715 research outputs found
Admission hyperglycemia and outcome in ICU patients with sepsis
Get PDFStress hyperglycemia is a very common feature in the intensive care (ICU) setting and it is related to multiple causes that include inflammatory and neuro-endocrine derangements in critically ill patients, which lead to insulin resistance and high hepatic glucose output (1). The target for glucose management in this population and its relationship with the patients’ outcome is not clear, and results from literature are contrastin
Non-invasive assessment of ICP in children: advances in ultrasound-based techniques
Get PDFThe assessment of intracranial pressure (ICP) in children with neurological disease remains a cornerstone in their routine management. The quest for a reliable, reproducible and radiation-free non-invasive technique for assessing ICP in children remains somewhat of a holy grail for neurosurgery. This work assesses some of the recent advances in ultrasound-based techniques, addressing both novel processes and modifications aimed at improving the accuracy of existing techniques.acceptedVersio
Convolvulus supinus var. melliflorus Carine & Robba, comb. nov.
No full text2b. Convolvulus supinus var. melliflorus (Pau) Carine & Robba, comb. nov. Basionym: Convolvulus valentinus var. melliflorus Pau (1911: 6). Holotype: MOROCCO. Zeluan, Pau s.n., 2 May 1910 (MA!) Convolvulus suffruticosus var. sulfureus Battandier (1919: 61) ≡ C. valentinus var. sulfureus (Battandier) Maire & Wiczek in Maire (1934: 25). Holotype: Ducellier s.n., 1 May 1917 (MPU!) Convolvulus valentinus var. simulans Maire (1936: 27) ≡ Convolvulus valentinus f. simulans (Maire) Sauvage & Vindt (1954: 2). Lectotype (designated by Sa’ad, 1967): Nain 10, 15 June 1919 (MPU!). Convolvulus valentinus var. transiens Maire & Wilczek in Maire (1934: 25). Isotype: MOROCCO. Castellum Tazzougert, 1200 m, Maire & Wilczek s.n., 18 April 1933 (AL, MPU!) Convolvulus valentinus var. adpressipilis Maire & Wilczek in Maire (1934: 25) Isotype: MOROCCO. In pascuis deserti amnem Zerzef inter Esfoud et Bou-Denib, 950 m, Maire, & Wilczek s.n., April 1933 (P! MPU!). Convolvulus valentinus var. embergeri Sauvage & Vindt (1954: 2), nom. nud. Stems usually villous, rarely glabrous or glabrescent. Leaves ovate, narrowly elliptic or rarely deltoid, 10–25 mm long × 2–9 mm wide; base cuneate or truncate; apices acute or rarely obtuse; sparsely to densely villous on lower leaf surface, glabrous or glabrescent above. (fig. 1e) Distribution:— Morocco, extending northwards from the Western Sahara to the Beni Snassen mountains; outlying populations also occurring in Algeria (fig. 2c). Habitat:— Arid gravel, stony or sandy habitats. Phenology:— Flowering March–July(–August); fruiting June–July(–August?). Conservation:— Least Concern (IUCN 2001). Other specimens seen:— ALGERIA. Sidi-Maklouf, route de Laghirive, Chevallier s.n., 8 April 1897 (P); Laghouat, Chevallier 223, 12 April 1897 (P); Laghouat, col des sables, Chevallier s.n., 17 April 1897 (P); Laghouat, plaine entre l'Oued Mzi et le Dj. Mileb, Chevallier s.n., 17 April 1897 (P); AS 2: E. foot of Dj. Amour, 50 km from Laghouat to Aflou, Davis 58667, 3 June 1975 (BM); Bou-Saada (wilaya de M'Sida) a 2km au S d'Ain-Khermane et a environ 30km au N de Bou-Saada, Dubuis 13437, 3 May 1986 (RNG, MA, BC); Djebel Sahar, environs de Djelf(s)a, Prov. Alger, Reboud s.n., May 1854 (P); Ras-el-ma pres Bou Saada, Contantine [Bou Saada], Reboud s.n., 7 May 1865 (P). MOROCCO. Ouarzazate, pr. oppidium Tifoultout, Blanché, Fernández-Casas, Molero, Montserrat, & Romo 9664, 31 May 1985 (E). NW Sahara: Sand dune vegetation of Goulimina, Bramwell, Richardson & Murray 586, 2 April 1972 (RNG); Beni Snassen: 23 km from Uojda on road to Taza, Carine, Ait Lafkih, Rumsey & Rutherford 365, 16 June 