349 research outputs found
Il Movimento di Studi per l'Architettura 1945-1961
No full textIl volume, attraverso l'attività e i documenti del Msa, restituisce e interpreta il complesso dibattito sull'architettura e la ricostruzione nella Milano del secondo dopoguerra
Imaging Ferromagnetic Tracers With An Ac Biosusceptometer
No full textThe aim of this work was to study the feasibility of obtaining images of the distribution of ferromagnetic tracers using an ac biosusceptometer (ACB). The images were generated by mapping the response of the ACB at short distances due to the presence of a ferrite powder dispersed in a planar gel matrix with different shapes. The ACB was scanned over the sample and the voltages generated by the variation in ferrite concentration were sampled. Methods to render and image the distribution of ferromagnetic particles were studied. The generalized Wiener parametric method gave the best results. The system has a potential to be used in functional images of the gastrointestinal tract where a moderate resolution is required. We conclude that this biomagnetic method can be successfully used to generate planar functional images of magnetic particles in the near field. © 2000 American Institute of Physics.71625322538Erol, R.A., Cherian, P., Smallwood, R.H., Brown, B.H., Bardhan, K.D., (1996) Physiol. Meas., 17, pp. A141Ikeya, M., Ishii, H., (1990) J. Magn. Reson., 88, p. 130Smith, C.M., Stevens, A.D., (1994) Br. J. Radiol., 67, p. 1186Roth, B.J., Sepulveda, N.G., Wikswo J.P., Jr., (1989) J. Appl. Phys., 65, p. 361Moreira, M., Murta, L.O., Baffa, O., (1994) Phys. Med. Biol., 39 A, p. 633Miranda, J.R.A., Baffa, O., Oliveira, R.B., Matsuda, N.M., (1992) Med. Phys., 19, p. 445Baffa, O., Oliveira, R.B., Miranda, J.R., Troncon, L.E.A., (1995) Med. Biol. Eng. Comput., 33, p. 353Oliveira, R.B., Baffa, O., Troncon, L.E.A., Miranda, J.R.A., Cambrea, C.R., (1996) Eur. J. Gastroent. Hepatol., 8, p. 491Miranda, J.R.A., Oliveira, R.B., Sousa, P.L., Braga, F.J.H., Baffa, O., (1997) Phys. Med. Biol., 42, p. 1791Daghastanli, N.A., Braga, F.J.H.N., Oliveira, R.B., Baffa, O., (1998) Physiol. Meas., 19, p. 413Forsman, M., Hultin, L., Abrahamsson, H., (1995) Biomagnetism: Fundamental Research and Clinical Applications. Studies in Applied Electromagnetics and Mechanics, 7, p. 739. , edited by C. Baumgartner, L. Deecke, G. Stroink, and S. J. Williamson Elsevier, AmsterdamBasile, M., Neri, M., Carriero, A., Casciardi, S., Comani, S., Del Gratta, C., Donate, L.G., Romani, G.L., (1992) Dig. Dis. Scie., 37, p. 1537Bruno, A.C., (1997) J. Appl. Phys., 82, p. 1Cruvinel, P.E., Cesareo, R., Crestana, S., Mascarenhas, S., (1990) IEEE Trans. Instrum. Meas., 39, p. 745Lim, J.S., (1990) Two-Dimensional Signal and Image Processing, , Prentice-Hall, Englewood Cliffs, NJJ. P. Wikswo, Jr., N. G. Sepulveda, and I. M. Thomas, Ref. 11, p. 789Tan, S., Ma, Y.P., Smith, I.M., Wikswo J.P., Jr., (1996) IEEE Trans. Magn., 32, p. 230Weber, E., (1951) Electromagnetic Fields: Theory and Applications, Mapping of Magnetic Fields, 1. , Wiley, New YorkSpiegel, M.R., (1990) Mathematical Handbook of Formulas and Tables, , McGraw-Hill, New YorkBruno, A.C., Costa Ribeiro, P., Von Der Wied, J.P., Symko, O., (1986) J. Appl. Phys., 59, p. 2584Vrba, J., Fife, A.A., Burbank, M., Weinberg, H., Bricket, P.A., (1982) Can. J. Phys., 60, p. 106
Contact imidazole activity against resistant bacteria and fungi
No full textThe activities of miconazole and miconazole sulphosalicylate were evaluated by a contact test using strains of Enterococcus faecalis and Escherichia coli and Candida spp selected for their resistance. The results showed that killing of the organisms occured within a few minutes. Imidazole activity required a medium of low electrical conductivity and a pH of 5.6. Greater sensitivity could be obtained with pretreatment of the microbial suspensions with sodium dioctylsulphosuccinate. Microorganisms tested in culture media with low electrical conductivity and at pH 5.6 showed enhanced sensitivity to azoles with MIC values about 20-30 times lower than those obtained using control media. Practical implications of the use of topical drugs are discussed. (C) 2001 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved
