102,144 research outputs found
Suicidal cut-throat and stab fatalities: Three case reports
No full textFatalities resulting from sharp force injuries may be of accidental, homicidal or suicidal origin. Cut-throat and cut-stab wounds are "effective" in homicidal attacks with sharp objects, e. g. knifes, while accidental injuries in this topographic region caused by sharp objects are rarely seen and most often caused by broken glass. Self-inflicted cut throat and stab wounds are uncommon but nevertheless a well recognized method of suicide. In these cases, presence or absence of particular features (e.g., hesitation marks, defensive wounds) can allow distinction between suicide and homicide, especially if further circumstances, i.e. atypical crime scene scenarios or missing suicide notes, need the forensic pathologist to have an incredulous approach regarding the manner of death. The present article describes three cases of suicidal cut throat and stab wounds - crime scene investigations as well as medical history and autopsy findings are discussed. © 2011 Romanian Society of Legal Medicine
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
The Practical Examination (Birth) as a simulation? Requirements for the simulation-based final examination in German midwifery education in connection with the amendment of the midwifery act
No full textBuschmann H, Peters T, Bauer N. The Practical Examination (Birth) as a simulation? Requirements for the simulation-based final examination in German midwifery education in connection with the amendment of the midwifery act. In: 21. Congress of the Nordic Federation of Midwives. Helsinki: NJF congress; 2022
Superficial vein thrombosis: differential diagnosis of circumscribed skin discolorations at autopsy
No full textMultidrug poisoning involving nicotine and tramadol
No full textA fatal case of multidrug poisoning by tramadol and nicotine is reported. Tramadol is a centrally acting analgesic used in the treatment of moderate to severe acute or chronic pain. Nicotine, a lipid-soluble alkaloid, is one of the most readily available drugs in modern society. A 46-year-old man was found dead in his bed, and a suicide note was discovered near the body. He had 25 transdermal nicotine patches attached to his thorax and abdomen. Two half emptied bottles were found on the bedside table; the toxicological examination revealed that they contained tobacco and nicotine as well as other drugs such as diphenhydramine. At autopsy, areas of fresh and old myocardial infarction as well as diffuse pulmonary congestion and edema were present. The tramadol concentration was 6.6 μg/mL in femoral venous blood, while levels of nicotine and its primary metabolite cotinine were determined to be 0.6 and 2.0 μg/mL in femoral venous blood. Based on these results, we determined the cause of death to be cardiorespiratory failure induced by the additive effects of tramadol and nicotine shortly after consumption. © 2009 Elsevier Ireland Ltd. All rights reserved
Thylakogaster namibiensis Brenke & Buschmann, 2009, sp. nov.
No full text<i>Thylakogaster namibiensis</i> sp. nov. (Figs. 1–5) <p> <i>Material:</i> 14 specimens of <i>Thylakogaster namibiensis</i> sp. nov. were found at four stations during the Diva 1 expedition (Tab. 1).</p> <p> <i>Holotype:</i> ♂, 1.9 mm, Area 4, Station #340 (EBS 09): 18°18.3’S 004°41.3’E to 18°19.4’S 004°41.9’E, 5395 m depth; ZMH K-40840 A–N, 14 slides. (Diva 1 Id No.: D1- HM9)</p> <p> <i>Paratype (Allotype):</i> 1 ♀, 1.6 mm, Area 4, Station #340 (EBS 09): 18°18.3’S 004°41.3’E to 18°19.4’S 004°41.9’E, 5395 m depth; ZMH K-40842. (D1- HM8)</p> <p> <i>Paratypes:</i> 1 ♂, 1.2mm, Area 5, Station #344 (EBS 10): 17° 06.2' S 004° 41.7' E to 17° 07.5' S 004° 42.3' E, 5415 m depth; ZMH K-40841 A–L, 12 slides. (D1- HM1). 