73 research outputs found
“La relazione terapeutica e prospettiva evolutiva in psicoanalisi. Sviluppi recenti del paradigma freudiano"
No full textUno degli assunti principali della psicopatologia evolutiva è che le esperienze relazionali vissute a partire dalla prima infanzia esercitano un'influenza rilevante sullo sviluppo della personalità; da qui derivano l'interesse per l'influenza esercitata dai modelli di funzionamento dell'infanzia sui modelli di funzionamento dell'adulto, e l'attenzione rivolta all'influenza dei modelli di funzionamento presenti e delle circostanze attuali, tenendo in considerazione il fatto che le relazioni successive possono modificare i modelli di funzionamento appresi nell'età evolutiva. L'orientamento evolutivo assume un ruolo chiave all'interno della concezione della relazione terapeutica, in cui possono funzionare come dimensioni silenti i motori fondamentali dello sviluppo (attività, autoregolazione, adattamento sociale, monitoraggio affettivo, assimilazione cognitiva), il cui processo può riattivare in senso trasformativo una forma peculiare di esperienza evolutiva il cui prototipo è la responsività contingenete caratterizzante la relazione madre-bambino
Allergen-specific immunoglobulin E in the skin and nasal mucosa of symptomatic and asymptomatic children sensitized to aeroallergens.
No full textOncocytic nonsecretory multiple myeloma. A clinicopathologic study of a case and review of the literature.
No full textWe report on a morphologic variant of multiple myeloma, identified in a 39-year-old man, with osteolytic lesions in two ribs and three lumbar vertebrae. Serum electrophoresis was normal and immunofixation of serum and urine was negative. Histologic examination of a resected rib revealed a homogeneous population of neoplastic plasma cells with granular and eosinophilic cytoplasm. Immunohistochemical stains showed monoclonality for lambda light chain and negativity for all heavy chains. At the ultrastructural level, the cytoplasm of the neoplastic plasma cells was almost totally occupied by round and elongated mitochondria, pushing the rough endoplasmic reticulum to the periphery. To the best of our knowledge, only two similar cases have been reported in the literature so far. The usefulness of obtaining a clinicopathologic correlation for the behaviour of this extremely rare variant of multiple myeloma is discussed
Sugarcane biomass estimate based on sar imagery: A radar systems comparison
No full textSBAM (Satellite Based Agricultural Monitoring) is a project funded by Italian Space Agency in the framework of Italian-Kenya cooperation. The project has four main objectives: a) to produce an updated map of the agricultural areas for Kenya based on Landsat 8 and Sentinel 2 imagery; b) to develop an automatic monitoring system able to classify agricultural areas and detect land use changes; c) to develop and deliver to the Kenyan partner of the project a system capable to download and process automatically Landsat8, Sentinel2, MODIS and MSG/SEVIRI images by providing standard products (vegetation indices, statistics, temporal analysis, etc.); d) to provide a tool for assessing changes in the agricultural area stability and crop yield. and study the feasibility of a tool capable to forecast crop yields. The paper is devoted to describe the activity carried out in the field of forecasting crop yield by using biomass estimate based on SAR images. The results obtained by using images acquired by X-band (Cosmo-Skymed), C-Band (Sentinel-1) and L-band (PALSAR) systems on a study area devoted to sugarcane will be described
Development of a vegetation damage severity index based on hyperspectral sensor data
No full textThe SAP4PRISMA (Development of algorithms and products for supporting the PRISMA mission) project is one of the five research projects funded by ASI (Italian Space Agency) with the objective to develop applications capable of suitably exploiting the data acquired by the satellite hyperspectral sensor PRISMA. PRISMA (PRecursore IperSpettrale della Missione Applicativa) is an earth observation system combining a hyperspectral sensor with a panchromatic medium-resolution camera. The mission, fully supported by the Italian Space Agency (ASI), is de-voted to Earth Observation and Remote Sensing Research to answer to the users increasing de-mand of accurate quantitative information about the Earth system. SAP4PRISMA project is focus-ing its research activities only on those geophysical parameters/applications/products that are suit-able for the characteristics of the mission and in perspective for further international hyperspectral missions (EnMAP, HyspIRI, etc.). The project is structured in interconnected research activities aimed at consolidating the methodological issues for retrieving geophysical and agro-environmental parameters to be used as inputs for the development of innovative complex prod-ucts (e.g., nitrate leaching, land degradation and fuel maps, etc.). The products proposed in the frame work of the SAP4PRISMA project regard: (a) land degradation and vegetation status, (b) products development for agricultural areas, (c) management and monitoring of natural and in-duced hazards. Regarding the application of PRISMA for the management and monitoring of natu-ral and anthropogenic hazards, we focus on the assessment of the damage severity and mainly on the effects of fire in vegetated areas interested by a fire. Moreover, project goal is to develop an index that, in the presence of an area where the vegetation shows a sharp decline, is able to under-stand the causes, that may not necessarily be linked to the occurrence of a fire (e.g., oil spills, floods, etc.). This paper aims at showing the results reached up-to-now in the process of develop-ing such an index called DSI (Damage Severity Index)
Satellite Hyperspectral Remote Sensing Potential for Vegetation Cover Mapping in a Fragmented Ecosystem: Pollino National Park, Italy
No full textInnovative Gluten-Free Fusilli Noodle Formulation: Leveraging Extruded Japanese Rice and Chickpea Flours
