1,720,979 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Growth response to appropriate medical intervention in a cohort of children born small for gestational age
No full textBackground
Children born small for gestational age (SGA) often experience growth retardation and are at higher risk of long-term health issues. Growth hormone (GH) treatment is considered for SGA children who fail to catch up to normal growth percentiles. However, response to treatment varies, and predictive markers for successful catch-up growth remain unclear.
Methods
We conducted a retrospective observational study of 52 SGA patients treated at a pediatric endocrinology unit. Patients were categorized based on "medical intervention" (GH treatment) or "wait and see" approaches. Outcome groups were defined as "good catch-up" (ΔHt > 0.5 SD or HV > 1 SD) or "poor catch- up" one year after follow-up initiation. We analyzed clinical, biological, and radiological data to identify potential predictive markers.
Results
Patients receiving "medical intervention" achieved a higher rate of "good catch- up" (48.3%) than those on "wait and see" (13.0%). "Good catch-up" patients had lower growth velocity at baseline (T0) compared to "poor catch-up" patients (-1.5 SD vs. -0.3 SD; p = 0.015). Moreover, in the “medical intervention” group, "good catch-up" patients were below their genetic target height at T0 (p = 0.002) and had significantly lower IGF-BP3 levels at T-1 (p = 0.006).
Conclusion
Our study suggests that a greater growth deficit in children born SGA may lead to a more favorable response to GH treatment. Lower IGF-BP3 levels at baseline and reduced growth velocity prior to treatment initiation may serve as potential predictive markers for successful catch-up growth
Frequency of associated features in 46,XY and 46,XX Differences of sexual development (DSD) patients
No full textContext: The focus of care in differences of sexual development (DSD) is mainly directed towards sex and gender development. Associated features are scarcely described. Widening the phenotypic spectrum of DSD might help to elucidate molecular aetiologies.
Objective: to determine the frequency of syndromic forms and to describe the associated features in 46,XY and 46,XX DSD patients.
Patients and methods: retrospective cohort study of patients with 46,XY and 46,XX DSD that have been admitted in the CHUV endocrinology and diabetology unit, the DSD multidisciplinary consultation or the paediatric urology unit and who were born before 01.01.2021.
Results: we included 79 patients (male: 64 /female 15). 69 had 46,XY and 10 had 46,XX karyotype. Diagnoses were as follow: CAH: n=10, AIS: n=9, gonadal dysgenesis: n=5 (partial: n=3 including 2 with residual Müllerian structures, complete: n=2), Anorectal malformation: n=2 (1 with residual Müllerian structures), 5alpha reductase deficiency: n=1, Denys-Drash syndrome: n=1, VACTERL: n=2, 46,XX DSD: n=1, 46,XY DSD: n=48 (including 5 with complex chromosomal rearrangement).
66 patients (83,6%) had an associated feature. Altogether, the five most associated features are as follow: facial morphology abnormalities (n=35), small for gestational age (n=30), orthopaedic abnormalities (n=23), nervous system morphology abnormalities (n=22) and cardiovascular system abnormalities (n=21). In the 46,XY subgroup, the most associated feature was facial morphology abnormalities (n=32). In the 46,XX subgroup it was adrenal glands morphology abnormalities (n=7).
Mean number of associated features per patient was 3,7 ± 3,2 [range:0-11].
Conclusions and perspectives: associated features are common in 46,XY and 46,XX DSD patients. This study emphasizes the need to investigate 46,XX and 46,XY DSD patients for associated features to allow early specific management of these patients and direct them toward novel genetic aetiologies
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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