2005 (BM, RNG, IAV); 49 km from Oujda on road to Taza. 1 km before road crosses Oued Bourdim. Carine, Ait Lafkih, Rumsey & Rutherford 368, 16 June 2005 (BM, RNG, IAV); 6 km E of Taourirt on Taourirt-El Ayoun Road. Carine, Ait Lafkih, Rumsey & Rutherford 370, 16 June 2005 (BM, RNG, IAV); Beni Snassen: 23 km W. from Oujda on road to Taza. Carine, Ait Lafkih, Rumsey & Rutherford 366, 16 June 2005 (BM, RNG, IAV); Sahara: El Abiod Sidi Cheikh, ravines, route de Gergville, Chevallier s.n., 9 May 1899 (P); Plateau de l'arid, N. de Midelt, Damblon 79/159, 24 June 1979 (RNG); ED. Goulmima to Ksar-es-Souk, Davis & Davis 49063, 4 April 1969 (BM, E); Ksar-es-Souk to Erfoud., Davis & Davis 49093, 5 April 1969 (BM, E); ED. Ziz Gorge (Ksar-es-Souk to Rich), Davis & Davis 49179, 7 April 1969 (BM, E); ED: 2 km NE of Goulmima, Else s.n, 1 April 1995 (RNG, BM); Gorges du Ziz, Else s.n., 6 Apil 1995 (RNG, BM); Ksar Es Souk, entre Er Rachidia y Midelt, Fernández Casas, Muñoz Garmendia, Susanna & Telleria FC7088, 18 June 1982 (RNG, MA); in lapidosis calcareis Atlantis Majorii orientalis propre Rich, Humbert s.n., April 1927 (MPU); Bou Denib: bords de l'oed Guir, 5–6 km from Bou Denib, Humbert s.n., April 1923, (P); R to Noulouya: Misour, Jahandiez 93, 28 April 1925 (BM, E, MA); R to Noulouya: Midelt, gorges de Oued Outat, Jahandiez 144, 2 May 1925 (BM); 51 km ENE of Ouarzazate, 8 km ENE of Skoura, on road to Boumalne du Dadès, Jury 14524, 24 March 1994 (RNG, BM); 121 km from Midelt along the road to Guercif, Jury 16928, 26 April 1995 (BM, RNG, MA); SE of Guercif, 1.8 km S of junction of Guercif - Oujda main road, Jury 16911, 26 April 1995 (BM, RNG, MA, BC); Prov. Er Rachida, road N. from Erfoud, 59 km from Rissani, 1 km N of Ksar Jdid, Jury 19114, 19 February 2002 (RNG); 89 km from Midelt on Azrou-Midelt road, just south of Boulojoul, Jury 19461, 30 May 2002 (RNG); Prov. Er Rachida, road N. from Erfoud, 36 km before Er Rachidia, above village of Ait Amira, Jury 19156, 19 February 2002 (RNG); Meski Spring, 11 km S.E. of Ksar-es-Souk, O. Ziz, Lambert 357, 20 April 1969 (BM); Prov d'Errachidia, Vallee de Ziz, Ksar Jdid (5 km au N. d'Aoufous, route 567 Errachidia-Erfoud, a env. 23 km du carrefour de la P32), Lambion & van den Sande 95/Ma/212, 14 March 1995 (RNG, MA); Prov. De Taza, Ighoudane, oued Boulajraf, Lambion & van den Sande 94/MA/176, 30 May 1994 (RNG); RICH (Errachiaouat), Lewalle 10526, 8 July 1982 (BM); Boudenit (Prov. Emachitie), Lewalle 13658, 3 April 1992 (BM); 10 km N de Midelt, Lewalle 9131, 2 July 1979 (P); Missour Gurcif, piste Moulaya, l'Hermite s.n., April 1939 (P); Beni-Ouziem, Maire & Wilczek s.n. (94112), 17 April 1933 (MA); propre Guercif, Maire & Wilczek s.n., 25 April 1933 (P, MPU); Bou-Denib-Salei, Maire & Wilczek 414, 17 April 1933 (MA); Teniet Zerzef (Tafilaet), Maire & Wilczek 312, 15 April 1933 (MA); Inter Erfoud et BenDenib, Maire & Wilczek s.n. (139502), 15 April 1933 (BC); In glareis torrentium vallei Dades inter Ikoura et Aït Yaga, Maire & Weiller 395, 21 June 1939 (MPU); Guercif, Carreterra a Outat-Oulad-el-Haj, a 4 km de Mahirija, Mateos 6809/95, 11 June 1995 (RNG); between Mertigmer and Mechra-Homadi 69 km from Nador, Mateos & Valdés BV636/93, 31 May 1993 (RNG, BC); Fes Missour- Aïn Guettara, plateau, Mordant 1100, 9 May 1969 (P); Guercif Tafrata, Mordant 1195, 14 May 1969 (P); Qsar-Es-Souq Outskirts of Midelt, on track to Cirque du Jaffar, Jbel Ayachi. Locality 6, OPTIMA ITER V 289, 10 June 1992 (RNG); Zeluan, Pau s.n. (94102), 2 May 1910 (MA); In montibus Largko/Sargho, Peltier s.n., 10 April 1939 (MPU); Mgoun/Haut Atlas oriental: vallei du Dadès en amour du Boumalne, Sauvage 12277, 1 April 1954 (MPU).Published as part of Carine, Mark A. & Robba, Lavinia, 2010, Taxonomy and evolution of the Convolvulus sabatius complex (Convolvulaceae), pp. 1-21 in Phytotaxa 14 on page 16, DOI: 10.11646/phytotaxa.14.1.1, http://zenodo.org/record/477870
