1,721,043 research outputs found
Genital-peritoneal tuberculosis: A case with different diagnostic work up
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D-chiro inositol phosphoglycan (IPG-P) as a potential urinary marker to predict preeclampsia
Preeclampsia is a pathological condition that can complicate human pregnancy with a frequency between 2 and 7% of healthy nulliparous women worldwide. Inositol phosphoglycans P type (IPG-P) are phospholipids that exert an insulin mimetic activity and increase during pregnancy in fetal and maternal compartments with a clear higher concentration in pregnancies complicated by preeclampsia. A comprehensive review of the literature was performed to identify the most relevant studies about this topic. Many authors in the last decades investigated IPG-P modifications in different compartments of preeclamptic pregnancies, finding an increased concentration of this phosphoglycans in villous stroma, cord blood, amniotic fluid and in maternal urines even weeks before the clinical onset of the disease. According to these findings, urinary IPG-P can be a reliable test to identify women at risk of preeclampsia weeks before the clinical presentation of the maternal syndrome. This test showed a good sensitivity and specificity and it is based on a low-cost and direct assay that makes this method of great interest especially in low-and middle-income countries. Further longitudinal studies in different ethnic groups are warranted to demonstrate a transverse efficacy of the test
Ten-year survival in patients with endometrial adenoacanthoma and endometrial adenocarcinoma with malignant squamous cell differentiation
Objectives: It is acknowledged that squamous differentiation in the endometrial adenocarcinoma does not affect the outcome of type I cancer. However, it has been recently reported that the so-called shadow cell differentiation is likely present in endometrial adenoacanthomas. As the shadow cells differentiation suggests a caspase-independent cell death, based on the previous reports it can be hypothesized that the endometrial adenoacanthoma would have a better prognosis than the endometrial adenocarcinoma with squamous differentiation. Methods: From a database of 829 endometrial cancer, 34 endometrial adenoacanthomas and 18 endometrial adenocarcinomas with malignant squamous differentiation were assessed. The Kaplan-Meier curves were generated and compared for endometrial adenoacanthomas and endometrial adenocarcinomas with malignant squamous differentiation. Results: the 10-year survival in patients with adenocarcinoma with malignant squamous differentiation is significantly lower than the survival in patients with adenoacanthoma. Advanced stage (2009 FIGO II or over) was more likely found in adenocarcinoma with malignant squamous differentiation at the surgery time. Matching groups for the FIGO stage, there were no difference in overall survival. Conclusion: patients with endometrial adenoacanthoma have a better prognosis than patients with endometrial adenocarcinoma with malignant squamous differentiation probably because of the earlier stage diagnosis
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Complete work-up for the management of retained products of conception
Retained products of conception represent an uncommon complication after miscarriage, planned termination of pregnancy, term spontaneous vaginal delivery or caesarean section. The aim of this study was to review the diagnostic and therapeutic management of this condition, according to the current literature, in order to assess patients correctly and reduce the number of unnecessary procedures with all their consequences. This updated review of the literature explores the pathophysiology, clinical features, diagnostic investigations, and treatment options for this complex condition. Laboratory tests are normal in most cases and have limited utility. Gray scale and Color Doppler ultrasound are the first line modality for the diagnosis of RPOC, even if ultrasound features alone should not be considered as conclusive, having an overall reported sensitivity of 44-85% and a specificity of 88-94%. Hysteroscopic resection of placental remnants, in absence of electricity use, seems to be the best treatment option with low risks and less complications related to fertility. Diagnosis and correct management of RPOC remain a major clinical challenge, since no clearly defined diagnostic criteria and treatment guidelines still exist. Hysteroscopic resection seems to be a good option, but well-designed randomized controlled trials are needed to define the best treatment modality
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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