170,240 research outputs found

    Breathing Space

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    The site-specific installation, Breathing Space, was the inaugural commission for York Museums Trust‘s new visual arts space at York St Mary‘s in 2005, and was funded by the Arts Council of England, York Museums Trust and Middlesex University. It is an example of Broadhead's recent work that develops new ways of encountering artwork in non gallery spaces (The Waiting Game, Upnor Castle, 1997; Drift, 2002, Pitshanger Manor, London). Explorative practice-based research investigated ways of creating a powerful, secular work that communicated to a wide range of ages, backgrounds and beliefs. All the elements of architecture which contribute to atmosphere were considered. Building upon and distilling this information and following a tight conceptual framework, the piece explored containment and separation, oppression and uplift; accessibility and inaccessibility, different viewpoints and a sense of stillness. Broadhead collaborated with sound artist Graeme Miller (Centre for Research into Creation in the Performing Arts, MU). A publication was produced to record and contextualise the piece, with an essay by Lynne Green and photographs by Jerry Hardman Jones. A strong education programme was organised, with various workshops and other events. The exhibition recorded 24,500 visitors. Comments in the visitor's books verified the intentions of the installation. A public talk by Broadhead and discussion on the Breathing Space project was held at the York Art Gallery. Alongside, Broadhead exhibited work in newly refurbished York Art Gallery (Tunnel Dress, 1999), and the Castle Museum (jewellery 1970s, 1980s) allowing a retrospective view of her career in three different venues across the city. Preview: Selvedge magazine, Dec 05, p7 Guardian Guide preview, 28.05.05, p37, Robert Clark http://www.bbc.co.uk/northyorkshire/content/articles/2005/09/16/breathing_space_feature.shtml http://www.bbc.co.uk/northyorkshire/culture/exhibition/2005/breathing_space/index.shtml http://www.yorkstmarys.org.uk/Page/ViewInstallation.aspx?CollectionId=

    Small car driver inflatable restraint system evaluation /

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    "Contract no. DOT HS-6-01412.""July 1978.""Minicars, Inc.""Final report."Cover title.Bibliography: v. III, p. R-1 ; v. IV, p. R-1.v. I. Executive summary / C. Strother -- v. II. Driver air cushion restraint (ACRS) development for 1976 Vega, Valiant, and Chevette subcompact vehicles / W. Broadhead, C. Strother -- v. III. Investigation of potential crash survivability of a current production subcompact vehicle equipped with an advanced driver restraint system / W. Broadhead, C. Strother -- v. IV. Evolving a low mount passenger air cushion restraint system (ACRS) for the Vega subcompact vehicle / C. Strother, T. Zinke.Mode of access: Internet