Single-incision laparoscopic adnexectomy in an obese patient with previous laparotomies
No full textNo case of single-incision laparoscopic surgery in obese patients who had previously undergone multiple midline vertical laparotomies has been described in the literature to date. Hence we report the first case of single-port laparoscopic salpingo-oophorectomy in an obese patient who was affected by a left adnexal mass and who had previously undergone 3 midline vertical laparotomies
Molecular genetics of bladder cancer: Targets for diagnosis and therapy
No full textTransitional cell carcinoma of the bladder is a common tumor. While most patients presenting superficial disease can be expected to do well following treatment, still many patients will return to our office with muscle invasive and metastatic disease. Survival in advanced bladder cancer is less than 50%. Tumors of similar histologic grade and stage have variable behavior, suggesting that genetic alterations must be present to explain the diverse behavior of bladder cancer. It is hoped that through the study of the subtle genetic alterations in bladder cancer, important prognostic and therapeutic targets can be exploited. Many new diagnostic tests and gene therapy approaches rely on the identification and targeting of these unique genetic alterations. A review of literature published on the molecular genetics of bladder cancer from 1970 to the present was conducted. A variety of molecular genetic alterations have been identified in bladder cancer. Oncogenes (H-ras, erbB-2, EGFR, MDM2, C-MYC, CCND1), tumor suppressor genes (p53, Rb, p21, p27/KIP1, p16, PTEN, STK15, FHIT, FEZI/LZTS1, bc10), telomerase, and methylation have all been studied in bladder cancer. Several have proven to be potentially useful clinical targets in the prognosis and therapy of bladder cancer such as staining for p53 and gene therapy strategies such as p53 and fezl. Clinical trials targeting HER2/neu and the EGFR pathways are underway. The UroVysion bladder cancer assay relies on FISH to detect genetic alterations in this disease. Continuing identification of the molecular genetic alterations in bladder cancer will enhance future diagnostic and therapeutic approaches to bladder cancer. Capitalizing on these alterations will allow early detection, providing important prognostic information and unique targets for gene therapy and other therapeutic approaches
TP53 gene mutations in gastric carcinoma detected by polymerase chain reaction/single-strand conformation polymorphism analysis of archival material.
No full textTP53 gene mutations, one of the most common alterations described in human tumors, have also been detected in gastric carcinoma, and shown to occur rather late in disease progression. A better assessment of the prognostic value of TP53 gene mutations can be obtained by examining archival material, as this allows stored cases with well-defined histories to be monitored. We performed immunohistochemical and polymerase chain reaction/single-strand conformation polymorphism (PCR-SSCP) analyses of formalin-fixed paraffin-embedded material from nine selected cases of gastric carcinoma at different pathological stages. PCR-SSCP analysis of TP53 exons 5-8 detected missense point mutations in two out of five immunostain(PAb1801)-positive tumors, and a deletion (allowing for a premature stop codon) in one of the remaining four immunostain-negative tumors. Thus, PCR-SSCP analysis represents a feasible strategy for the detection of TP53 alterations in archival material of gastric carcinoma cases
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