126,021 research outputs found
Remission of histiocytic ulcerative colitis in Boxer dogs correlates with eradication of invasive intramucosal Escherichia coli
BACKGROUND: Historically, histiocytic ulcerative (HUC) (or granulomatous) colitis of Boxer dogs was considered an idiopathic immune-mediated disease with a poor prognosis. Recent reports of dramatic responses to enrofloxacin and the discovery of invasive Escherichia coli within the colonic mucosa of affected Boxer dogs support an infectious etiology. HYPOTHESIS: Invasive E. coli is associated with colonic inflammation in Boxer dogs with HUC, and eradication of intramucosal E. coli correlates with clinical and histologic remission. ANIMALS: Seven Boxer dogs with HUC. METHODS: Prospective case series. Colonic biopsies were obtained at initial evaluation in 7 dogs, and in 5 dogs after treatment with enrofloxacin. Biopsies were evaluated by standardized histopathology, and fluorescence in situ hybridization (FISH) with probes to eubacteria and E. coli. RESULTS: Intramucosal E. coli was present in colonic biopsies of 7/7 Boxers with HUC. Clinical response was noted in all dogs within 2 weeks of enrofloxacin (7 + or - 3.06 mg/kg q24 h, for 9.5 + or - 3.98 weeks) and was sustained in 6 dogs (median disease-free interval to date of 47 months, range 17-62). FISH was negative for E. coli in 4/5 dogs after enrofloxacin. E. coli resistant to enrofloxacin were present in the FISH-positive dog that relapsed. CONCLUSIONS AND CLINICAL RELEVANCE: The correlation between clinical remission and the eradication of mucosally invasive E. coli during treatment with enrofloxacin supports the causal involvement of E. coli in the development of HUC in susceptible Boxer dogs. A poor response to enrofloxacin treatment might be due to colonization with enrofloxacin-resistant E. coli
A német boxer jelenlegi helyzete Magyarországon
A német boxer fajta standardjáról, történetéről, táplálkozásáról, kiállításon való részvételének szabályairól, minősítéséről, az utódok színeinek öröklődéséről és a visszakeresztezéséről szól.Állattenyésztő mérnökBSc/B
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Pre-Boxer Taiyuan Cathedral Complex
Pre-Boxer Taiyuan Cathedral Complex. Taiyuan, China. B/W Photo.https://digitalcommons.whitworth.edu/cmh_friars_minor/1077/thumbnail.jp
Boxer Jesse Rogers in Fighting Stance, B
Boxer Jesse Rogers wearing headgear and boxing gloves in a fighting stance.https://digitalcommons.usf.edu/gandy/4622/thumbnail.jp
Obituary of James B. Peters Sr., 83, of Eastport, a professional boxer in the 19
Obituary of James B. Peters Sr., 83, of Eastport, a professional boxer in the 1920s and 1930s
Obituary of James B. Peters Sr., 83, of Eastport, a professional boxer in the 19
Obituary of James B. Peters Sr., 83, of Eastport, a professional boxer in the 1920s and 1930s
Post-Boxer Reconstruction of Taiyuan Cathedral Complex
Post-Boxer reconstruction of Taiyuan Cathedral Complex. Taiyuan, China. B/W Photo.https://digitalcommons.whitworth.edu/cmh_friars_minor/1075/thumbnail.jp
Franciscan Martyrs of the Boxer Uprising
Franciscan Martyrs of the Boxer Uprising. B/W Photo of a Print.https://digitalcommons.whitworth.edu/cmh_friars_minor/1082/thumbnail.jp
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