197,124 research outputs found
Senses of Self. Approaches to Pre-Reflective Self-Consciousness
No full textFrank M, Borner M, Williford KW, eds. Senses of Self. Approaches to Pre-Reflective Self-Consciousness. ProtoSociolgy. An International Journal and Interdisciplinary Project. Vol 36.; Unpublished
À propos de Thaumaloxena Wasmanni Breddin et Borner, 1904, Insecte Diptère commensal des Termites (Voyage de M. P. P. Grasse en Afrique occidentale française, 1934)
No full textPoisson Raymond A. À propos de Thaumaloxena Wasmanni Breddin et Borner, 1904, Insecte Diptère commensal des Termites (Voyage de M. P. P. Grasse en Afrique occidentale française, 1934). In: Bulletin de la Société entomologique de France, volume 42 (13-14),1937. pp. 201-208
À propos de Thaumaloxena Wasmanni Breddin et Borner, 1904, Insecte Diptère commensal des Termites (Voyage de M. P. P. Grasse en Afrique occidentale française, 1934)
No full textPoisson Raymond A. À propos de Thaumaloxena Wasmanni Breddin et Borner, 1904, Insecte Diptère commensal des Termites (Voyage de M. P. P. Grasse en Afrique occidentale française, 1934). In: Bulletin de la Société entomologique de France, volume 42 (13-14),1937. pp. 201-208
[Molecular targets in colon cancer]
No full textColorectal cancer is the second leading cause of cancer death in Switzerland. The nihilism that dominated the treatment of these patients for decades has been replaced by a measure of enthusiasm, given recent therapeutic advances. New anticancer drugs such as irinotecan and oxaliplatin have changed the standard chemotherapy treatment of metastatic colorectal cancer. However, the real hype has come from molecular targeted therapy. Identification of cellular processes characteristic of colon cancer has permitted therapeutic targeting with favorable therapeutic index. Inhibition of the epidermal growth factor receptor in the clinic has provided proof of principle that interruption of signal transduction cascades in patients has therapeutic potential. Angiogenesis, especially the vascular endothelial growth factor pathway, has been proven to be another highly successful molecular target. In this article, we will review molecular targets, which are under active clinical investigation in colon cancer
Coloradoa heinzei Borner
No full textColoradoa heinzei (Borner) (Figs. 14–20 & 22, Table 2) Lidaja heinzei Borner, 1952 Apterous viviparous female (based on 12 examined specimens): Body color green; small, 0.77–0.88 mm long; apices of antenna and SIPH, and tarsi rather dark; base of SIPH and cauda pale; dorsal hairs numerous, fanshaped; marginal tubercles absent; frons slightly convex, lateral frontal tubercles undeveloped; antenna 6 segmented, 0.53–0.63 times as long as body; secondary rhinaria absent; PT 1.44–1.76 times longer than the ANTVIb; URS pointed with concave margins, 1.24–1.40 times longer than 2 HT; first tarsal segments with 3 – 3 – 2 hairs; SIPH subcylindrical about 0.09 times as long as body, 0.78 –1.0 times as long as cauda, 0.83–0.97 times as long as URS; cauda triangular, slightly constricted at base, 0.88–1.06 times as long as URS, with 5 hairs. In this paper C. heinzei has been redescribed because Iranian specimens have some morphological differences from previously described materials by Stroyan (1979) and Heie (1992). These differences are as follows: Body length of Iranian C. heinzei is 0.77 – 0.88 mm while in the other materials it is 1.0 – 1.65 mm. The other difference is ratio between SIPH and cauda length. In Iranian samples it is between 0.78 – 1.0 times but in other materials the range is 0.58 – 0.79 times. Based on Stroyan (1979) SIPH is 0.64 – 0.91 times and Cauda 1.0– 1.3 times as long as URS, but in our specimens these ratios is between 0.83 – 0.97 and 0.88 – 1.06 times respectively. Based on Heie (1992) the antenna is 0.6–0.7 times and SIPH about 0.07 times as long as body but in Iranian specimens these are 0.53 – 0.63 and 0.09 times respectively. These morphological