103,293 research outputs found
The M. I. T. linear accelerator as a pulsed neutron source for a time-of-flight neutron spectrometer
No full textThesis (B.S.) Massachusetts Institute of Technology. Dept. of Physics, 1951.Bibliography: leaf 27.by James Lee Burkhardt and John David Fox.Thesis (B.S.) Massachusetts Institute of Technology. Dept. of Physics, 1951
Potential to enhance the prescribing of generic drugs in patients with mental health problems in Austria; implications for the future
No full textScrutiny over pharmaceutical expenditure is increasing leading to multiple reforms. This includes Austria with measures to lower generic prices and enhance their utilization. However the situation for newer antidepressants and atypical antipsychotic medicines (AAPs) is different to PPIs, statins, and renin-angiotensin inhibitor drugs with greater tailoring of therapy and no wish to switch products in stable patients. Authorities welcome generics though given the high costs particularly of single-sourced AAPs. Assess (a) changes in utilization of venlafaxine versus other newer antidepressants before and after availability of generics, (b) utilization of generic versus originator venlafaxine, (c) price reductions of venlafaxine over time and their influence on total expenditure, (d) utilization of risperidone versus other AAPs, (e) suggest potential additional reforms that could be introduced if pertinent to further enhance the use of generics. A quasi-experimental study design with a segmented time series and an observational study. Utilization measured in defined daily doses (DDDs) and total expenditure per DDD and over time. No appreciable changes in the utilization of venlafaxine and risperidone after generics. The reduction in expenditure/DDD for venlafaxine decreased overall expenditure on newer antidepressants by 5% by the end of the study versus just before generics despite a 37% increase in utilization. Expenditure will further decrease if reduced prescribing of duloxetine. Depression, schizophrenia, and bipolar diseases are complex diseases. As a result, specific measures are needed to encourage the prescribing of generic risperidone and venlafaxine when multiple choices are appropriate. Authorities cannot rely on a "Hawthorne" effect between classes to enhance the use of generics. Measures may include prescribing restrictions for duloxetine. No specific measures planned for AAPs with more multiple-sourced AAPs becoming availabl
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Web-based registry for cytomegalovirus (CMV) infection and disease after pediatric renal transplantation
No full textWeb-based registry for cytomegalovirus (CMV) infection and disease after pediatric renal transplantation - Intermediate Analysis
No full textWeb-based registry for cytomegalovirus (CMV) infection and disease after pediatric renal transplantation
No full textWeb-based registry for cytomegalovirus (CMV) infection and disease after pediatric renal transplantation - Intermediate Analysis
No full textHandwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
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