    Investigating novel therapies for osteosarcoma using advanced medical imaging

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    © 2012 Dr. Matthew L. BroadheadPublications included in thesis:Dowsey, M. M., Broadhead, M. L., Stoney, J. D. & Choong, P. F. (2009). Outcomes of total knee arthroplasty in English-versus non-English-speaking patients. Journal of Orthopaedic Surgery, 17(3), 305–309.Broadhead, M. L., Dass, C. R. & Choong, P. F. M. (2011). Systemically administered PEDF against primary and secondary tumours in a clinically relevant osteosarcoma model. British Journal of Cancer, 105(10), 1503–1511. DOI: 10.1038/bjc.2011.410Broadhead, M. L., Choong, P. F. M. & Dass, C. R. (2012). Efficacy of continuously administered PEDF-derived synthetic peptides against osteosarcoma growth and metastasis. Journal of Biomedicine and Biotechnology, 2012. DOI: 10.1155/2012/230298Broadhead, M. L., Dass, C. R. & Choong, P. F. M. (2009). Cancer cell apoptotic pathways mediated by PEDF: prospects for therapy. Trends in Molecular Medicine, 15(10), 461–467. DOI: 10.1016/j.molmed.2009.08.003Broadhead, M. L., Dass, C. R. & Choong, P. F. M. (2009). In vitro and in vivo biological activity of PEDF against a range of tumours. Expert Opinion on Therapeutic Targets, 13(12), 1429–1438. DOI: 10.1517/14728220903307475Broadhead, M. L., Clark, J. C. M., Choong, P. F. M. & Dass, C. R. (2010). Making gene therapy for osteosarcoma a reality. Expert Review of Anticancer Therapy, 10(4), 477–480. DOI: 10.1586/ERA.10.18Broadhead, M. L., Akiyama, T., Choong, P. F. M. & Dass, C. R. (2010). The pathophysiological role of PEDF in bone diseases. Current Molecular Medicine, 10(3), 296–301.Broadhead, M. L., Becerra, S. P., Choong, P. F. M. & Dass, C. R. (2010). The applied biochemistry of PEDF and implications for tissue homeostasis. Growth Factors, 28(4), 280–285. DOI: 10.3109/08977191003604513Broadhead, M. L., Clark, J. C. M., Dass, C. R. & Choong, P. F. M. (2010). Microarray: an instrument for cancer surgeons of the future? ANZ Journal of Surgery, 80(7-8), 531–536. DOI: 10.1111/j.1445-2197.2010.05379.xBroadhead, M. L., Clark, J. C. M., Myers, D. E., Dass, C. R. & Choong, P. F. M. (2011). The molecular pathogenesis of osteosarcoma: a review. Sarcoma, 2011. DOI: 10.1155/2011/959248Broadhead, M. L., Clark, J. C. M., Dass, C. R., Choong, P. F. M. & Myers, D. E. (2011). Therapeutic targeting of osteoclast function and pathways. Expert Opinion on Therapeutic Targets, 15(2), 169–181. DOI: 10.1517/14728222.2011.546351Babazadeh, S., Broadhead, M. L., Slavin, J. L. & Choong, P. F. M. (2009). An interesting diagnosis for a presacral mass: case report. International Seminars in Surgical Oncology, 6(18). DOI: 10.1186/1477-7800-6-18Babazadeh, S., Broadhead, M. L., Slavin, J. L., Schlicht, S. M. & Choong, P. F. M. (2010). Giant cell tumour of metacarpal diaphysis. European Journal of Radiology Extra, 75(1), e31–e36. DOI: 10.1016/j.ejrex.2010.04.008Broadhead, M. L., Babazadeh, S., O'Brien, B. & Choong, P. F. M. (2010). Thigh enlargement and the art of misdirection. ANZ Journal of Surgery, 80(11), 839–840. DOI: 10.1111/j.1445-2197.2010.05503.xBroadhead, M. L., Babazadeh, S., Goldwasser, M. & Choong, P. F. M. (2011). Waxing and waning of joint motion. Grand Rounds, 11, 44–47. DOI: 10.1102/1470-5206.2011.0011Babazadeh, S., Broadhead, M. L. & Choong, P. F. M. (2011). If you are called to lead, you are called to serve. ANZ Journal of Surgery, 81(6), 401–403. DOI: 10.1111/j.1445-2197.2011.05782.xBroadhead, M. L., Babazadeh, S., Ng, K. W., Choong, P. F. M. & Stoney, J. D. (2011). Atraumatic bilateral femoral neck fractures during pregnancy: a missed diagnosis. Australian and New Zealand Journal of Obstetrics and Gynaecology, 51(6), 563-564. DOI: 10.1111/j.1479-828X.2011.01366.xBabazadeh, S., Broadhead, M. L., Schlicht, S. M., Powell, G. J. & Tymms, G. M. (2011). Pathologic fracture of a calcaneal aneurysmal bone cyst. The Journal of Foot and Ankle Surgery, 50(6), 727–732. DOI: 10.1053/j.jfas.2011.04.036Osteosarcoma is the most common primary cancer of bone. Current best treatment consists of chemotherapy and surgery, however many tumours are chemoresistant. Spread of osteosarcoma to the lungs is frequent and is the most common cause of death. This thesis examines the role of pigment epithelium-derived factor (PEDF) in the processes of osteosarcoma growth, invasion and metastasis. In order to evaluate this potential role, both in vitro and in vivo studies have been performed. In vitro studies have examined the biological effects and mechanisms of PEDF. PEDF exhibits a multifaceted ability to inhibit osteosarcoma tumorigenicity. PEDF inhibits proliferation, induces apoptosis and reduces cell cycling of osteosarcoma cells in vitro. Additionally, the metastatic capacity of osteosarcoma cell lines is diminished by PEDF. Osteosarcoma cells treated with PEDF demonstrate an enhanced capacity for adhesion and a reduced ability for invasion through collagen I, the most abundant protein in bone. An established murine model of orthotopic osteosarcoma has been optimised for the evaluation of novel therapeutic agents in vivo. This model allowed for an evaluation of systemically delivered PEDF and PEDF-derived peptides, both as sole treatments and in combination with doxorubicin. Systemic administration of PEDF causes a reduction in both primary tumour volume and pulmonary metastatic disease. PEDF-derived peptides, StVOrth-2 (residues 78-102) and StVOrth-3 (residues 90-114) were also delivered systemically. StVOrth-2 primarily restricts growth of primary osteosarcoma while StVOrth-3 restricts pulmonary metastatic disease. Finally, advanced medical imaging techniques have been applied to this murine model of orthotopic osteosarcoma for the study of tumour growth, invasion and metastasis; in vivo bioluminescent imaging, [18F]-Fluoride-PET, [18F]-FDG-PET and micro-computed tomography provide novel information about this model. Use of these imaging modalities has improved osteosarcoma modelling and allowed closer monitoring of disease progression. This is the first time that in vivo imaging has been used in the assessment of PEDF’s anti-osteosarcoma properties and is a major advance from previously published studies demonstrating direct effects on osteosarcoma growth and metastasis

