1,721,047 research outputs found

    Jérôme Pozzi (dir.), De l’attachée de presse au conseiller en communication. Pour une histoire des spin doctors

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    Cet ouvrage dirigé par Jérôme Pozzi est issu d’une journée d’études organisée au Centre de recherche universitaire lorrain d’histoire (CRUHL), à l’université de Lorraine, le 12 mai 2016. Comme le précise dans l’introduction le directeur du volume, l’objectif de ce colloque n’était « pas de remettre en cause le travail des communicants, encore moins de juger leur action au prisme d’une quelconque échelle de valeurs, mais plutôt d’essayer d’éclairer les modalités de leur action » (p. 11). En dé..

    Mechanical circulatory support for acute heart failure in 2013: an update on available devices, indications and results

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    Severe acute heart failure often requires some form of mechanical support to circulation. The use of intraaortic balloon counterpulsation in postinfarction cardiogenic shock -perhaps the most common scenario of this kind- has been recently questioned in the IABP SHOCK trial. In the most severe forms, extracorporeal membrane oxygenation is becoming the mainstay of treatment to support circulation or in order to gain time for a further evaluation. Moreover, advances in technology and a reducing number of donors are leading to more extended indications to the implantation of ventricular assist devices. Herein, we offer a focused review on recent articles dealing with mechanical support to circulation in acute heart failure, which we found relevant in terms of their possible impact on therapeutic strategies and indicatio

    Surgical myocardial revascularization in patients with reduced systolic left ventricular function

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    Surgical myocardial revascularization in patients with reduced left ventricular function has been a matter of debate for decades. Recently published 10-years extension follow-up of the STICH trial have conclusively demonstrated benefit of surgical myocardial revascularization in patients with significant coronary artery disease and low left ventricular ejection fraction. However, selection of patients for surgery remains challenging as well as decision to perform percutaneous rather than surgical revascularization in this class of patients. New evidence helped to clarify the role of preoperative patients' characteristics as risk factors for surgery and to identify those patients who may benefit the most from surgery. Focus of this review is to review epidemiology, aetiology and pathophysiology of coronary artery disease in patients with reduced left ventricular function, role of viability and results of observational and investigational studies on revascularization in patients with reduced left ventricular function with a particular emphasis on relative indication of coronary artery bypass grafting and percutaneous coronary intervention and the surgical implications of development of ischemic mitral regurgitation or ischemic left ventricular aneurysm

    Repair of Posterior Infarct Ventricular Septal Defect in a Patient with Dextrocardia and Situs Inversus

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    We report a patient with situs inversus who developed a large posterior interventricular septum pseudoaneurysm with a septal defect following a myocardial infarction. The ventricular septum was approached through the left ventricle and the entrance of the pseudoaneurysm was repaired with a strip of equine pericardium

    A Simple Device for Morphofunctional Evaluation During Aortic Valve-Sparing Surgery

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    Valve-sparing operations for the treatment of aortic root disease with a structurally normal aortic valve are increasingly performed as they avoid prosthesis-related complications. Short- and long-term results are critically dependent on perfect intraoperative restoration of valve anatomy and function. Residual aortic regurgitation is the main cause of early failure, and it is the most common motive for reoperation. However, intraoperative morphofunctional valve assessment requires expertise, and only transesophageal echocardiography can provide reliable information. We describe a simple, economic, reproducible hydrostatic test to intraoperatively evaluate valve competency under direct visualization

    Implantable ventricular assistance systems (VAD) as a bridge to transplant or as 'destination therapy'

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    Heart failure is a complex clinical syndrome associated with a high mortality and morbidity rate. Despite the extensive pharmacological armamentarium, a non-negligible percentage of patients develop advanced heart failure and require further therapies. In these circumstances, heart transplantation remains the treatment of choice, but the limited number of donors and the reduction of potential candidates have made necessary to develop new technologies. Since the 1980s, left ventricular assist devices (LVADs) have been introduced and have completely revolutionized the landscape of advanced heart failure treatments. This article has identified the categories of patients who can benefit from the implantation of an LVAD and summarized the new classifications. In addition, the main LVADs are described, analysing the results of the main clinical studies, with particular reference to adverse events. Although there is no perfect LVAD, a multidisciplinary team approach, dedicated to the treatment of advanced heart failure, can guide the choices on the best device to implant, in order to minimize complications and improve the patient's quality of life
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