1,720,958 research outputs found
Histological alterations by a diet containing seeds of Garcinia kola: effect on liver, kidney, and intestine in the rat.
No full textHistological examination of liver, kidney, and duodenum of rats fed a diet containing 10% (w/w) dry powdered seeds of Garcinia kola for 6 weeks revealed cellular changes that were not observed in pair-fed control animals. The main cellular changes observed in the rats fed on Garcinia kola diet included vacuolation of duodenal villous epithelial cells, numerous intracytoplasmic vacuoles in hepatocytes, and mild hydropic degeneration in cells of the renal proximal tubular epithelium. These changes are probably due to the flavonoids contained in G. kola seeds
Calcium ethylenediaminetetraacetate toxicity in the rat: ultrastructural effects on skin collagen.
No full textThe effect of calcium ethylenediaminetetraacetate (CaEDTA) i.v. infusion on skin ultrastructure was studied in the rat with the aid of transmission electron microscopy. High magnification electron micrographs of collagen fibrils were analysed with a computer aided image analyser, in terms of the Gaussian distribution of fibril diameter and the distance between cross striations of collagen fibrils (D-spacing). CaEDTA caused marked depletion of collagen fibrils in the skin. The collagen fibrils from CaEDTA treated rats exhibited significant increases in D-spacing (about 30%) and diameter (about 40%) compared to saline treated controls. These findings are consistent with earlier published biochemical data indicating that CaEDTA enhances collagen degradation in the rat
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Effects of crude alkaloid extract of Garcinia Kola seed on serum gonadotrophins and testosterone levels in male rats
Full text linkThe effects of daily oral administration of alkaloid extract of Garcinia kola seed (GKA) at 1500mg/kg on serum levels of luteinizing hormone (LH), follicle stimulating hormone (FSH) and testosterone (TST) were studied in male rats (100-150g) for six to seven weeks. The pair-fed control rats received oral doses of methanolic saline daily for six to seven weeks. The animals were injected i.m. with Menotrophin (1.07IU/kg) or Testosterone (2.6mg/kg) during the seventh week of receiving GKA or following six weeks of treatment with GKA. The control rats were injected with normal saline or olive oil vehicles during the seventh week. At the end of the seventh week, all animals were exsanguinated to collect serum for hormone assays. Results showed that levels of serum gonadotrophins (LH and FSH) were significantly elevated, while serum TST levels were markedly reduced, compared to the pair-fed controls.RUNNING TITLE: G. kola alkaloid effects on endocrine organ
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Effect Of Dietary Garcinia Kola Seed On Selected Serum Electrolytes And Trace Metals In Male Albino Rats
Full text linkSummary: The effects of various doses of dietary intake of Garcinia kola seed powder [incorporated in animal feed at levels of 5% w/w, 10% w/w and 20% w/w and fed daily for six weeks] on serum levels of selected electrolytes (K+, Na+, CI-, HCO- 3, Mg2+ and Ca2+) and trace metals (Cu2+ Zn2+ and Mn2+) were studied in male albino rats (100-150g body wt). The pair –fed controls received basal feed diet daily for six weeks. Results showed a significant (P< 0.05) dose dependent elevation of serum CI-, HCO-3, Ca2+, Mg2+, Cu2+, Zn2+ and Mn2+. These findings point to a possible relationship with already documented histopathology of various organs (such as the gonads) induced by Garcinia kola seed. It is also conjectured that the documented antibacterial, anti-inflammatory, anti-spasmodic, antidiabetic and antifertility effects of Garcinia kola seed may have underlying involvement of alterations in body levels of trace metals and electrolytes
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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