1,721,067 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Directly compressed mini-tablets coated in a solid wall pan for the sustained release of drugs
No full textSustained release mini-tablets can be produced either as matrix or by coating the mini-tablets in a fluid bed apparatus. Until now the coating of mini-tablets in a pan has not been extensively utilised; however this process shows advantages over the fluid bed providing higher production capabilities, lower waste of coating materials and faster equipment cleaning time. The aim of this research was to investigate the possibility of manufacturing a sustained release multiple dosage form by coating in a solid wall pan mini-tablets produced by direct compression; theophylline was employed as a model drug and WAS, an innovative ready to use pigment dispersion, was tested to evaluate the possibility of reducing production time.
The results obtained showed that:
·mini-tablets having a high amount of theophylline, low friability and high crushing strength were obtained by direct compression
·a solid wall pan represents a suitable technique for mini-tablets coating
·the use of a ready to mix pigment dispersion represents a suitable method to shorten coating suspension preparation time.
Therefore a sustained release multiple dosage form was successfully manufactured by using a tablet press and a solid wall pa
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Process understanding of drying applied to wet granulation in single-pot equipment
No full textThe drying phase in single pot wet granulator-vacuum dryers has not been greatly investigated, however, this step is very important from an industrial manufacturing point of view expecially in terms of energy and time. According to the latest FDA guidance about Process Analytical Technologies (PAT), the most appropriate approach for optimizing pharmaceutical production involves process understanding.
The aim of this study was the process understanding of drying in a single pot granulator (Rotocube 60, IMA). In particular, the effect of three drying parameters (bowl temperature, vacuum and microwaves) on the granule characteristics (loss on drying, morphology, particle size, flowability and friability) of a placebo product (monohydrate lactose, corn starch and polyvinylpirrolydone as binder) was evaluated. The properties of the related tablets (uniformity of mass, crushing strength, friability, disintegration time) were also studied. The preliminary data obtained, using the above mentioned equipment and formulation, suggest that different drying conditions, which determine different drying times, do not significantly affect the technological characteristics of both granules and tablets. In conclusion, this result demonstrates a clear formulation robustness, giving the opportunity to find the shortest drying time pertinent to drying conditions once the process is scaled up to an industrial single pot granulator
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