186,967 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    The Authors reply: Comment on: “Handgrip weakness, low fat‐free mass, and overall survival in non‐small cell lung cancer treated with curative‐intent radiotherapy” by Burtin et al.

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    The Authors reply: Comment on: "Handgrip weakness, low fat-free mass, and overall survival in non-small cell lung cancer treated with curative-intent radiotherapy" by Burtin et al. We want to thank Dr Shafieesabet and Dr Doehner for the critical appraisal 1 of our findings. 2 The normative values for handgrip strength based on UK Biobank data include the 5th, 10th, and 25th percentile. While the authors propose the 5th percentile as cutoff to define handgrip strength as abnormally low, they also emphasize that the clinical relevance and prognostic value of this cut-point needs to be established. We a priori defined weakness using the 10th percentile based on our previous research in COPD, showing that the 10th percentile was the best prognostic factor in these patients. 3 Further, we fully agree that cancer cachexia is an established prognostic marker in patients with non-small cell lung cancer. Not surprisingly, we find a strong association between body mass index (BMI) and fat-free mass index (FFMI) in our dataset (r = 0.76, p < 0.001). Therefore , we preferred not to combine them in one model due to multicollinearity. When we replace FFMI by BMI (as a continuous variable or a dichotomous variable identifying underweight patients defined as BMI < 18.5 kg/m 2) in our multivariate model in patients with good functional status (WHO performance status 0 or 1), handgrip weakness remains a significant prognostic factor while BMI does not. This might be due to the observation that only 39 of 794 patients were underweighted, of which 13 also presented with handgrip weakness. Therefore, our data lack power to firmly investigate the prognostic role of BMI. Unfortunately, we did not record weight loss in our database. Interestingly, when excluding all underweighted patients, our findings remain unchanged, which suggests that FFMI and handgrip weakness can provide additional prognostic information in patients with a BMI within normal ranges. A more heterogeneous sample including a higher proportion of patients with features of cachexia is needed to explore to what extent body weight, fat-free mass, and handgrip strength can provide complementary prognostic information.Burtin, C (corresponding author), Hasselt Univ, Fac Rehabil Sci, REVAL Rehabil Res, Agoralaan Gebouw A, Diepenbeek, Limburg, Belgium. [email protected]

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Effects of a community-based pulmonary rehabilitation programme during acute exacerbations of chronic obstructive pulmonary disease - a quasi-experimental pilot study

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    Background: Pulmonary rehabilitation (PR) is a cornerstone intervention for the management of patients with stable chronic obstructive pulmonary disease (COPD). However, its role during acute exacerbations (AECOPD) is controversial since most studies have been conducted in hospitalised patients, when more than 80% of AECOPD are managed on an outpatient basis. This quasi-experimental pilot study assessed the effects of a community-based PR programme during mild-to-moderate AECOPD. Methods: Outpatients were recruited from hospitals and allocated to experimental (EG) or control (CG) groups. EG received standard medication plus 3-weeks of PR. The CG received standard medication. Dyspnoea (mMRC), quadriceps muscle strength (QMS), functionality (5-repetition sit-to-stand test) and impact of the disease (COPD assessment test (CAT)) were assessed within 48 h of the AECOPD onset and after PR. Symptoms of dyspnoea and fatigue (mBorg), heart and respiratory (RR) rates and peripheral oxygen saturation (SpO2) were assessed at rest and monitored in all PR sessions. Need for hospitalisation was monitored during the 3-weeks. Results:Twelve patients (69 ± 7 years, FEV1 52 ± 27 pp) in the EG and eleven in the CG (66 ± 9 years, FEV1 55 ± 22 pp) were enrolled. The EG presented significant improvements on QMS (Pre 21.0 vs. Post 25.0, p = 0.012), CAT (Pre 23.0 vs. Post 14.5, p = 0.008), symptoms of dyspnoea at rest (Pre 3.0 vs. Post 1.0, p = 0.008), SpO2 (Pre 94.0 vs. Post 96.0, p = 0.031) and RR (Pre 24.0 vs. Post 20.5, p = 0.004). No significant improvements were found in the CG.publishe

    Withdrawn by Author

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    &lt;p&gt;Withdrawn by Author&nbsp;&lt;/p&gt

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Dr. Edward P. Wimberly, ITC, July 2011

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    This video is a conversation with Dr. Edward P. Wimberly. Dr. Wimberly talks about his book, "No Shame in Wesley's Gospel: A Twenty-First Century Pastoral Gospel". Brad Ost, AUC Woodruff Library, is the interviewer

    Author Rights and Scholarly Publishing

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    Originally posted at http://blog.library.gsu.edu/2014/10/24/author-rights-and-scholarly-publishing/</p

    Brown seaweed polyphenols as novel antioxidants for better health and food quality

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    In the Far East and Pacific, there is a long tradition of consuming seaweeds as sea vegetables, while in western countries the principal use of seaweeds is as source of phycocolloids (eg. thickening and gelling agents for agro-food industry). In Asia, recent epidemiological studies have demonstrated that regular consumption of seaweeds might be related to a reduction of prostate, colorectal and breast cancer risk. Researches carried out on natural products from seaweeds lead to the identification of a variety of antioxidant compounds, among which polyphenolic compounds. Brown seaweeds are particularly rich in polyphenols: from 5 to 15 % of the dry weight. These compounds are made from phloroglucinol units, connected by aryl/aryl bonds (fucols), by aryl ether bonds (phlorethols) or both (fucophlorethols). Some of them contain one additional hydroxyl group at each second ring and a regular sequence of para- and ortho- positioned ether links (fuhalols and pseudofuhalols). In comparison with terrestrial plants, little is known about the antioxidant activity of seaweed polyphenols. The main objectives of the SEAHEALTH project carried out with financial support from the Commission of the European Communities (“Quality of Life and Management of Living Resources” RTD programme) is to demonstrate benefits of seaweeds antioxidant substances on human health (prevention of atherosclerosis and cancer) and food quality. This paper presents the results obtained during the first half of the SEAHEALTH project. In a first step, extraction/purification process of seaweed antioxidants was optimised. For comparative reasons and to establish a superior method for polyhenols determination, two quantitative methods were evaluated: Folin Ciocalteu’s and DMBA (2,4-dimethoxybenzaldehyde). Qualitative analysis were performed by 1H NMR and HPLC-MS. Size exclusion chromatography (SEC) was evaluated as a method to separate polyhenols according to their molecular weight. An important antioxidant and scavenging activity of some of the extracts was observed in vitro (DPPH and ORAC tests). The capacity of seaweed extracts to scavenge superoxide anion radical generated during the oxidation of xanthine to uric acid in the presence of xanthine oxidase was measured. The influence of the extracts on carcinogen metabolism was assessed by measuring inhibition of phase I enzyme (cytochrome P450 Cp1A) activity. The anti-inflammatory and the anti-hormonal effects of the extracts were evaluated by measuring inhibition of cyclooxygenase and aromatase activity, respectively. Acute toxicological studies were performed on mice and rats by oral and intraperitoneal routes with two different oral doses of seaweed extracts. Finally, some food products (fruit juices and yoghourts) were formulated from seaweed extracts. Results showed that antioxidant activity was still detectable in formulated products
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