    New Work: Exchange of Views; Over to You I, II, III; Sound of Breaking Glass.

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    Following on from previous exhibitions at Barrett Marsden Gallery (Chiaroscuro, 2000; Court, 2002), this body of work explored continuing concerns with the boundaries between self and non self, public and private spaces and ways objects can engage and invite interaction. The work used the language of materials and processes and the aesthetic of simple, distilled images with strong visual impact. Three major, new works used commonplace elements: window, net curtain and shadow, that signify a sense of territory. These explored the act of looking and the perspective of the viewer. Exchange of Views was an image of an outsized net curtain, made of hundreds of mirrored fragments, which offered oscillating views of both curtain image and reflected images, and acted as a divide into real and unreal, accessible and inaccessible space. Another work, Sound of Breaking Glass, comprised unique images printed from inked window glass and each journey through the press caused the glass to break further; they track disintegration and fragmentation through material and process. These were made during a residency at Pilchuck Glass School (May 2006). Pilchuck invites accomplished visual artists in all media to contribute to the artistic richness of the centre. Dr Tessa Adams's essay accompanied the exhibition (downloadable). Her special interest is the way in which psychoanalytic assumptions frame creative experience. She is Visiting Fellow, Goldsmiths College, and Art Theorist and Psychoanalytic Psychotherapist, co-editor of The Feminine Case: Jung, Aesthetics and Creative Process, published by Karnac. http://www.bmgallery.co.uk/broadhead/cb_exhibit06/cb_exhibit06.htm Review: Selvedge magazine, Dr Jessica Hemmings, issue 15. The works toured to subsequent venues: Glynn Vivian Art Gallery and Museum, Swansea, 8/02-1/42007 http://www.artfacts.net/index.php/pageType/instInfo/inst/8995 http://www.waterfrontonline.co.uk/articles/2007/01/29/preview-the-glynn-vivan-art-gallery SOFT, Norwegian Textile Artists, Oslo, Norway, 25/08-7/10/2007 (British Council funded). http://www.tekstilkunst.org/soft/exh-broadhead-en.php http://underskog.no/kalender/22719/forestilling/28421 http://www.listen.no/update/k-search1.tpl?do=wo&ord=bw&findfirst=Broadhea

    The Dress.