FIGURE 2 in Taxonomy and evolution of the Convolvulus sabatius complex (Convolvulaceae)
No full textFIGURE 2. Distributions of taxa in the C. sabatius complex. (a) C. valentinus, (b) C. sabatius subsp. mauritanicus (open circles) and C. sabatius subsp. sabatius (closed diamonds), (c) C. supinus var. supinus (open circles) and C. supinus var. melliflorus (closed circles).Published as part of Carine, Mark A. & Robba, Lavinia, 2010, Taxonomy and evolution of the Convolvulus sabatius complex (Convolvulaceae), pp. 1-21 in Phytotaxa 14 on page 6, DOI: 10.11646/phytotaxa.14.1.1, http://zenodo.org/record/477870
Traumatic brain injury and translational research: pharmacological and nonpharmacological perspectives
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Ten rules for optimizing ventilatory settings and targets in post-cardiac arrest patients
No full textCardiac arrest (CA) is a major cause of morbidity and mortality frequently associated with neurological and systemic involvement. Supportive therapeutic strategies such as mechanical ventilation, hemodynamic settings, and temperature management have been implemented in the last decade in post-CA patients, aiming at protecting both the brain and the lungs and preventing systemic complications. A lung-protective ventilator strategy is currently the standard of care among critically ill patients since it demonstrated beneficial effects on mortality, ventilator-free days, and other clinical outcomes. The role of protective and personalized mechanical ventilation setting in patients without acute respiratory distress syndrome and after CA is becoming more evident. The individual effect of different parameters of lung-protective ventilation, including mechanical power as well as the optimal oxygen and carbon dioxide targets, on clinical outcomes is a matter of debate in post-CA patients. The management of hemodynamics and temperature in post-CA patients represents critical steps for obtaining clinical improvement. The aim of this review is to summarize and discuss current evidence on how to optimize mechanical ventilation in post-CA patients. We will provide ten tips and key insights to apply a lung-protective ventilator strategy in post-CA patients, considering the interplay between the lungs and other systems and organs, including the brain
Contrast-enhanced ultrasound imaging in detection of changes in cerebral perfusion.
No full textContrast-enhanced ultrasonography (CEU) is a non-invasive imaging technique that provides real-time, bedside information on changes in global and segmental organ perfusion. Currently, there is a lack of data concerning changes in the distribution of segmental brain perfusion in acute ischemic stroke treated by decompressive craniectomy. The aim of our case series was to assess the role of CEU after decompressive craniectomy in patients with acute ischemic stroke. CEU was performed in 12 patients at baseline and after any one of the following interventions was performed as dictated by the patient's clinical condition: vasoactive drug administration (in order to achieve cerebral perfusion pressure ≥70 mm Hg and mean arterial pressure <100 mm Hg for management of arterial blood pressure) and mild hyperventilation (carbon dioxide arterial pressure = 30-35 mm Hg). CEU was able to detect a significant variation in cerebral contrast distribution in both normal and pathologic hemispheres after induced hyperventilation (difference in time to peak [dTTP] = -38.4%), vasodilation (dTTP = -6.6%) and vasoconstriction (dTTP = +31.2%) (p < 0.05). CEU can be useful in assessing real-time cerebral perfusion changes in neurocritical care patients
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