169,888 research outputs found
Ice recrystallization inhibition and molecular recognition of ice faces by poly(vinyl alcohol)
No full textBudke C, Koop T. Ice recrystallization inhibition and molecular recognition of ice faces by poly(vinyl alcohol). ChemPhysChem. 2006;7(12):2601-2606.The effects of poly(vinyl alcohol) (PVA) on the Ostwald ripening of polycrystalline ice samples are studied. At -6 degrees C, ice recrystallization in sucrose solutions is inhibited at PVA concentrations down to 0.005 mg mL(-1), with a recrystollization inhibition constant of 48.9 mL mg(-1). Ice growth-habit experiments reveal molecular recognition of the arrangement of water molecules in the ice by PVA molecules, and indicate that PVA molecules adsorb to the primary and secondary prism faces of hexagonal ice, lh. Based on these observations, together with an analysis of the O-atom pattern in ice and the conformation of OH groups in PVA, an adsorption model is proposed. We suggest that PVA segments adsorb to the primary and secondary prism faces of ice parallel to the c axis with a linear misfit parameter of only 2.7%, most likely via multiple hydrogen bonds. The proposed adsorption mechanism is discussed in the light of recent thermal hysteresis and scanning tunneling microscopy experiments
Echinococcus multilocularis in North America: the big unknown
No full textOver the last decade, studies have begun to shed light on the distribution and genetic characterization of
Echinococcus multilocularis, the causative agent of alveolar echinococcosis (AE), in North America. Recent findings
indicate that the parasite is likely expanding its range in the central region of the United States and Canada and that
invasions of European strains might have occurred. In our review, we present the available data on E. multilocularis
infections in wild and domestic animals and humans in North America and emphasize the lack of knowledge on the
distribution of the parasite in wild and domestic hosts. Furthermore, we stress the need to better understand the complexity
of host communities and their roles in shaping the transmission and distribution of the parasite. We hypothesize
that a lack of knowledge about AE by North American physicians might result in the misdiagnosis of cases and
an underestimation of disease incidence. The endemic presence of the parasite in urban areas and a recent human case
in Alberta, Canada, suggest that the scientific community may need to reconsider the local public health risks,
re-assess past cases that might have been overlooked and increase surveillance efforts to identify new cases of human
AE
Antifreeze glycopeptide analogs: synthesis, structural, and functional analysis
No full textPlattner C, Nagel L, Budke C, Koop T, Sewald N. Antifreeze glycopeptide analogs: synthesis, structural, and functional analysis. AMINO ACIDS. 2009;37:41-41
Supplementary Data to the scientific article: "Boreal pollen contain ice-nucleating as well as ice-binding ‘antifreeze’ polysaccharides", published in Scientific Reports 7, 41890 (2017)
No full textDreischmeier K, Budke C, Wiehemeier L, Kottke T, Koop T. Supplementary Data to the scientific article: "Boreal pollen contain ice-nucleating as well as ice-binding ‘antifreeze’ polysaccharides", published in Scientific Reports 7, 41890 (2017). Bielefeld University; 2017.The files in this directory contain the source data of all x-y-plots shown in the figures of the scientific article given below. If you use any of these data in your scientific work or in the resulting publications please cite the corresponding original publication:
Boreal pollen contain ice-nucleating as well as ice-binding ‘antifreeze’ polysaccharides
by K. Dreischmeier, C. Budke, L. Wiehemeier, T. Kottke, and T. Koop, Scientific Reports 7, 41890 (2017);
doi: [10.1038/srep41890](http://dx.doi.org/10.1038/srep41890
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
A Multi-Language Comparison of Influences on Author Verification using Character N-Grams
No full textWe create a new multi-language corpus for author verification based on Wikipedia talkpages, and evaluate the influence that differences in topic and time have on character n-gram author profiles. Topic alignment between two texts is found to increase author verification precision, and an authors writing style is found to change over time, but not more significantly after 3 years than after 1 year.Information ArchitectureWISElectrical Engineering, Mathematics and Computer Scienc
A 0.12mm<sup>2</sup> Wien-Bridge Temperature Sensor with 0.1°C (3σ) Inaccuracy from -40°C to 180°C
No full text Resistor-based temperature sensors can achieve much higher resolution and energy efficiency than conventional BJT-based sensors [1], but they typically occupy more area (> 0.25 mm 2 ) and have lower operating temperatures (le 125 {circ} {C}) [2]-[4]. This work describes a 0.12mm 2 resistor-based sensor that uses a Wien-bridge (WB) filter to achieve 0.1 {circ} {C} (3 sigma) inaccuracy from - 40 {circ} {C} to 180 {circ} {C}. Compared to a state-of-the-art WB sensor [4], it occupies 6 × less area and achieves comparable relative accuracy over a 76% wider operating range. Session 10.3 Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic InstrumentationMicroelectronic
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