1 juvenile (stage IV) 1.1mm (D1- HM3) and 1 juvenile (stage II) 0.7mm (D1- HM2) both from Area 6, Station #348 (EBS 11): 16° 18.1' S 005° 27.2' E to 16° 19.3' S 005° 27.2' E, 5387m depth; ZMH K-40843, K-40844.</p> <p> <i>Distribution</i>. Known only from the Angola Basin, Atlantic Ocean, 850 km west of Namibia. Depth range: 5387–5415 m.</p> <p> <i>Etymology.</i> Thylakogaster namibiensis sp. nov. is named after the sample locality: the new species was sampled 850 km westwards of the African coast off Namibia, in the Atlantic Ocean.</p> <p> <i>Diagnosis</i>. Cephalothorax-pereon length 3 times longer than wide. Antenna 1 of copulatory male consisting of 3 articles in peduncle and 12 in flagellum, aesthetascs present on articles 9–13 (formula: P3–F12[A8–12]). Article 3 length 1.1 article 2 length. Antenna 2 with 6 articles in peduncle and 11 in flagellum. Pleotelson length 0.66 cephalothorax-pereon length, length 1.34 width. Pleotelson with 30–40 simple spines developed on each lateral half. Uropods mace-like, broadened, inserting beneath broad keel close to rounded tip of pleotelson. Pleotelson nearly as long as broad, with rounded tip and small disto-medial projection, laterally expanded into 2 huge bumps on either side of frontal indentation.</p> <p> <i>Description of male (description of pereopods from juvenile paratypes):</i> Body (Fig. 1a–d) compact, cephalothorax-pereon length width 1.51, dorsoventrally flat and convex, unpigmented.</p> <p>Cephalothorax (Fig. 1a, b, e) rounded, length 0.27 cephalothorax-pereon length. Clearly visible fronsclypeal ridge developed anteriorly. Cephalon fused completely to first pereonite. Antennal insertion located on small projection on dorso-lateral surface.</p> <p>Pereon (Fig. 1a, b) with 1–2 spines on lateral margins of pereonites 1–7 next to coxae. Pereonites 1–3 of subequal proportions. Pereonite 3 widest. Pereonites 4–7 decreasing in length, with one or 2 small simple spines on ventral margins.</p> <p>Pleotelson (Fig. 1a, d, e, g) nearly as long as wide, length 0.66 cephalothorax-pereon length (measured basis of Plt to apex), with rounded tip; located dorsally above pereon and covering more than last 6 pereonites; laterally expanded into 2 huge bumps on either side of a frontal indentation. Pleotelson with 30–40 simple spines on each lateral side, often broken off at ends. Frontal indentation spineless. Uropods tiny, positioned on projecting lobes on ventral side close to pleotelson tip. Comb-like row of thin, unequally bifid setae below insertion of uropods (Fig. 1c)on both posterior margins (Fig. 1d). Setae more closely together than lateral cuticular spines on pleotelson. Both setae and spines increasing in length from tip to basis of pleotelson.</p> <p>Pleopods 1 and 2 in a posterio-dorsal position due to rounded form and position of pleotelson. Pleotelson covered entirely with spines in both sexes. External surfaces of male pleopods 1 and 2 equipped with single rows of spines. Surface of female operculum completely covered with strong spines.</p> <p>Antenna 1 (Fig. 2c, d): about as long as cephalothorax-pereon length, inserting dorso-medially at basis of A2. 3 articles in peduncle: article 1 with 1 broom seta and 1 short simple seta on disto-frontal margin (Fig. 2f). Article 2 with 1 plumose seta on disto-ventral margin. Article 3 without setae. Length ratio of peduncle articles: 1:0.7:0.8. Flagellum composed of 12 articles. Article 1 short, second article elongated, article 12 tiny (Fig. 2e). Length ratio of flagellar articles: 1:5.5:2:2.2:2:2.5:2.5:2.8:2:1.5:2.2:0.25. Flagellar articles with 1–2 fine simple seta. Flagellar articles 8–12 with 1 single aesthetasc each.