170,097 research outputs found

    Letter to Wiley Branton

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    Letter from Virgil Blossom to Wiley Branton, chairman of the Legal Redress Committee of the Arkansas chapter of the NAACP. The letter is in response to a petition regarding development of an early integration plan for Little Rock schools.August 21, 1954 Mr. William G. Cooper President Little Rock School Board Little Rock, Arkansas Re: Petition on Desegregation Dear Sir: The enclosed Petition is a copy of the original Petition on file in my office and signed by the patrons of your school district. The Petition requests a hearing with your school board to discuss plans for desegregation in accordance with the Supreme Court's decision. The patrons of your community have requested the aid of the National Association for the Advancement of Colored People in working with the board and they have requested that Mr. J. C. Crenchaw, 702 West 9th Street, Little Rock, be notified of the date of the meeting on this Petition and that he be invited to be present. As Chairman of the Legal Redress Committee of the State Conference of Branches of the NAACP, I hereby re- quest a hearing before your school board on behalf of the patrons of your district and am asking that you notify meof the date of the hearing. I am hoping that your board will not adopt a "wait and see" attitude with reference to the Supreme Court de- cision and that they will want to earnestly make plans now to comply with the ruling as to the time and method of enforcement yet to be announced. Very truly yours, [signature enclosed] Wiley A. Branton, Chairman Legal Redress Committee, NAACP wab/lm Enclosures: 1 Copy to: Mr. Virgil T. Blosso

    Correspondence from W. C. Patton to Wiley Branton, June 30, 1962

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    A memorandum sent to Wiley A. Branton, executive director of the Voter Education Project, regarding barriers to voting. 1 page

    Correspondence from W. C. Patton to Wiley A. Branton, June 30, 1962

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    A memorandum sent to Wiley A. Branton, executive director of the Voter Education Project, regarding newspaper advertisements for voter registration. 1 page

    C. Eric Lincoln at the American Embassy in Spain, 1965

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    C. Eric Lincoln shakes the hand of Ambassador Angier Biddle Duke as Wiley Branton looks on at the American Embassy Madrid, Spain. Branton and Lincoln were guests at the Embassy.The Atlanta University Center Robert W. Woodruff Library acknowledges the generous support of the National Endowment for Humanities - Humanities Collections and Reference Resources Implementation Project Grant in supporting the processing and digitization of a number of its major archival collections as part of the project: Spreading the Word: Expanding Access to African American Religious Archival Collections at the Atlanta University Center Robert W. Woodruff Library.</em

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Mitomycin C in highly myopic eyes - Author reply

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    Ophthalmology. 2005 Feb;112(2):208-18; discussion 219. Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes. Gambato C, Ghirlando A, Moretto E, Busato F, Midena E. SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy. Abstract PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes. DESIGN: Prospective, double-masked, randomized clinical trial. PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia. METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months). MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH. RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively). CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK. Comment in Ophthalmology. 2006 Feb;113(2):357; author reply 357-8

    Characterization of Physical, Spectral and Thermal Properties of Biofield Treated 1,2,4-Triazole

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    Triazoles are an important class of compounds used as core molecule for the synthesis of many pharmaceutical drugs. The objective of the present research was to investigate the influence of biofield treatment on physical, spectral and thermal properties of 1,2,4-triazole. The study was performed in two groups, control and treatment. The control group remained as untreated, and biofield treatment was given to treatment group. The control and treated 1,2,4-triazole were characterized by X-ray diffraction (XRD), Differential Scanning Calorimetry (DSC), Thermo Gravimetric analysis (TGA), Surface area analyzer, and Fourier transform infrared (FT-IR) spectroscopy. XRD analysis revealed a decrease in unit cell volume of treated 1,2,4-triazole (662.08 10-24 cm3) as compared to control sample (666.34 10-24 cm3). Similarly, a decrease in molecular weight of treated 1,2,4-triazole (69.78 g/mol) with respect to control (70.23 g/mol) was observed. Additionally, a substantial decrease in crystallite size (G) was observed in treated 1,2,4-triazole by 16.34% with respect to control. DSC analysis showed a slight increase in melting temperature of treated 1,2,4-triazole (124.22°C) as compared to control (123.76°C). Moreover, a significant increase in latent heat of fusion was noticed in treated 1,2,4-triazole by 21.16% as compared to control sample. TGA analysis showed a significant increase in maximum thermal decomposition temperature (Tmax) of treated 1,2,4-triazole (213.40°C) as compared to control (199.68°C). Surface area analysis using BET showed a substantial increase in surface area of the treated compound by 13.52% with respect to control. However, FT-IR analysis showed no structural changes in treated 1,2,4-triazole with respect to control. Overall, the result showed significant alteration of physical and thermal properties of the treated 1,2,4-triazole with respect to control.Trivedi MK, Tallapragada RM, Branton A, Trivedi D, Nayak G, et al. (2015) Characterization of Physical, Spectral and Thermal Properties of Biofield Treated 1,2,4-Triazole. J Mol Pharm Org Process Res 3: 128. doi:10.4172/2329-9053.100012

