85 research outputs found
Characterization of water and wildlife strains as a subgroup of Campylobacter jejuni using DNA microarrays.
No full textCampylobacter jejuni is the leading cause of human bacterial gastroenteritis worldwide, but source attribution of the organism is difficult. Previously, DNA microarrays were used to investigate isolate source, which suggested a non-livestock source of infection. In this study we analysed the genome content of 162 clinical, livestock and water and wildlife (WW) associated isolates combined with the previous study. Isolates were grouped by genotypes into nine clusters (C1 to C9). Multilocus sequence typing (MLST) data demonstrated that livestock associated clonal complexes dominated clusters C1-C6. The majority of WW isolates were present in the C9 cluster. Analysis of previously reported genomic variable regions demonstrated that these regions were linked to specific clusters. Two novel variable regions were identified. A six gene multiplex PCR (mPCR) assay, designed to effectively differentiated strains into clusters, was validated with 30 isolates. A further five WW isolates were tested by mPCR and were assigned to the C7-C9 group of clusters. The predictive mPCR test could be used to indicate if a clinical case has come from domesticated or WW sources. Our findings provide further evidence that WW C. jejuni subtypes show niche adaptation and may be important in causing human infection
Exploiting tacit knowledge through knowledge management technologies
No full textThe purpose of this paper is to examine the contributions and suitability of the available knowledge management (KM) technologies, including the Web 2.0 for exploiting tacit knowledge. It proposes an integrated framework for extracting tacit knowledge in organisations, which includes Web 2.0 technologies, KM tools, organisational learning (OL) and Community of Practice (CoP). It reviews a comprehensive literature covering overview of KM theories, KM technologies and OL and identifies the current state of knowledge relating to tacit knowledge exploitation. The outcomes of the paper indicate that Internet and Web 2.0 technologies have stunning prospects for creating learning communities where tacit knowledge can be extracted from people. The author recommends that organisations should design procedures and embed them in their Web 2.0 collaborative platforms persuading employees to record their ideas and share them with other members. It is also recommended that no idea should be taken for granted in a learning community where tacit knowledge exploitation is pursued. It is envisaged that future research should adopt empirical approach involving Complex Adaptive Model for Tacit Knowledge Exploitation (CAMTaKE) and the Theory of Deferred Action in examining the effectiveness of KM technologies including Web 2.0 tools for tacit knowledge exploitation
The Metropolitan Region of Campinas, Brazil: applying the technopolis framework
No full textThis paper examines the potential of the Metropolitan Region of Campinas (MRC) for becoming a technopolis. Located an hour from São Paulo, in Southeastern Brazil, the MRC has been internationally recognized as an important world technological center. This paper maps the economic and technological environment of the region and develops an analysis of the strengths, weaknesses, opportunities and threats in the MRC with respect to entrepreneurship and becoming a technopolis. We begin by looking at selected high-technology industry and service sectors as well as the infrastructure supporting technological innovation and entrepreneurship in the form of research institutes, a research university (Unicamp), support groups, and three incubators. We then discuss the results of two surveys of companies associated with Unicamp or one of the incubators to determine the reliance of these companies on the MRC infrastructure for financing and marketing to networking and legal assistance, as well as their policy recommendations for improving entrepreneurship in the region. We conclude that the region is attractive to many companies and has great potential for future success as a technopolis due to its high levels of both hard and smart infrastructure, the strength of support available from a variety of local institutions, and the high level of economic activity in potentially innovative industrial and service sectors. However, there are several ways that the university, incubators, and public policies could better support entrepreneurship in the MRC. Specifically, an increase in public and private partnerships as well as greater capitalization options for start-ups are key areas the region could change to provide support for greater diversification of the start-ups in the area and further development of the MRC as a technopolis.technology-based start-ups; entrepreneurship; innovation; incubation; economic development; Campinas
Lean six sigma in a call centre : a case study
No full textThis paper, a case study, aims to illustrate the application of lean six sigma in a call centre of a service industry corporation. The study draws on process information and primary data from a real project. The study describes improvements in the operation of the call centre attributable to lean six sigma: increase in first-call resolution ratio, reduction in operator turnover and streamlining of processes. The introduction of lean six sigma into the call centre daily operations' management may have organizational benefits. Although lean six sigma has been extremely successful in the last two decades in the manufacturing sector, its applicability to the service sector has been a controversial topic. This study illustrates its application to a fast-growing area of the service sector, assisting companies in identifying areas of development for their call centres
Thrombosis Is Reduced by Inhibition of COX-1, but Unaffected by Inhibition of COX-2, in an Acute Model of Platelet Activation in the Mouse
No full textThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
The workshop as the work: white anti-racism organising in 1960s, 70s, and 80s US social movements
No full textThis thesis explores the rise of anti-racism workshops developed by white activists in various United States social movements from the late 1960s through the mid-1980s. The shifting ideology of the black freedom movement in the late 1960s, from integration to Black Power, transformed white activists‘ place within racial justice struggles. While recent scholarship has begun to turn its attention towards whites‘ ongoing racial justice activities, one of the most radical and widespread of these efforts is consistently overlooked: anti-racism workshops. Increasingly prevalent from the late 1960s through to the diversity-trainings explosion of the 1990s, this thesis demonstrates that these workshops had their roots in the black freedom, women‘s liberation and gay liberation movements. White activists from these movements led these workshops in order to examine white racial domination and privilege within both leftist social movements and larger US society.
