9,338 research outputs found
Cloud hosted business-data driven BI platforms
No full textBusiness Intelligence in Platform as a Service (PaaS) for information analysis is increasingly being considered for its applications in the enterprises because of its advantages. It is widely used for Data Analysis, Customer Churn Prediction, etc. However, the challenges that the traditional BI platform faces includes the tremendous volume of data, high time and space complexity of algorithms and the incompatibility in the Integration to the BI tools. Thus instead of having traditional Data Warehouses for storage which require high maintenance and storages, companies are moving towards more efficient cloud based storages
Assessment and Prevention Of Falls In Elderly: Nurses’ Role
No full textFalls in elderlies has been a major concern in geriatric care. One out of three elderlies have
been falling every year and the many more elderlies are constantly at risk of falls. These falls
lead to serious injuries like hip fractures and build sense of fear in elderlies, which limit their
activities and degrade their quality of life.
There has been seen a huge need to enhance the skill and knowledge of the present and future
nurses to ensure that they are professionally and personally capable to identify the risk factors
and plan prevention strategies accordingly.
Literature review has been used in this thesis to find out the possible assessment methods to
assess the risk factors of falls in elderly, the vulnerable groups of elderlies who have higher
chances of falling. In addition, the possible falls prevention strategies have been studied and
laid out in this thesis.
A total of 11 relevant articles were obtained from a reliable database search.
The contents of the thesis have been categorized into distinct assessment and prevention
headings for ease of reading and finding required information. In the conclusion end, the author has presented his own ideas and discussed the additional need for safety of elderlies
Tight Lower Bounds for Approximate & Exact k-Center in Rd
No full textIn the discrete k-Center problem, we are given a metric space (P, dist) where \textbarP \textbar = n and the goal is to select a set C ? P of k centers which minimizes the maximum distance of a point in P from its nearest center. For any ? > 0, Agarwal and Procopiuc SODA'98, Algorithmica'02 designed an (1 + ?)-approximation algorithm1 for this problem in d-dimensional Euclidean space2 which runs in O(dn log k) + ( k? )O(k1-1/d) · nO(1) time. In this paper we show that their algorithm is essentially optimal: if for some d = 2 and some computable function f, there is an f(k)· ( 1? )o(k1-1/d) ·no(k1-1/d) time algorithm for (1 + ?)-approximating the discrete k-Center on n points in d-dimensional Euclidean space then the Exponential Time Hypothesis (ETH) fails. We obtain our lower bound by designing a gap reduction from a d-dimensional constraint satisfaction problem (CSP) to discrete d-dimensional k-Center. This reduction has the property that there is a fixed value ? (depending on the CSP) such that the optimal radius of k-Center instances corresponding to satisfiable and unsatisfiable instances of the CSP is \< 1 and = (1 + ?) respectively. Our claimed lower bound on the running time for approximating discrete k-Center in d-dimensions then follows from the lower bound due to Marx and Sidiropoulos SoCG'14 for checking the satisfiability of the aforementioned d-dimensional CSP. As a byproduct of our reduction, we also obtain that the exact algorithm of Agarwal and Procopiuc SODA'98, Algorithmica'02 which runs in nO(d·k1-1/d) time for discrete k-Center on n points in d-dimensional Euclidean space is asymptotically optimal. Formally, we show that if for some d = 2 and some computable function f, there is an f(k) · no(k1-1/d) time exact algorithm for the discrete k-Center problem on n points in d-dimensional Euclidean space then the Exponential Time Hypothesis (ETH) fails. Previously, such a lower bound was only known for d = 2 and was implicit in the work of Marx IWPEC'06. © Rajesh Chitnis and Nitin Saurabh; licensed under Creative Commons License CC-BY 4.
Improvement of hydrogen storage characteristics of carbon nanostructural variants admixed nano MgH2
No full textIn the present work, we have synthesized and studied the catalytic effect of different carbon nanostructures (CNSs) on the absorption kinetics, decomposition temperature of MgH2. Ball-milling was used to reduce the particle size of MgH2 and CNS catalysts were used to enhance the hydrogen storage properties at lower temperatures. In particular, 2wt% twisted carbon nanofibres (TCNF) admixed ball-milled MgH2 (MgH2-2TCNF) corresponds to better hydrogenation/ dehydrogenation behaviour. The commencement of H-desorption temperature is ∼420 ?C for pure MgH2, ∼ 330 °C for TCNF admixed MgH2, which is further lowered to 297 °C for TCNF admixed ball-milled MgH2. Thus, desorption temperature gets more than 125 °C lower compared to commercial MgH2. After the desorption, Mg- 2TCNF (ballmilled) shows 5.03 wt% absorption as compared to 3.05 wt% for the ball milled MgH2 in the first 10 minutes even at 180 °C and an applied pressure of 2MPa. Whereas in the case of 2TCNF admixed MgH2 it shows absorption of 4.28 wt% at a higher temperature 300 °C and an applied pressure of 2 MPa. The improved properties originate due to the CNSs catalyst and nanostructure of MgH2 introduced during ball milling in hydrogen pressure
Biocatalytic route to C-3?-azido/-hydroxy-C-4?-spiro-oxetanoribonucleosides
No full textThe lipase, Novozyme®-435, exclusively deacetylates the 5-O-acetyl over 4-C-acetyloxymethyl group of almost identical reactivity in 5-O-acetyl-4-C-acetyloxymethyl-3-azido-3-deoxy-1,2-O-isopropylidene-?-D-ribofuranose that led to the development of first and efficient synthesis of 3?-azido-/3?-amino-C-4?-spiro-oxetanoribonucleosides T, U, C and A in 20–24% overall yields. The X-ray study on the compound obtained by tosylation of lipase-mediated monodeacetylated product unambiguously confirmed the point of diastereoselective monodeacetylation on diacetoxy-azido-ribofuranose derivative. The capability of Novozyme®-435 for selective deacylation of 5-O-acetyl group in 5-O-acetyl-4-C-acetyloxymethyl-3-O-benzyl-1,2-O-isopropylidene-?-D-ribofuranose recently discovered by us has been successfully used for the synthesis of C-4?-spiro-oxetanoribonucleosides A and C in good yields. These results clearly indicate that the broader substrate specificity and highly selective capability of Novozyme®-435 for carrying out acetylation/deacetylation reactions can be utilized for the development of environment friendly selective methodologies in organic synthesis
Small sample multiple testing with application to cDNA microarray data
No full textMany tests have been developed for comparing means in a two-sample scenario.