differences especially smaller body size in Iranian materials might be because of development on an unfavourable host or local adaptation under conditions of geographical separation. Host and distribution. Coloradoa heinzei collected on Artemisia aucheri (Asteraceae) in 6 October 2006. The species is known from one locality in Sekonge, east of Kerman Province, Iran, N 30 ° 00´23.3 ´´ E 57 ° 28´19.9 ´´, Altitude: 2474 m. TABLE 2. Biometric data of Coloradoa heinzei . Character Apterous vivipara (n= 12) Length (mm) Body 0.77–0.88 Antenna 0.45–0.49 ANTIII 0.07–0.09 ANTIV 0.05–0.06 ANTV 0.07 ANTVIb 0.07–0.08 PT 0.12–0.13 URS 0.07–0.09 2 HT 0.06 SIPH 0.07 Cauda 0.07–0.09 No. of hairs Cauda 5 No. of rhinaria ANTIII 0 ANTIV 0 ANTV 0Published as part of Mehrparvar, Mohsen & Rezwani, Ali, 2007, A new species of Macrosiphoniella and redescription of Coloradoa heinzei (Hemiptera: Sternorrhyncha: Aphididae) as a new record in Iran, pp. 61-68 in Zootaxa 1634 on pages 65-68, DOI: 10.5281/zenodo.17947
Ferric chloride/methanol in the preparation of triphenylene-based discotic liquid crystals:The synthesis of triphenylene‐based discotic mesogens New and improved routes
No full textA Commentary on the paper ''The synthesis of triphenylene-based discotic mesogens. New and improved routes'', by N. Boden, R. C. Borner, R. J. Bushby, A. N. Cammidge and M. V. Jesudason. First published in Liquid Crystals, 15, 851-858 (1993)
5-Fluorouracil as protracted continuous intravenous infusion can be added to full-dose docetaxel (Taxotere®)–cisplatin in advanced gastric carcinoma: a phase I–II trial
No full textBackground: A phase I-II multicenter trial was conducted to define the maximum tolerated dose (MTD) according to tolerance and toxicity (primary objective), as well as to describe the clinical activity, in terms of response and survival (secondary objectives), of a combination of 5-fluorouracil (5-FU) in protracted continuous intravenous infusion (p.i.v.) with docetaxel and cisplatin for patients with advanced gastric cancer.
Patients and methods: Patients with measurable unresectable and/or metastatic gastric carcinoma, World Health Organization performance status less than or equal to1, normal hematological and renal functions, adequate hepatic function and not pretreated for advanced disease by chemotherapy, received up to eight cycles of a combination of docetaxel on day 1, cisplatin on day 1 and 5-FU p.i.v. on days 1-14 (TCF) every 3 weeks, which was escalated up to the MTD, defined by the occurrence of dose-limiting toxicity in two patients in one dose level.
Results: Fifty-two patients were accrued and treated (43 in the phase I part of the trial and nine additional at the recommended dose level). A median of five cycles/patient was given. The recommended dose of TCF was docetaxel 85 mg/m(2) on day 1, cisplatin 75 mg/m(3) on day 1 and 5-FU p.i.v. 300 mg/m(2) /day on days 1-14. Grade greater than or equal to3 toxicities were neutropenia 79%, alopecia 46%, fatigue 23%, mucositis 10%, diarrhea 19%, nausea/vomiting 13%, neurological 4% and palmar-plantar 2%. Ten non-fatal febrile neutropenia episodes were recorded in eight patients. There were no treatment-related deaths. Among 41 patients with measurable disease (79%), we observed one complete and 20 partial responses for an overall intent-to-treat response rate of 51% (95% confidence interval 35-67%). Five patients (20%) had stable disease for greater than or equal to12 weeks (four cycles). The median overall survival was 9.3 months.
Conclusions: 5-FU p.i.v. at 300 mg/m(2)/day for 2 weeks out of three could be safely added to the docetaxel-cisplatin (TC) combination, but the dose of docetaxel had to be reduced to 75 mg/m(2) in a subsequent phase 11 trial. This drug regimen seems to be very active in advanced gastric cancer. Comparison with both TC and ECF in a randomized SAKK trial is ongoing
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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