14 research outputs found
Pattern of Drug Information Queries in a South Indian Tertiary Care Teaching Hospital
No full textDrug information centers have been established to provide unbiased information to healthcare workers and patients. The pattern of drug information queries received and answered by the drug information centre in a tertiary care teaching hospital in South India was assessed. Prospectively documented drug information queries, received and answered by the drug information centre over a 15-month period, were reviewed retrospectively for various parameters including status of the requestor, mode of receipt, mode of reply, type of query, purpose of query and references used. A total of 2010 queries were received and answered during the study period. Queries were received mainly from physicians (41 %), followed by nurses (n=595; 30 %) and pharmacists (n=462; 23 %). Dentists, students and healthcare professionals from outside the institution accounted for 139 (6 %) queries. Internet-based resource was the main reference source (n=952; 47 %) followed by textbooks, intranet resources and journals. Patient care-related queries were the most common. The information sought included product identification (22 %), drug dose or schedule (16 %), product availability (13 %), drug of choice/therapeutic alternatives/therapeutic use (10 %), product information (10 %), drug use in special populations and administration (6 % each), compatibility/stability/storage (5 %) and adverse reactions (4 %). The drug information center in a teaching hospital handles a wide range of queries from various healthcare workers, meets specific healthcare needs and serves as a valuable source of drug information. The impact of this service on improving patient care and minimizing errors warrants further study
Commentary on: “Chronic Use of Hydrochlorothiazide and Risk of Skin Cancer in Caucasian Adults: A PharmLines Initiative Inception Cohort Study
No full textAbstract is missing (Correspondence
Electronic Prescribing System in a Teaching Hospital:User Satisfaction and Factors Affecting Successful Implementation
No full textBackground: Despite the increasing global trend towards e-prescribing, its impact in India is uncertain. Therefore the factors towards successful implementation of e-prescribing system are worth exploring.Objectives: To assess physicians and pharmacists’ satisfaction, the factors that determine their satisfaction and perceptions about the advantages and disadvantages of e-prescribing system.Method: A cross-sectional, anonymous questionnaire survey was administered to physicians and pharmacists. Factors pertaining to reliability, speed, ease of use, adequacy of training and impact on productivity and patient care of the systemwere determined. Two-tailed t tests were used to find the differences in satisfaction level. Simple correlation analysis was used to find the relation between factors and satisfaction level.Results: 389 (57%) physicians and pharmacists responded, of which 323 questionnaires that met inclusion criteria were included for analysis. The users were generally satisfied with e-prescribing system (mean=4.75 on a 7 point scale). The pharmacists were more satisfied than the physicians (95% vs. 75%; pConclusion: Overall the users were satisfied with e-prescribing system; however, senior physicians were more dissatisfied than others. The findings have implications for strategic training, development of additional features and optimize use among dissatisfied users
Electronic Prescribing System in a Teaching Hospital:User Satisfaction and Factors Affecting Successful Implementation
No full textBackground: Despite the increasing global trend towards e-prescribing, its impact in India is uncertain. Therefore the factors towards successful implementation of e-prescribing system are worth exploring.Objectives: To assess physicians and pharmacists’ satisfaction, the factors that determine their satisfaction and perceptions about the advantages and disadvantages of e-prescribing system.Method: A cross-sectional, anonymous questionnaire survey was administered to physicians and pharmacists. Factors pertaining to reliability, speed, ease of use, adequacy of training and impact on productivity and patient care of the systemwere determined. Two-tailed t tests were used to find the differences in satisfaction level. Simple correlation analysis was used to find the relation between factors and satisfaction level.Results: 389 (57%) physicians and pharmacists responded, of which 323 questionnaires that met inclusion criteria were included for analysis. The users were generally satisfied with e-prescribing system (mean=4.75 on a 7 point scale). The pharmacists were more satisfied than the physicians (95% vs. 75%; pConclusion: Overall the users were satisfied with e-prescribing system; however, senior physicians were more dissatisfied than others. The findings have implications for strategic training, development of additional features and optimize use among dissatisfied users
Intercycle Unplanned Hospital Admissions Due to Cisplatin-based Chemotherapy Regimen-induced Adverse Reactions:A Retrospective Analysis
No full textBackground: Cisplatin is a commonly used chemotherapy agent known to induce serious adverse reactions that may require hospital readmission. We aimed to analyze the extent and factors associated with unplanned hospital admissions due to cisplatin-based chemotherapy regimen-induced adverse reactions. Methods: Retrospective review of medical records of those patients who received at least one cycle of chemotherapy with cisplatin-based regimen during a six-month period from March to August 2017. Results: Of the 458 patients who received cisplatin during the study period, 142 patients did not meet inclusion criteria. The remaining 316 patients had a total of 770 episodes of primary admissions for chemotherapy administration. Overall, 187 episodes (24%) of intercycle unplanned hospital admission were recorded of which a major proportion (n=178; 23%) was due to chemotherapy-induced adverse reactions. Underweight patients had higher odds of unplanned admission (OR 1.77, 95% confidence interval [CI] 1.11 to 1.77). Significantly, more number of patients with cancers of head and neck and cancers of musculoskeletal were readmitted (pConclusion: These findings highlight risk factors that help identify high-risk patients and suggest that therapy modifications may reduce hospital readmissions due to cisplatin-based chemotherapy-induced adverse reactions
Facilitators, Barriers, and Potential Impacts of Implementation of e-Pharmacy in India and its Potential Impact on Cost, Quality, and Access to Medicines: Scoping Review
No full textBackgrounde-Pharmacy can potentially solve problems related to the quality of services and products, cost, and access to medicines in low- and middle-income countries. This review aims to understand the facilitators and barriers to the implementation of e-pharmacy in India.