</p> <p>Antenna 2 (Fig. 2b): length 2.0 cephalothorax-pereon length. Peduncle with 6 articles (Articles 1 broken off, article 2 damaged during dissection). Articles 1–4 short (only articles 2–4 are illustrated). Article 3 with 1 small seta on ventral side. Article 4 with 2 unequally bifid setae on dorsal side. Articles 5 and 6 elongated, bearing unequally bifid setae at irregular intervals (Articles 5 partially fractured in illustrated specimen). Setae insert with slight elevation, most setae broken off. Length ratio of peduncle articles: 1:1.1:0.5:1:8:14. Flagellum with 11 articles, first and second elongated, remaining articles smaller, subequal. Flagellar articles 1, 3 and 5 without setae, 8 with 1, articles 2, 4, 7, 9 and 10 with 2 setae. Article 6 with 3 small and thin simple setae. Article 11 with 5 long, thin setae on distal end (Fig. 2a).</p> <p>Mandibles (Fig. 2g, h): proximally broad, tapering distally, without palp. Left mandible with long, slender, simple, medial seta. Right mandible with 1 short, simple seta medially and 1 slender, simple spine and short, strong spine laterally.</p> <p> Left incisor process with 5 teeth with cuticular wrinkles, ventral-most tooth largest, remaining teeth decreasing in size to dorsal side. <i>Lacinia mobilis</i> of left mandible broad, bearing 4 prominent teeth and 1 small tooth. Setal row of 4 curved spines and 2 slender, simple setae. Molar process finger-like, with 7 long, slender, simple setae.</p> <p>Right incisor process with 5 broad teeth of approximately same size, with cuticular wrinkles. Setal row of 5 curved spines, each spine serrated with 7 strong, short teeth; between curved spines some long and slender simple setae. Molar process finger-like, distal with 12 long, slender, simple setae.</p> <p>Maxilla 1 (Fig. 3e, f): Outer lobe of left maxilla 1 terminally with 11 spine-like setae: 6 stout and rough serrated setae, 4 long setae serrated and equipped with a dense comb of fine setae and 1 simple, fine, ventral seta. Outer lobe of right maxilla 1 terminally with 11 spine-like setae of comparable size: 7 stout and rough serrated setae, 2 setae serrated and equipped with dense comb of fine setae and ventrally 2 simple fine setae. Inner lobe of right maxilla 1 with 3 long and slender setae.</p> <p>Maxilla 2 (Fig. 4a, b): middle and outer lobe subequal in length. Tips of middle and outer lobes with 3 long, single, side, plumose seta and 1 simple, media seta. Outer lobe also with 2 combs of 4 fine setae laterodistally. Inner lobe shorter and broader than middle and outer lobes. Inner lobe with 11 simple setae: 8 short on tip and 3 long on median margin. Proximal to these with 3 long and 7 small additional setae.</p> <p>Maxilliped (Fig. 3a–d): epipodite small and triangular, carrying numerous fine setae on its surface and lateral margins, reaching only half of length of lobe. Lateral margin of lobe irregularly rounded, tip truncated, with simple setae. Distal part of lateral margin of lobe with row of fine setae. Medial margin of lobe straight. Lobes connected by 5 (left lobe 3, right lobe 2) retinacula (Fig. 3b, d). Retinacula with 5 prominent teeth and cuticular wrinkles. Palpus long and slender, about twice as long as lobe. Palpus tapering distally, composed of 5 articles. All articles with numerous fine setae on surface and lateral margins. Length ratio of articles: 0.3:0.7:1:1.5:1.2. All articles with thin, long setae as follows: 1 with single seta, 2 with 2, 3 with 4, 4 with 3 and 5 with 7 long setae.</p> <p>Pereopods (Fig. 4c–f): all pereopods insert on elongated lateral projection (Fig. 1a, e)</p> <p>Pereopod 1 (Fig. 4d): robust, length 1.3 cephalothorax-pereon length, subchelate with prominent, strong, unequally bifid setae of altering length on basis, ischium, merus and carpus. Basis with 1 unequally bifid seta on ventral margin. Ischium length 0.5 basis length, with 3 unequally bifid setae and 2 simple setae on ventral and 2 unequally bifid setae on dorsal margin. Merus short, with 6 unequally bifid setae, 3 on ventral and 3 on dorso-frontal margin. Carpus elongated, longer than basis, with 11 strong unequally bifid on ventral margin opposite to propodus and dactylus and 5 additionally unequally bifid setae on proximal medial surface.