1,721,193 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Functional analysis of soluble guanylate cyclase isoforms using mouse transgenics : cardiovascular effects of targeted mutagenesis of the alpha 1 subunit
No full textDiss. doct. wetenschappen: biotechnologi
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Transcriptome analysis of monocytes and macrophages in mycobacterial infection and chronic kidney disease
No full textTissue macrophages and their circulating counterpart, the monocytes, constitute a key component of the innate immune system. Different triggers evoke different macrophage responses leading to different states of macrophage activation. The activation states of the following in vivo elicited macrophages were characterized by transcriptome profiling: (i) granuloma macrophages from mice after infection with Mycobacterium bovis BCG, and (ii) monocytes from patients with chronic kidney disease. Granuloma macrophages constitute an important component of granulomas, which are cellular aggregates of T cells and activated macrophages, and which are hallmarks of tuberculosis. By genome-wide expression profiling, we identified a specific molecular marker SynCAM1 for Th1 cytokine-related granuloma macrophages within the mononuclear phagocyte family. Moreover, we identified the differential regulation in granuloma macrophages of genes not previously associated with the in vivo macrophage response during mycobacterial infection. These included several chemotaxis-related genes and adhesion molecules. The regulation of SynCAM1 and some of the other newly identified molecules was dependent on TNF-derived signals, indicating that TNF might contribute to granuloma formation and/or maintenance not only by regulating expression of chemokines, but also expression of adhesion molecules in the granuloma. Thus, we identified several valuable targets for future research that might improve our understanding of the involvement of macrophages and of TNF in the granulomatous response during mycobacterial infection. Another part of the study was dedicated to the evaluation of monocytes from patients with chronic kidney disease (CKD). Monocytes in CKD are dysfunctional, and their particular activation state is believed to contribute to the major complications observed in CKD: (i) the slight pro-inflammatory activation state might contribute to accelerated atherosclerosis in CKD, and (ii) the blunted immune response upon further stimulation might contribute to increased susceptibility to infections. The transcriptome of monocyte/macrophage-related genes was analyzed in monocytes from CKD patients and controls, however, hardly any differences in gene expression were observed in the different study populations. Our results, together with previously described observations, indicate that it is only the CD16+ monocyte subset that is affected in CKD, and that post-transcriptional processes might be involved in the dysfunctional activation state
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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