129 research outputs found

    Intramedullary spinal cord metastasis from an adenoid cystic carcinoma of the external auditory canal: case report

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    Intramedullary spinal cord metastases (ISCMs) are rare and no cases of ISCM from an adenoid cystic carcinoma (ACC) of the external auditory canal (EAC) have been reported

    SEM, TEM, and IHC Analysis of the Sinus Node and Its Implications for the Cardiac Conduction System

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    More than 100 years after the discovery of the sinus node (SN) by Keith and Flack, the function and structure of the SN have not been completely established yet.The anatomic architecture of the SN has often been described as devoid of an organized structure; the origin of the sinus impulse is still a matter of debate, and a definite description of the long postulated internodal specialized tract conducting the impulse fromthe SN to the atrioventricular node (AVN) is still missing. In our previously published study, we proposed a morphologically ordered structure for the SN. As a confirmation of what was presented then, we have added the results of additional observations regarding the structural particularities of the SN. We investigated the morphology of the sinus node in the human hearts of healthy individuals using histochemical, immunohistochemical, optical, and electron microscopy (SEM, TEM). Our results confirmed that the SN presents a previously unseen highly organized architecture

    Benign cystic mesothelioma in a male patient: surgical treatment by the laparoscopic route.

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    We report a case of a benign cystic mesothelioma in a 44-year-old man. The patient was asymptomatic, and the cystic formation was discovered by chance in the course of ultrasonography for urological disorders. Benign cystic mesothelioma is a rare pathology, and only 19 cases have been described in male patients. The differential diagnosis versus other cystic diseases can only be defined histologically and is of critical importance to clinical management. Surgery is mandatory for both diagnosis and treatment. In the case reported here, a minimally invasive laparoscopic approach allowed not only histological diagnosis of benign cystic mesothelioma, but also its surgical treatment by the same route

    Retained medullary cord confirmed by intraoperative neurophysiological mapping.

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    Introduction: A retained medullary cord (RMC) is a rare dysraphic malformation, recently described as a late arrest of secondary neurulation. RMC is also a severely tethering lesion. The critical role of intraoperative neurophysiology to safely manage a RMC has been only anecdotally reported. Case report: We describe the case of a RMC in a 1.5-year-old child with Currarino syndrome. At surgery, an apparently normal-looking spinal cord, stretched and tethered by a lipoma to the level of S2-S3, was observed. The border between the functional conus and the non functional RMC was defined through neurophysiological mapping. The cord was sharply interrupted at this level and untethered. A specimen was sent for pathology, which confirmed the presence of glial and neural elements. The post-operative neurological exam was normal. Conclusion: Neurosurgical procedure for RMC should only be rendered with intraoperative neurophysiological mapping, as the anatomical judgment would not suffice to allow a safe cutting of these “normal-looking” neural structures

    Prognostic factors in childhood intracranial ependymomas: the role of age and tumor location

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    Despite several clinical reports on intracranial ependymomas in children, the factors which affect prognosis, and the possibility that certain combinations of factors might limit survival, are still a matter of debate. Between 1976 and 1996 we operated on 35 children with intracranial ependymomas. Postoperative irradiation was given to 27 patients, with associated chemotherapy in 6 cases. Mean follow-up was 62 months. In 12 patients a 5-year follow-up was possible. In October 1996, 18 patients (51.4%) were still alive, the longest disease-free follow-up being 20 years, and the shortest 8 months. We analyzed the prognostic relevance of eight factors. For each factor, different subgroups were distinguished and compared as follows: age at diagnosis (<4 vs. >/=4 years), sex, tumor location (supratentorial vs. infratentorial), tumor size (<4 vs. 4-7 vs. >7 cm), surgical removal (total vs. subtotal), histology (low-grade vs. anaplastic), morphology (solid vs. cystic), adjuvant therapies (treatment vs. no treatment). Two-way contingency tables were made to identify associations between variables. The only significant association was between age and tumor location (p = 0.022): in children under 4, tumors were almost invariably located in the posterior fossa (9 out of 10 cases) with a clear preference for the lateral recess (8 cases). Other correlations were not significant. Kaplan-Meier survival curves were compared to assess the prognostic relevance of each factor. Survival was significantly lower for children under 4, for those with posterior fossa tumors, and for patients with residual tumor (p < 0.05). A multivariate analysis compared variables which significantly affected survival, revealing that age is the most important factor affecting prognosis (p < 0.05), while tumor location and surgical removal do not add any significance to the effect of age on survival. We conclude that age has the strongest prognostic relevance in childhood intracranial ependymomas, while the effect of tumor location on survival may be related to the high incidence of lateral recess ependymomas in younger children

    Expressed attitudes and ethnic identity in Italy: A comparison of two regional communities (Veneto and Sardinia)

