angle was 20.0 degrees (range, 13.326.2 degrees), being above the 95th percentile in 79% (n=19) and normal in 21% (n=5). In 14 bilateral cleft lip and palate (BCL/P) cases, the mean MNM angle was 26.5 degrees (range, 19.2 degrees 33.7 degrees) and above the 95th percentile in all cases. There was no difference in MNM angle between isolated clefts and clefts associated with other anomalies. In one case with a Tessier 4 cleft, the MNM angle was above the 95th percentile (25.2 degrees). Conclusion The premaxilla tends to protrude in both BCL/P as UCL/P cases. The degree of protrusion varies greatly, especially in the BCL/P group. (c) 2013 John Wiley & Sons, Ltd.</p>

    Unusual cause of sudden cardiac death: Basophilic degeneration of coronary arteries

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    Basophilic or mucoid degeneration of the intima in the coronary arteries is an extremely rare cause of premature atherosclerosis. An unusual case of fatal basophilic degeneration of the coronary arteries 142 days after delivery is reported. (C) 1996 Wiley-Liss, Inc

    Unusual cause of sudden cardiac death:Basophilic degeneration of coronary arteries

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    Basophilic or mucoid degeneration of the intima in the coronary arteries is an extremely rare cause of premature atherosclerosis. An unusual case of fatal basophilic degeneration of the coronary arteries 142 days after delivery is reported. (C) 1996 Wiley-Liss, Inc.</p

    Is 3D technique superior to 2D in Down syndrome screening? Evaluation of six second and third trimester fetal profile markers

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    ObjectiveThe objective of this article is to investigate whether in the clinical setting of second trimester ultrasound (US) investigations, 3D multiplanar correction prior to the measurement of Down syndrome (DS) facial markers (nasal bone length, prenasal thickness, fetal profile line, maxilla-nasion-mandible angle, prenasal thickness to nasal bone length ratio, and prefrontal space ratio) is superior to subjective judgment of a correct midsagittal plane by 2D technique. MethodsMeasurements were performed on 2D images and 3D volumes (corrected to the midsagittal plane), acquired during the same scanning session. ResultsAll six markers were measured in 105 datasets (75 of euploid fetuses and 30 of DS fetuses). The maxilla-nasion-mandible angle measured on 2D images was significantly larger than on 3D volumes (p ConclusionsNasal bone length, prenasal thickness, fetal profile line, prenasal thickness to nasal bone length ratio, and prefrontal space ratio can be confidently used as DS markers in second trimester US examinations performed by 2D US. (c) 2014 John Wiley & Sons, Ltd

    Maxilla-nasion-mandible angle: a new method to assess profile anomalies in pregnancy

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    Objectives To collect normative data and test the feasibility and reproducibility of measurement of the maxilla-nasion-mandible (MNM) angle between 16 and 36 weeks' gestation and its diagnostic ability in a group of pathological cases. Methods The MNM angle is defined as the angle between the intersection of the maxilla-nasion and mandible-nasion lines in the exact mid-sagittal plane. After assessing reproducibility, the MNM angle was measured in 3D volumes in 241 fetuses cross-sectionally and in 11 fetuses longitudinally. The MNM angle was then tested in 18 pathological cases with facial malformations or syndromes with specific facial features. Results The MNM angle could be measured in 92.3% of normal fetuses. Intra- and interobserver intraclass correlation coefficient (ICC) variability was 0.92 and 0.81, respectively. The difference between paired measurements performed by one or two observers was less than 2.5 degrees and 3.6 degrees, respectively in 95% of the cases. The mean MNM angle was 13.5 degrees and did not change significantly during pregnancy (r = -0.08, P = 0.25). The MNM angle was above the 95(th) centile in all cases of retrognathia and maxillary alveolar ridge interruption. The MNM angle was below the 5(th) centile in Apert syndrome, thanatophoric dysplasia and in two of the three Down syndrome cases. Conclusions The feasibility and reproducibility of measurement of the MNM angle is good. The MNM angle can be used to evaluate the convexity of the fetal profile by enabling an objective assessment of the anteroposterior relationship of the jaws and it may therefore be of help in the diagnosis of retrognathia, maxillary alveolar ridge interruption and flat profile. Copyright (C) 2011 ISUOG. Published by John Wiley & Sons, Ltd
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