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    The Space Between was an international conference on the location of textile practice between art, fashion, craft, design and science. The themes included the impact of new technologies, globalisation and the breakdown of boundaries of traditional practice. Three international subject experts refereed each paper. Academics, practitioners and researchers from Canada, Brazil, Turkey, Great Britain and Australia contributed to the three-day conference, where 68 presentations were given. The event was supported by Australian Council for the Arts; Government of Western Australia; Arts WA and Curtin University of Technology Humanities Cultural Projects Committee. The proceedings were published on a web site http://www.thespacebetween.org.au and also on CD. Broadhead's paper, The Dress, identified and analysed why the dress has become widely adopted as a means of expression and site for exploration in contemporary practice, and how it has been used by artists and designers as symbol, presence and performance element since the 1960s. The paper drew on knowledge gained through Broadhead's practice and accumulated over the previous 10 years. Broadhead's work using the dress has been recognised as a consistent and significant contributor to this subject area by: the Jerwood Prize for Applied Arts: Textiles (1997) http://www.craftscouncil.org.uk/Exhib/jerwood/index.htm; Narrative Threads: A Series of Interviews with Major Textile Artists, NEVAC/Goldsmiths College, Constance Howard Resource Centre, London, 2002 http://www.media.uwe.ac.uk/nevac/video.htm; Artfund purchase Ulster Museum Double Dresses (2006) http://www.artfund.org/search/artist/9227/caroline-broadhead; and her work being exemplified for coursework for GCSE http://www.bbc.co.uk/schools/gcsebitesize/art/gallery2/caroline_broadheadrev2.shtml Broadhead was also invited to participate in the exhibition of international textile artists in the Curtin Art Gallery as one of the major supporting events, CD catalogue. She was one of three exhibitors who gave a public talk in the gallery. She was also invited as Artist in Residence for 5 weeks. http://info.art.curtin.edu.au/previous_artists.cf

    Who Cares

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    Who Cares is a cross-disciplinary dance video project (dance and visual arts) that explores and applies the use of thermal imaging in creating an innovative new work which, in partnership with NHS staff, reflects on the role of touch as a signifier of care, contamination,intimacy and trust. The format of presentation can either be in miniature on a series of ipods within a gallery space, or large-scale projection within or outside spaces, dependent on the needs of the venue or Festival. Collaborating artist Caroline Broadhead. Dancers: Alice Labant and Martina Conti

    Who Cares installation at IFTR 2025

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    Who Cares is a video installation work created by choreographer Angela Woodhouse and visual artist Caroline Broadhead using dance and thermal imagery that draws on the expanded body through heat data to explore themes of touch, heat trace, intimacy, and care. Dancers Martina Conti and Alice Labant. The piece is made up of 7 videos between 3-5 minutes in length. You are free to view for as long as you wish. Videos in order individually titled: Distancing  Mingle  Stir Cover up In Isolation Shift  Trac

    Between

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    The dancer approaches and embeds herself within her audience her arm covered loosely with gold leaf seemingly diseasing the skin. She claims attention. The gold is displaced, passed on, pressed into the skin – a kind of burn. Meanwhile, in the distance another performer is preoccupied in her private space, absorbed in subtle gestures in preparation for what is to come… Angela Woodhouse and Jerwood award winning artist Caroline Broadhead bring you a stunning performance installation, Between. Setting visual spectacle against intimate exchanges, the artists interrogate what it is to experience dance performance. This unique work is made in collaboration with exceptional performers Stine Nilsen (Candoco Dance Co)
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