11,764 research outputs found
Service-oriented models for audiovisual content storage
No full textWhat are the important topics to understand if involved with storage services to hold digital audiovisual content? This report takes a look at how content is created and moves into and out of storage; the storage service value networks and architectures found now and expected in the future; what sort of data transfer is expected to and from an audiovisual archive; what transfer protocols to use; and a summary of security and interface issues
sj-pdf-1-ctj-10.1177_17407745211032909 – Supplemental material for Cost-effective clinical trial design: Application of a Bayesian sequential model to the ProFHER pragmatic trial
No full textSupplemental material, sj-pdf-1-ctj-10.1177_17407745211032909 for Cost-effective clinical trial design: Application of a Bayesian sequential model to the ProFHER pragmatic trial by Martin Forster, Stephen Brealey, Stephen Chick, Ada Keding, Belen Corbacho, Andres Alban, Paolo Pertile and Amar Rangan in Clinical Trials</p
AC-6-U.S. Naval Planes Flying in Formation, Langley Field, VA/Thank-You Card from Stephen Tury to the Hungarian Defense Council.
No full textThis postcard, which depicts U.S. Naval planes flying in formation, was sent to the Hungarian Defense Council by Private Stephen Tury. The Council was organized in New Brunswick by leaders of local Hungarian churches and societies. During the Second World War it sent supplies, such as the carton of cigarettes Tury is thanking it for, to members of the military of Hungarian descent from the New Brunswick area
Author Stephen Flynn Discusses Resiliency
No full textCenter for Homeland Defense and Security, PRESS RELEASESOn September 25, Author Stephen E. Flynn stopped by the Center’s National Capital Region campus to speak with CHDS Master’s degree students about his latest book, answer questions and discuss..
Letter from Carl Hayden to Stephen Mather, National Park Service
No full textLetter from Carl Hayden to Stephen Mather regarding the sale of Bass properties
Letter from Carl Hayden to Stephen Mather, National Park Service
No full textLetter from Carl Hayden to Stephen Mather requesting that congress pay W. W. Bass the sum of twenty-five thousand dollars for his properties
Stephen Graham Jones - Sowell Conference 2017
No full textStephen Graham Jones, University of Colorado-Boulder, author of "Mongrels" and "Growing Up Dead in Texas
Cost-effective clinical trial design:application of a Bayesian sequential model to the ProFHER pragmatic trial
No full textBackground/Aims: There is growing interest in the use of adaptive designs to improve the efficiency of clinical trials. We apply a Bayesian decision-theoretic model of a sequential experiment using cost and outcome data from the ProFHER pragmatic trial. We assess the model's potential for delivering value-based research. Methods: Using parameter values estimated from the ProFHER pragmatic trial, including the costs of carrying out the trial, we establish when the trial could have stopped, had the model's value-based stopping rule been used. We use a bootstrap analysis and simulation study to assess a range of operating characteristics, which we compare with a fixed sample size design which does not allow for early stopping. Results: We estimate that application of the model could have stopped the ProFHER trial early, reducing the sample size by about 14%, saving about 5% of the research budget and resulting in a technology recommendation which was the same as that of the trial. The bootstrap analysis suggests that the expected sample size would have been 38% lower, saving around 13% of the research budget, with a probability of 0.92 of making the same technology recommendation decision. It also shows a large degree of variability in the trial's sample size. Conclusions: Benefits to trial cost stewardship may be achieved by monitoring trial data as they accumulate and using a stopping rule which balances the benefit of obtaining more information through continued recruitment with the cost of obtaining that information. We present recommendations for further research investigating the application of value-based sequential designs
Letter from Stephen Mather, National Park Service to Carl Hayden
No full textLetter from Stephen Mather to Carl Hayden regarding the sale of Bass properties to the Santa Fe Railroad Company
Letter from Stephen T. Mather to Carl Hayden
No full textLetter from Stephen Mather to Carl T. Hayden regarding automobile regulations within Grand Canyon National Park
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