1,720,956 research outputs found
Design and development of a PVA composite scaffold for peripheral nerve regeneration
Full text linkThe peripheral nerve injuries represent 2.8% of the total annual trauma. More than 360.000 people at year in the U.S.A. and more than 300.000 in Europe undergo this type of lesion, which often can lead to a condition of permanent disability (Ciardelli and Chiono, 2005).
The main cause is represented by motor vehicle and sports accidents, nevertheless knives, glass, metal lacerations and bone fractures cover as much as 30% of the total cases. Even the same surgery, especially orthopedic on upper limb, it is often due to nerve injury, as they are traction maneuvers that are performed in childbirth, which cover a rate of 0.12% in all lesions (Ichiara et al , 2008).
Although surgery is a frequent medical practice in most of the cases, tissue engineering, based on knowledge and used of engineering materials, growth factors and cells (both staminal or somatic cells) is becoming more and more like a viable, and sometimes, only possibility of repair the peripheral nerve lesions (Geuna et al, 2007).
Based on these considerations it has been designed, built, developed and tested a composed tubular scaffold in polyvinyl alcohol (PVA) from chemical, physical and biological point of view. The PVA is a synthetic polymer, water-soluble, biocompatible, durable, inexpensive and hardly degradable. In order to facilitate a better kinetic of degradation of the material it has been chemically modified, by a oxidative reaction. This same reaction has been shown, moreover, to promote the release of neurotrophic factors, including TAT-CNTF, whose activity is known to be essential in the various stages of the peripheral nerves regeneration process.
The work course, from the material oxidation to the final product (through the freeze thawing technique) has developed a tubular polymer scaffold which is a patented industrial invention (No: VI2013A000019, class: A61K) deposited in “Camera di Commercio Industria, Artigianato e Agricoltura” of Vicenza, Italy
BIOMATERIALE PER DISPOSITIVI MEDICI, IN PARTICOLARE PROTESI
No full textL'invenzione riguarda un biomateriale per dispositivi medici, in particolare protesi, che comprende come base un polimero poliolico. Il biomateriale trova applicazione in dispositivi medici e come portatore di farmaco per essere applicato in sistemi di DDS (drug delivery System, sistema di rilascio di farmaci)
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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