196,032 research outputs found

    Chronic kidney disease

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    Chronic kidney disease is a condition that affects thousands of children all over the world, compromising their health and quality of life. Recent epidemiological studies have provided evidence suggesting that the number of patients is expected to grow. This growth can be attributed, on the one hand, to new emerging conditions predisposing to chronic kidney disease, such as low birth weight, prematurity, and obesity. On the other hand, huge progress has been made in the clinical management of children and infants with chronic kidney disease and end-stage renal disease, leading to a significant reduction in morbidity and mortality. As the natural evolution of chronic kidney disease is variable in children, a number of strategies (antihypertensive and anti-proteinuric therapies) aimed at slowing down its progression have been implemented. Current research is pointing in the direction of genetic and target therapies against the molecular-inflammatory process behind the loss of renal function. Growth failure and cardiovascular complications represent the greatest challenges for pediatric nephrologists. The gold standard therapy is preemptive transplantation and more advanced dialysis modalities are now widely available also for small children and infants

    A questionnaire survey of radiological diagnosis and management of renal dysplasia in children

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    BackgroundThe entity called renal dysplasia is considered to be a frequent cause of chronic kidney disease in children. Formally, the entity is defined by histological parameters. In current nephrology practice, however, the appearance of kidneys on ultrasound scanning is often used as a basis for the diagnosis.MethodsThe European Society for Paediatric Nephrology Working Group on Congenital Anomalies of the Kidney and Urinary Tract hypothesised that the current diagnostic approach with regard to renal dysplasia was not homogeneous. Accordingly, we here report the results of a survey targeting pediatric nephrologists with 12 questions regarding their perceptions of the ultrasonographic characteristics of renal dysplasia and further tests that they might undertake.ResultsOf almost 1200 physicians who successfully received the invitation, 248 from 54 countries completed the survey. There was a notable lack of homogeneity regarding the ultrasonographic diagnosis of renal dysplasia and also of follow up tests, including genetic testing and further radiology.ConclusionsBased on the responses to this large survey, a picture emerges of nephrologist’s current clinical practise with a focus on renal dysplasia. The Working Group consider that these results serve as an important sounding board that can inform more definitive recommendations regarding the challenges to clinical diagnosis and diagnostic follow-up of the this important entity

    Dr. Duane M. Jackson, Morehouse College, July 2011

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    This video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer

    "Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.

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    "Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states. By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement. To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Dr. Glendon Swarthout

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    Hosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness
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