</p> <p>Propodus with row of 5 fine setae on ventral and 2 simple setae on dorsal margin. Dactylus with 9 long simple setae (Fig. 4f).</p> <p>Pereopods 2–7 slender, sub-similar walking legs. Coxa of pereopods 2 to 7 recognizable but fused with pereonites and only slightly movable. All coxae with 3–5 strong, simple spines.</p> <p>Pereopod 2 (Fig. 4c): length 1.4 cephalothorax-pereon length. Basis with 3 slender simple setae on ventral margin (see remarks). Ischium as long as broad, with 5 unequally bifid setae, 1 on ventral and 4 on dorsal margin. Merus with 2 setae on ventral and 4 setae on dorsal margin. Carpus long, slender, with row of long unequally bifid setae and long simple setae on ventral margin opposite to propodus. 4 unequally bifid setae dorsally and additionally 1 broom seta distally. Propodus narrower, but as long as carpus. Propodus with more than 18 long, robust, unequally bifid setae. Terminally with 7 slender, simple setae. Dactylus with 7 long simple setae (Fig. 4e).</p> <p>Pleopods (Fig. 5a–e): male pleopods 1 and 2 forming posterio-ventral part of pleotelson, completely covering branchial cavity.</p> <p>Pleopod 1 (Fig. 5a): male pleopod 1, length 3.7 width, lateral margins nearly parallel, tapering in the distal fifth. Ventral surface with row of 4 strong spines each. Disto-lateral corners with 8 small, hair-like setae.</p> <p>Pleopod 2 (Fig. 5e): male pleopod 2, length 3.0 width,with 2 rows of 7 cuticular spines on external surface. Lateral margin with dense row of long, slender setae. Stylet (endopodite) short, robust, stylet length 0.33 protopod length. Exopodite forms a small lobe disto-medial of endopodite.</p> <p>Pleopod 2 (Fig. 1g): female pleopod 2 tapering distally, truncate proximally, completely covering branchial cavity. External surface with irregularly distributed cuticular spines.</p> <p>Pleopod 3 (Fig. 5b): exopodite elongated and hemispherical, 2-articulated, lateral and disto-medial margins with rows of numerous long, hair-like setae, distal article with 1 simple seta apically. Endopod length 1.4 width, distally rounded, with 3 strong, plumose, terminal setae and hair-like, medial and apical setae.</p> <p>Pleopod 4 (Fig. 5c): transparent, small, length 2.5 width, without setae, exopodite slender.</p> <p>Pleopod 5 (Fig. 5d): transparent, small, length 2.8 width ratio, without setae, exopodite reduced.</p> <p>Uropods (Fig. 1c, f): inserting beneath broad keel on ventral margin of branchial cavity close to tip of pleotelson, uniramous, cylindrical. Distal part swollen, rounded, with 5 hair-like setae.</p> <p> <i>Remarks.</i> The copulatory male described bares only the antenna 1 and the first pereopods. The rest of the long appendages were broken off at their basis. For description of the lost antenna and the pereopod 2, a comparably large paratype was used. Except for the individuals described here, the long and extremely fragile antenna 1, antenna 2 and pereopods 3 to 7 were broken off on all specimens of <i>T. namibiensis</i> sp. nov., or the specimens were significantly smaller. Male and female of <i>T. namibiensis</i> show no sexual dimorphism, besides the female may be expanded if oostegites are developed.</p> <p>The inner lobe of the left maxillula and the distal part of the merus of pereopod 2 were damaged during dissection. The cuticular wrinkles on the surface of pleopod 3 may be artefacts.</p>Published as part of <i>Brenke, Nils & Buschmann, Anika, 2009, Thylakogaster namibiensis sp. nov. (Isopoda: Asellota: Janiroidea), a new species of Haplomunnidae from the southeast Atlantic deep sea *, pp. 381-394 in Zootaxa 2096 (1)</i> on pages 384-390, DOI: 10.11646/zootaxa.2096.1.23, <a href="http://zenodo.org/record/5323453">http://zenodo.org/record/5323453</a>
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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