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    CONFORMATION AND ELASTICITY OF THE ISOLATED RED-BLOOD-CELL MEMBRANE SKELETON

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    We studied the structure and elasticity of membrane skeletons from human red blood cells (RBCs) during and after extraction of RBC ghosts-with nonionic detergent. Optical tweezers were used to suspend individual cells inside a flow chamber, away from all surfaces; this procedure allowed complete exchange of medium while the low-contrast protein network of the skeleton was observed by high resolution, video-enhanced differential interference-contrast (DIC) microscopy. Immediately following extraction in a 5 mM salt buff er, skeletons assumed expanded, nearly spherical shapes that were uncorrelated with the shapes of their parent RBCs. Judging by the extent of thermal undulations and by their deformability in small flow fields, the bending rigidity of skeletons was markedly lower than that of either RBCs or ghosts. No further changes were apparent in skeletons maintained in this buffer for up to 40 min at low temperatures (T < 10-degrees-C), but skeletons shrank when the ionic strength of the buffer was increased. When the salt concentration was raised to 1.5 M, shrinkage remained reversible for approximately 1 min but thereafter became irreversible. When maintained in 1.5 M salt buffer for longer periods, skeletons continued to shrink, lost flexibility, and assumed irregular shapes: this rigidification was irreversible. At this stage, skeletons closely resembled those isolated in standard bulk preparations. We propose that the transformation to the rigid, irreversibly shrunken state is a consequence of spectrin dimer-dimer reconnections and that these structural rearrangements are thermally activated. We also measured the salt-dependent size of fresh and bulk extracted skeletons. Our measurements suggest that, in situ, the spectrin tethers are flexible, with a persistence length of approximately 10 nm at 150 mM salt

    CONFORMATION AND ELASTICITY OF THE ISOLATED RED-BLOOD-CELL MEMBRANE SKELETON

    No full text
    We studied the structure and elasticity of membrane skeletons from human red blood cells (RBCs) during and after extraction of RBC ghosts-with nonionic detergent. Optical tweezers were used to suspend individual cells inside a flow chamber, away from all surfaces; this procedure allowed complete exchange of medium while the low-contrast protein network of the skeleton was observed by high resolution, video-enhanced differential interference-contrast (DIC) microscopy. Immediately following extraction in a 5 mM salt buff er, skeletons assumed expanded, nearly spherical shapes that were uncorrelated with the shapes of their parent RBCs. Judging by the extent of thermal undulations and by their deformability in small flow fields, the bending rigidity of skeletons was markedly lower than that of either RBCs or ghosts. No further changes were apparent in skeletons maintained in this buffer for up to 40 min at low temperatures (T < 10-degrees-C), but skeletons shrank when the ionic strength of the buffer was increased. When the salt concentration was raised to 1.5 M, shrinkage remained reversible for approximately 1 min but thereafter became irreversible. When maintained in 1.5 M salt buffer for longer periods, skeletons continued to shrink, lost flexibility, and assumed irregular shapes: this rigidification was irreversible. At this stage, skeletons closely resembled those isolated in standard bulk preparations. We propose that the transformation to the rigid, irreversibly shrunken state is a consequence of spectrin dimer-dimer reconnections and that these structural rearrangements are thermally activated. We also measured the salt-dependent size of fresh and bulk extracted skeletons. Our measurements suggest that, in situ, the spectrin tethers are flexible, with a persistence length of approximately 10 nm at 150 mM salt
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