Analysing case studies from the black freedom, women‘s liberation and gay liberation/rights movements, this thesis explores the foundational assumptions of anti-racism workshops. It seeks to explain how and why these efforts sought to frame race and racism as issues of knowledge and consciousness and why such efforts constituted radical praxis. It is argued that early anti-racism workshops were pedagogical projects that sought to confront the racial ignorance that structured the lives of whites in the US, including progressives and their liberation movements. This thesis draws attention to the efficacy and power of these workshops in terms of their epistemological effects, in the transformations they brought about in whites‘ understanding, or awareness, of racial realities
Talking Shit: getting the message across
No full textMasters dissertation submitted in September 2011
Roadmap for cardiovascular education across the European Society of Cardiology: inspiring better knowledge and skills, now and for the future
No full textAimsThe provision of high-quality education allows the European Society of Cardiology (ESC) to achieve its mission of better cardiovascular practice and provides an essential component of translating new evidence to improve outcomes.Methods and resultsThe 4th ESC Education Conference, held in Sophia Antipolis (December 2016), brought together ESC education leaders, National Directors of Training of 43 ESC countries, and representatives of the ESC Young Community. Integrating national descriptions of education and cardiology training, we discussed innovative pathways to further improve knowledge and skills across different training programmes and health care systems. We developed an ESC roadmap supporting better cardiology training and continued medical education (CME), noting: (i) The ESC provides an excellent framework for unbiased and up-to-date cardiovascular education in close cooperation with its National Societies. (ii) The ESC should support the harmonization of cardiology training, curriculum development, and professional dialogue and mentorship. (iii) ESC congresses are an essential forum to learn and discuss the latest developments in cardiovascular medicine. (iv) The ESC should create a unified, interactive educational platform for cardiology training and continued cardiovascular education combining Webinars, eLearning Courses, Clinical Cases, and other educational programmes, along with ESC Congress content, Practice Guidelines and the next ESC Textbook of Cardiovascular Medicine. (v) ESC-delivered online education should be integrated into National and regional cardiology training and CME programmes.ConclusionThese recommendations support the ESC to deliver excellent and comprehensive cardiovascular education for the next generation of specialists. Teamwork between international, national and local partners is essential to achieve this objective
Of the Helmholtz Club, South-Californian seedbed for visual and cognitive neuroscience, and its patron Francis Crick
No full textTaking up the view that semi-institutional gatherings such as clubs, societies, research schools, have been instrumental in creating sheltered spaces from which many a 20th-century project-driven interdisciplinary research programme could develop and become established within the institutions of science, the paper explores the history of one such gathering from its inception in the early 1980s into the 2000s, the Helmholtz Club, which brought together scientists from such various research fields as neuroanatomy, neurophysiology, psychophysics, computer science and engineering, who all had an interest in the study of the visual system and of higher cognitive functions relying on visual perception such as visual consciousness. It argues that British molecular biologist turned South Californian neuroscientist Francis Crick had an early and lasting influence over the Helmholtz Club of which he was a founding pillar, and that from its inception, the club served as a constitutive element in his long-term plans for a neuroscience of vision and of cognition. Further, it argues that in this role, the Helmholtz Club served many purposes, the primary of which was to be a social forum for interdisciplinary discussion, where ‘discussion’ was not mere talk but was imbued with an epistemic value and as such, carefully cultivated. Finally, it questions what counts as ‘doing science’ and in turn, definitions of success and failure—and provides some material evidence towards re-appraising the successfulness of Crick’s contribution to the neurosciences
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