Microarray experiments lead to thousands of such comparisons in a single study. Several
multiple testing procedures are available to control experiment-wise error or the false
discovery rate. In this dissertation, individual two-sample tests are compared based on
accuracy, correctness, and power. Four multiple testing procedures are compared via
simulation, based on data from the lab of Dr. Rajesh Miranda. The effect of sample size
on power is also carefully examined. The two sample t-test followed by the Benjamini
and Hochberg (1995) false discovery rate controlling procedure result in the highest
power
Assessing the Vasculature Changes in Murine Fetal Brain Upon Alcohol Exposure
No full textFetal Alcohol spectrum disorder (FASD) refers to a broad spectrum of abnormalities that arise due to prenatal alcohol exposure (PAE). The severity of the abnormality depends on the amount of alcohol consumed and period of consumption during gestation. A large number of women continue to consume alcohol even during the second trimester of pregnancy, a critical period for fetal neurogenesis and angiogenesis. OCT is an optical analog of ultrasound. 3D non-invasive imaging technique with high spatial resolution. OCT has shown to be extremely useful in embryonic imaging. Speckle variance OCT (SVOCT), is a functional extension of OCT that has been used to study vasculature development in embryos. We use SVOCT, to detect vasculature changes in the embryonic brain in utero, minutes after maternal alcohol consumption. The results show that there is a decrease in fetal vessel diameter within the first 10 minutes and it persisted for 45 minutes after maternal alcohol consumption, indicating that ethanol is a possible vasoconstrictor on the fetal brain. This project was completed with contributions from Rajesh C. Miranda from the Neuroscience and Experimental Therapeutics, Texas A&M Health Science Center.Biomedical Engineering, Department ofHonors Colleg
Evaluating changes in murine fetal brain vasculature due to maternal nicotine exposure using in utero optical coherence tomography
No full textNicotine is a commonly used substance of abuse during pregnancy. Previous research has shown that prenatal nicotine exposure (PNE) is harmful to a fetus. PNE is known to cause intrauterine and postnatal growth restriction, decrease in head circumference and biparietal diameter, and perinatal mortality and morbidity. Evidence of negative influences of nicotine on brain development has been seen in humans too. It is unknown whether the relationship between maternal smoking and behavior problems is due to physical brain deficits caused by nicotine. In this study, we use optical coherence tomography (OCT), a noninvasive optical imaging modality with high spatial and temporal resolution to image the changes in fetal brain vasculature caused due to maternal nicotine exposure. We use a functional extension of OCT called correlation mapping optical coherence angiography (cm-OCA) to image microvasculature in the fetal brain, in utero. Pregnant mice at 14.5 days post coitum were anesthetized and placed on a heated surgical platform. Abdominal fur was removed, and a small incision was made to expose the uterine horn for imaging. After initial cm-OCA measurements, the mother was administered nicotine via intragastric gavage, at a dose of 1mg/kg. Subsequent measurements were taken for a period of 45 minutes at 5-minute intervals. A drastic decrease in parameters quantifying vasculature was seen within 45 minutes of maternal nicotine exposure during the second trimester equivalent period. This project was completed with contributions from Rajesh C. Miranda from Texas A & M University College of Medicine.Health and Human Performance, Department ofHonors Colleg
FIGURE 2. Memecylon pachaimalayanum—a. Tree, b. Twig, c in Memecylon pachaimalayanum (Melastomataceae)-a new species from the Eastern Ghats of Tamil Nadu in India
No full textFIGURE 2. Memecylon pachaimalayanum—a. Tree, b. Twig, c. Floral buds in axillary fascicle, d. Axillary fascicles in full blossom, e. Immature fruits, f. Mature fruit, g. A portion of cleared leaf, showing narrowly filiform, unbranched, often mixed with spheroidal sclereids. Photographs: C. Rajasekar and R. Rajesh.Published as part of Rajesh, R., Viswanathan, M.B. & Silambarasan, R., 2021, Memecylon pachaimalayanum (Melastomataceae)-a new species from the Eastern Ghats of Tamil Nadu in India, pp. 69-76 in Phytotaxa 496 (1) on page 72, DOI: 10.11646/phytotaxa.496.1.3, http://zenodo.org/record/542349
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