ObjectiveThis scoping review aimed (1) to understand the facilitators and barriers to the use of e-pharmacy in India and (2) to estimate the potential for e-pharmacy in India for improving access to medication, improving the quality of services and medicines, and decreasing costs of medications.
MethodsAll published and gray literature from July 1, 2011, to June 30, 2021, relating to e-pharmacy, was searched from MEDLINE, Scopus, ProQuest, and Google using a systematic search strategy.
ResultsIn total, 1464 titles and abstracts were screened, of which 47 full-texts were included in the review. e-Pharmacy can potentially improve access to medications for remote areas, and old and debilitated individuals. e-Pharmacies can enable lean supply chain management, lower cost, and allow easy tracking of dispensed medicines. There is potential for integration of e-pharmacy services into the national program of Bhartiya Jan Aushadhi Pariyojana. However, the country is not adequately regulated to prevent the growth of illicit e-pharmacies. Lack of global accreditation and internet coverage, digital literacy, and transnational access are other challenges.
ConclusionsE-pharmacy has the potential to improve universal health coverage in India by improving access to medicines and lowering the overall cost of health care. However, future growth will need specific regulations and accreditation mechanisms.
Trial RegistrationOpen Science Forum; https://doi.org/10.17605/OSF.IO/6R9Y
Facilitators and barriers for implementation of E-pharmacy in India and its potential impact on cost, quality and access to drugs : A scoping review
No full textScoping review to understand the potential for use of E-pharmacy services in primary health care system in the context of Indi
Importance of Appropriate Medication Administration in Patients with Nasogastric Feeding Tube
Get PDFSolid dosage forms like modified release and enteric coated formulations are considered inappropriate for nasogastric feeding tube (NGFT) administration due to varying pharmacokinetics which could lead to inadequate therapeutic responses or toxicity. An analysis was conducted to assess the appropriateness of prescribed medicines for NGFT administration in hospital inpatients so that physicians can be sensitized to the importance of this. In this cross-sectional study conducted in a large tertiary care centre, prescription data of in-patients with nasogastric feeding tube (NGFT) were retrieved through electronic pharmacy transactions. Adult patients who were admitted in the hospital for more than one day and were dispensed a NGFT were included. The appropriateness of medicines administered through NGFT was assessed using standard published literature. Details of medicines that were categorized as inappropriate were collated and analysed. In case of inappropriate prescribing, availability of appropriate dosage forms was also determined. A total of 510 patients were found eligible for analyses. Majority of the patients were dispensed at least one inappropriate dosage form. Among the dispensed oral solid dosage forms, 16.38% were found to be inappropriate for NGFT administration. Of these, 21.41% were dispensed on same day as the NGFT, 34.67% were dispensed before the NGFT and were continued throughout the hospital stay and 43.92% were dispensed within or after 24 hours of NGFT dispensation. These findings will improve awareness among healthcare professionals about the need for appropriate administration of oral formulations in patients intubated with NGFT. Keywords: Inappropriate Dosage Forms, Nasogastric Feeding Tube, Appropriate Dosage Forms, Modified Release Formulation
Serious Infection Risk with Systemic Treatments for Psoriasis:A Systematic Review and Network Meta-analysis Combining Randomised and Non-randomised Evidence
No full textINTRODUCTION: Systemic treatments including standard and targeted drugs for psoriasis could increase the risk of serious infections. In this study we assessed the serious infection risk associated with systemic treatments in patients with psoriasis.METHODS: A systematic review of randomised controlled trials (RCTs) and non-randomised studies of interventions (NRSIs) comparing systemic treatments with placebo or each other was performed. Studies included in Medline, Embase, Cochrane register, CINAHL and ClinicalTrials.gov until September 2024 were eligible if at least 50 adults or children with plaque psoriasis were studied. The primary outcome was serious infection defined as any infection resulting in hospitalization, administration of intravenous antibiotics, death or classified as serious by study authors. Two authors independently performed screening for study eligibility. A frequentist network meta-analysis (NMA) was performed using random effects model. RCT, NRSI and combined (RCT and NRSI) networks were created.RESULTS: From 119 eligible RCTs, 76 with at least one serious infection event (n = 39,044) and out of 33 eligible NRSIs, 6 without critical risk of bias (n = 306,762) were included in the NMA. Patients were predominantly male (up to 85%) with a mean age ranging from 13 to 52 years. The RCT network showed no increase in serious infection risk with any drug or drug class when compared with each other. The NRSI network showed higher risk with infliximab and adalimumab compared to several other drugs, especially infliximab vs methotrexate (IRR 2.85; 95% CI 1.48, 5.46), and adalimumab vs ustekinumab (IRR 1.51; 95% CI 1.25, 1.83). In the combined NMA, infliximab and adalimumab were additionally shown to have significantly higher risk than acitretin, bimekizumab, methotrexate, placebo, risankizumab, and secukinumab.CONCLUSIONS: The tumour necrosis factor alpha (TNFα) inhibitors adalimumab and infliximab had higher risk of serious infections in the combined NMA. Our findings may inform clinicians and patients concerned about the risk of emergent serious infection on therapy.</p