No full textBackground: The growing demand for nutritionally balanced, gluten-free products has encouraged the development of innovative formulations that deliver both sensory quality and functional benefits. Combining rice and legume flours offers promising alternatives to mimic gluten-like properties while improving nutritional value. This study aimed to develop a gluten-free fusilli noodle using extruded flours based on mixtures of Japanese rice (JR) and chickpea (CP) particles. Methods: A 23 factorial design with augmented central points was applied to evaluate the effects of flour ratio (X1, CP/JR, 20–40%), feed moisture (X2, 24–30%), and extrusion temperature (X3, 80–120 °C) on responses from process properties (PPs), extruded flours (EFs), and noodle properties (NPs). Results: Interaction effects of X3 with X1 or X2 were observed on responses. On PP, X1 at 120 °C reduced the mechanical energy input (181.0 to 136.2 kJ/kg) and increased moisture retention (12.0 to 19.8%). On EF, X1 increased water-soluble solids (2.3 to 4.2 g/100 g, db) and decreased water absorption (8.6 to 5.7 g/g insoluble solids). On NP, X1 also affected their cooking properties. The mass increase was greater at 80°C (140 to 174%), and the soluble-solids loss was greater at 120 °C (9.3 to 4.5%). The optimal formulation (X1–X2–X3: 40–30%–80 °C) yielded noodles with improved elasticity, augmented protein, and enhanced textural integrity. Conclusions: Extruded flours derived from 40% chickpea flour addition and processed under mild conditions proved to be an effective strategy for enhancing both the nutritional and technological properties of rice-based noodles and supporting clean-label alternative products for gluten-intolerant and health-conscious consumers
Association between MICA Gene Variants and the Risk of Hepatitis C Virus-Induced Hepatocellular Cancer in a Sicilian Population Sample
No full textThere are currently no biomarkers that predict hepatocellular carcinoma (HCC) risk in patients with hepatitis C virus (HCV)-related cirrhosis. We investigated the relationships among major histocompatibility complex (MHC) class I chain-related gene A (MICA) polymorphisms, plasma levels of soluble MICA (sMICA), and HCC risk in patients with HCV-related HCC. One hundred fifty-four HCV-related HCC patients, 93 HCV-related liver cirrhosis (LC) cases, and 244 healthy controls, all sampled from the native Sicilian population, were genotyped using the KASPTMsingle-nucleotide polymorphism genotyping method. The MICA rs2596542 polymorphism showed that the G/G genotype was significantly more frequent in HCC than control subjects and LC patients (p < 0.005). For MICA rs2596538 polymorphism, the C allele and C/C genotype were significantly more frequent in HCC than in controls and LC cases (p < 0.005), after controlling for potential confounders. These results demonstrate that MICA rs2596542G/G, and particularly the rs2596538C/C polymorphism, are associated with the risk of developing HCV-related HCC in a Sicilian population sample. Importantly, using a machine learning classifier, we found that "age" and either rs2596542 or rs2596538 were important discriminating factors for patients with LC and HCC. Finally, sMICA levels significantly increased during HCV-related liver disease progression, while a significant relationship between both rs2596542 and rs2596538 genotypes and sMICA plasma levels was identified in patients with LC and HCC. In summary, the MICA rs2596538 and rs2596542 variants warrant further research for their clinical validity and utility in relationship to the risk of developing HCV-related HCC in independent populations
Genetics of rotator cuff tears: no association of col5a1 gene in a case-control study
No full textAbstract Background The incidence of RC tears increases with aging, affecting approximately 30 to 50% of individuals older than 50 years, and more than 50% of individuals older than 80 years. Intrinsic factors (age or gender), extrinsic factors (sports activity or occupation), and biological factors were identified in the onset and progression of RC tears. The attention in the study of aetiology of RC tendinopathy has shifted to the identification of gene variants. Genes encoding for proteins regulating the concentration of pyrophosphate in the extracellular matrix and genes encoding for fibroblastic growth factors, defensin beta 1 and estrogen-related receptor-beta were analyzed. However, only in one study the role of variants of collagen type V alpha 1 (col5a1) gene in RC tears was assessed. The objective of this study was to determine whether a col5a1 DNA sequence variant, rs12722 (C/T) was associated with rotator cuff (RC) tears in a case-control study. Methods The study included 93 Caucasian patients undergoing surgery for RC tears and 206 patients with no history and sign of RC disease as evaluated by MRI. Patients were divided into two groups. Group 1 included patients with RC tear diagnosed on clinical and imaging grounds and confirmed at the time of surgery. Group 2 (control group) included patients without history or clinical symptoms of RC disorders and with a MRI negative for RC disease. DNA was obtained from approximately 1.2 ml of venous blood using the MagCore extractor system H16 with a MagCore Genomic DNA Large Volume Whole Blood Kit (RBC Bioscience Corp., Taiwan). All study participants were genotyped for SNPs rs12722. Results We first estimated that our study had 92% power at p < 0.05 to detect a genetic effect size of 2.05 in the RT tears (93 individuals) and healthy population (206 individuals) cohorts, assuming a minor allele frequency for col5a1 variant rs12722 of 0.5707 in the Italian population (gnomAD frequency). No significant difference in allele and genotype frequencies was observed between RT tears patients and healthy controls. Similarly, no significant association was seen between the RT tears and healthy controls participants in the combined genotype distributions. Conclusion In conclusion, no correlations between the SNP rs12722 of col5a1 gene and RC tears susceptibility was found
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