1,720,992 research outputs found
La Riabilitazione dell’emiplegia in letteratura: dai meccanismi di integrazione neurofisiologica al processo di elaborazione del programma di riabilitazione. Analisi critica di alcune scuole di neuroriabilitazione
No full textL'articolo prevede l'analisi critica dei principali approcci riabilitativi che si sono interessati di emiplegia. Spesso infatti si rischia di utilizzare sistematicamente una metodica, limitando l'ampio spettro di scelta di strumenti riabilitativi di cui si dispone.
L'articolo prevede la sintesi prodotta dalla revisione della letteratura riguardante cinque autori: Brunnstrom, Vojta, Kabat, Bobath, Perfetti. In particolare sono stati analizzati i seguenti aspetti: i livelli anatomo-funzionali del sistema nervoso centrale a cui l'autore fa riferimento, i disturbi del movimento conseguenti al danno neurologico da lui individuati, il metodo di valutazione e classificazione che adotta e quali facilitazioni propone come soluzioni terapeutiche
Cultural heritage diagnostics with electrochemical immunosensors based on nanoelectrode ensembles
No full textVariability in bitter taste perception and correlation with SNP in TAS2R38 gene in different student population
No full textPeople vary widely in their sensitivities to bitter compounds. The PTC gene, TAS2R38 on chromosome 7, consists a single coding exon which encodes a G-protein-coupled receptor. The taster subject contains a proline at position 49, an alanine at position 262. and a valine at position 296 (PAV form), while the no taster contains an alanine, a valine, and an isoleucine at these 3 positions, respectively (AVI form).These two forms depend on three single nucleotide polymorphisms (SNP). By providing students with paper soaked in different solutions of PTC it was been possible to assess the individual threshold of bitterness sensitivity. DNA was extracted from saliva, and following PCR amplification, SNP were evaluated by gel electrophoresis. A questionnaire about life style and diet was also administered to students for possible association studies with the genetic polymorphism. Our goal is to investigate correlations as a function of individual sensitivities to several bitter compounds representative of different chemical classes and than infer the number and variety of potential bitterness transduction system
Single tube genotyping of GSTM1, GSTT1 and TP53 polymorphisms by multiplex PCR
No full textGlutathione S-transferases (GST) are enzymes involved in the conjugation of a number of human carcinogens, while p53 tumour suppressor gene is the most frequently mutated gene identified till now in human neoplasias. Typically, GSTM1 and GSTT1 genotyping are performed together, with several different protocol described and sometimes with the risk of misclassification due to "false negative", depending on the internal positive control employed. Here, we report a modification of the classical multiplex polymerase chain reaction (PCR) method, allowing the genotyping of GSTM1, GSTT1, together with a polymorphism within the intron 3 of TP53 tumour suppressor gene (a 16 base pairs (bp) duplication) in a single tube, with an appropriate internal positive control. To test the applicability of the method, the frequencies of the deleted alleles of GSTM1 and GSTT1 (null genotypes), and the 16 bp duplication of TP53 gene were assayed in a series of Caucasian DNA samples
Le garanzie di effettività dei LEA al tempo della crisi
No full textIl saggio indaga gli effetti della crisi sugli strumenti di tutela dell'effettività dell'accesso alle prestazioni sanitarie e gli effetti del loro sviamento alla finalità di contenimento della spesa pubblic
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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