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    International audienceAlthough Italian is nowadays the national language shared by all Italians, regional languages still have a wide diffusion within the local communities (Tosi, 2001). Politically, the Italian government has recognized some of these languages and communities officially. Sardinia and Veneto's communities and languages benefit from a different status. In fact, Sardinian language has been officially given the status of a minority language (national law 482/1999 and Sardinian regional law 26/ 1997) whereas Veneto does not enjoy such an official recognition despite its socio-historical and prestigious literary and political heritage (Feltrin, 2003; Tufi, 2013). The link between linguistic and community identity is an important element contributing to expressions of language attitudes within Italy. Moreover, these have significant repercussions on the political as well as the social debates, which can go from nationalist pro-Italian to independentist discourse. Our study is based on the observation of these expressions of language attitudes found within the public spheres, mainly in Internet forums, social networks and public sites as Youtube (see also Depau & Ghimenton, 2009). We analyze in which circumstances Italy is acknowledged as the nation state or when it is perceived as the imperialist figure. From the linguistic side, we will explore whether or not Italian is perceived as a means of implementing such imperialism to the detriment of the local communities' languages. For example, the speakers' designation of a local variety as a "dialect" or as a "language" is a possible start to the exploration of the linguistic identity. The overarching aim of the study is to compare Sardinian with Veneto in order to examine whether the differing status has an impact on the identity values speakers assign to their local languages. The observations from this comparative study may provide elements of further discussion on Italy's sociolinguistic situation and on the role of Internet on the diffusion of language ideologies. References: Depau, G., & Ghimenton, A. (2009). Internet and minority languages: a study on Sardinian. In S. Pertot, T. Priestly, & C. H. Williams (eds), Rights, promotion and integration issues for minority languages in Europe (p. 216‑226). Palgrave Macmillan. Feltrin, P. (2003). L'uso del dialetto: immagini della lingua locale presso i cittadini veneti. In G. Marcato (ed.), Italiano. Strana lingua (p. 45‑58). Padova: Unipress. Tosi, A. (2001). Language and Society in a Changing Italy. Multilingual Matters. Tufi, S. (2013). Language Ideology and Language Maintenance: The Case of Sardinia. International Journal of the Sociology of Language (p. 213-219)

    Expressed attitudes and ethnic identity in Italy: A comparison of two regional communities (Veneto and Sardinia)

    No full text
    International audienceAlthough Italian is nowadays the national language shared by all Italians, regional languages still have a wide diffusion within the local communities (Tosi, 2001). Politically, the Italian government has recognized some of these languages and communities officially. Sardinia and Veneto's communities and languages benefit from a different status. In fact, Sardinian language has been officially given the status of a minority language (national law 482/1999 and Sardinian regional law 26/ 1997) whereas Veneto does not enjoy such an official recognition despite its socio-historical and prestigious literary and political heritage (Feltrin, 2003; Tufi, 2013). The link between linguistic and community identity is an important element contributing to expressions of language attitudes within Italy. Moreover, these have significant repercussions on the political as well as the social debates, which can go from nationalist pro-Italian to independentist discourse. Our study is based on the observation of these expressions of language attitudes found within the public spheres, mainly in Internet forums, social networks and public sites as Youtube (see also Depau & Ghimenton, 2009). We analyze in which circumstances Italy is acknowledged as the nation state or when it is perceived as the imperialist figure. From the linguistic side, we will explore whether or not Italian is perceived as a means of implementing such imperialism to the detriment of the local communities' languages. For example, the speakers' designation of a local variety as a "dialect" or as a "language" is a possible start to the exploration of the linguistic identity. The overarching aim of the study is to compare Sardinian with Veneto in order to examine whether the differing status has an impact on the identity values speakers assign to their local languages. The observations from this comparative study may provide elements of further discussion on Italy's sociolinguistic situation and on the role of Internet on the diffusion of language ideologies. References: Depau, G., & Ghimenton, A. (2009). Internet and minority languages: a study on Sardinian. In S. Pertot, T. Priestly, & C. H. Williams (eds), Rights, promotion and integration issues for minority languages in Europe (p. 216‑226). Palgrave Macmillan. Feltrin, P. (2003). L'uso del dialetto: immagini della lingua locale presso i cittadini veneti. In G. Marcato (ed.), Italiano. Strana lingua (p. 45‑58). Padova: Unipress. Tosi, A. (2001). Language and Society in a Changing Italy. Multilingual Matters. Tufi, S. (2013). Language Ideology and Language Maintenance: The Case of Sardinia. International Journal of the Sociology of Language (p. 213-219)

    Extracapillary proliferative glomerulonephritis and pulmonary purpura in a patient with rheumatoid arthritis treated with gold salts

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    Extracapillary proliferative glomerulonephritis and pulmonary purpura in a patient with rheumatoid arthritis treated with gold salt
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