2,638 research outputs found
Prevalence of referable, sight-threatening retinopathy in type 1 diabetes and its relationship to diabetes duration and systemic risk factors
No full textPurpose: The purpose of the study was to provide contemporary estimates for diabetic retinopathy (DR) prevalence in a well-defined UK cohort of patients with type 1 diabetes (T1DM) and investigate potential risk factors for proliferative diabetic retinopathy (PDR) and diabetic maculopathy.Patients and Methods: Four hundred and sixty four T1DM patients in North Hampshire had T1DM duration, demographic and systemic risk factor data evaluated retrospectively alongside their DR status in 2010 using logistic regression analysis.Results: Overall prevalence of any retinopathy, PDR, and maculopathy was 71.5%, 6.5%, and 10.8%, respectively. PDR and maculopathy prevalence were 0 and 0.7% for <10 years T1DM duration. PDR prevalence was 4%, 8%, and 16% for 10–19.9 years, 20–29.9, years and ≥30 years duration, respectively. Maculopathy prevalence was 15.6%, 18%, and 11% for 10–19.9 years, 20–29.9 years, and ≥30 years duration, respectively. In univariate analysis, PDR was associated with T1DM duration (odds ratio (OR) 1.07/year), age (OR 1.03/year), systolic blood pressure (OR 1.03/mmHg), and antihypertensive therapy (OR 10.63), while maculopathy was associated with duration (OR 1.03/year) and statin therapy (OR 2.83). In multivariate analysis, disease duration (OR 1.07/year) and antihypertensive therapy (OR 6.87) remained significantly associated with PDR, and maculopathy with statin therapy (OR 2.27).Conclusion:This study confirms T1DM duration is a strong risk factor for sight-threatening DR. Maculopathy and PDR prevalence within 10 years of T1DM diagnosis is very low. PDR prevalence at 10–20 years was 4% and then doubled for every 10-year interval thereafter up to 16% with ≥30 years duration. Antihypertensive therapy and statin therapy were strongly associated with PDR and maculopathy, respectively.</p
STRUCTURE OF THE ART-SPACE IN THE STORY "I" BY A.P. POTEMKIN
No full textThe author performs the analysis of the art space structure in A.P. Potemkin's story "I". Several interrelated spatial models are allocated and described: household space, natural space, social space, psychological space, transpersonal space
Pressure drop and turbulence statistics in transpired pipe flow
No full textMeasurements of turbulent flow in a horizontal pipe subjected to wall transpiration are presented. Results include data on global flow rates and pressure drop, and local mean and fluctuating velocity profiles. Two distinct flow transpiration rates are studied, = / = 0.0005 and 0.001. The effects of flow transpiration on the friction-coefficient are compared with theoretical predictions. The theory furnishes predictions accurate to 3\%
Fully Turbulent Mean Velocity Profile for Purely Viscous non-Newtonian Fluids
No full textThe characteristic near wall behavior of turbulent flow of purely-viscous non-Newtonian fluids is discussed for both power-law (P.-L.) and Herschel-Bulkley (H.-B.) rheological models. A proper scaling is presented for H.-B. fluids to establish an analogy with power-law fluids with same flow index. To provide reference data for turbulent flow of non-Newtonian fluids, DNS simulations of power-law fluids are conducted in a rectangular channel for a large range of power-law indices ( = 0.5, 0.69, 0.75, 0.9, 1, 1.2). The DNS data show that the mean velocity profile in the viscous and logarithmic layers follow expressions of the form and respectively, where shows a logarithmic dependency on the flow index.Comparison with some experimental data shows the above formulation to be valid for Reynolds numbers (based on shear velocity) as high as 1000
Author Correction: New perspectives on Neanderthal dispersal and turnover from Stajnia Cave (Poland)
No full textThe Author contributions section now reads:“W.N., A.N. and S.T. designed research; A.P., M.H., W.N., S.B., M.U., A.M., H.F., M.D.B., P.S., K.S., M.Ż., A.W., A.N. and S.T. performed research; A.P., M.H., W.N., S.B., M.U., A.M., H.F., M.D.B., P.S., K.S., M.Ż., A.W., A.N. and S.T. analysed data; A.P., M.H., S.T., W.N. and S.B. wrote the paper with the collaboration of all the co-authors.
Author Correction:A 41,500 year-old decorated ivory pendant from Stajnia Cave (Poland)
No full textCorrection to: Scientific Reports https://doi.org/10.1038/s41598-021-01221-6, published online 25 November 2021The original version of this Article contained errors in the author list where Marjolein D. Bosch was omitted from the author list, and Mikołaj Urbanowski was incorrectly listed as an author of the original Article, and has subsequently been removed.The Author contributions section now reads:“S.T. W.N. and A.N. conceived the project; S.T., W.N., A.P., M.B., S.C., M.D., H.F., A.M., M.D. B., D.P., M.P.R., C.M.R., V.S-M., G.M.S., P.S., M.S., K.S., A.V., F.W., H.W., A.W., M.Z., S.B., A.N., J-J. H., performed research; S.T., A.P., W.N., M.B., M.D.B., S.C., M.D., H.F., A.M., D.P., M.P.R., C.M.R., V.S-M., G.M.S., P.S., M.S., K.S., A.V., F.W., H.W., A.W., M.Z., S.B., A.N., J-J. H. analysed all archaeological data; S.T. and A.P. wrote the paper with the collaboration of all the co-authors.”The original Article and its accompanying Supplementary Information file have been corrected
Material Culture of the Volga Bolgars in the Scientific Works by A.P. Smirnov
No full textThe article considers the study of the scientific heritage of the outstanding Soviet archaeologist Aleksei Petrovich Smirnov, the founder of the scientific direction in the archaeology of the Volga-Kama region – Bulgaristics. Of particular interest are the scientific works of the researcher, which have become classic: "The Volga Bolgars" and "Essays on the ancient and medieval history of the peoples in the Middle Volga and the Kama regions" published in 1951 and 1952 respectively. In the first book, the author gives a detailed description not only of the social, economic and political events in the history of Volga Bolgaria within the formation approach, but also of the material culture of its population. The peculiarity of this part of A.P. Smirnov's research is that there is no typological classification here, although A.P. Smirnov uses its basic principles very often. The author claims that this was the result of the "Marxisation" of archaeological science carried out in the USSR in the 1930s, when the typological method was considered bourgeois and unsuitable for the Soviet history of material culture, as archaeology came to be called. A.P. Smirnov, well-versed in the typological method developed by his teacher V.A. Gorodtsov, deliberately limited its use. At the same time, he successfully applied the results of studies in the 1920s by his colleagues-archaeologists – A.V. Artsikhovsky, S.V. Kiselyov, V.V. Golmsten, and others, concerning the general analysis of the subject world in the context of social history. Smirnov, in the book "The Volga Bolgars", laid the foundations for further scientific developments of his students in the field of Bulgaristics, for example, T.A. Khlebnikova. These approaches were presented in A.P. Smirnov’s second work
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