6,769 research outputs found
Quantitative Diagnostics of Inductively-coupled Radiofrequency Plasmas in Cl<SUB>2</SUB>, O<SUB>2</SUB> and mixtures
No full textInternational audienceInductively-coupled plasmas in molecular, electronegative gases are widely used for plasma processing of surfaces, for instance in CMOS manufacture. The complexity of these systems is such that they can only be described by multi-physics models which describe both the plasma physics and the molecular collisional processes. However, there has been little rigorous validation of these models by comparison to quantitative measurements of particle densities over a wide range of parameter space. We have chosen to study the Cl2/O2 system partly because of the industrial process relevance but also because methods exist to measure the density, and energy distributions, of most of the particles present. Electron densities were measured by microwave hairpin resonator. Absolute Cl and O atom densities were determined by Two-photon Absorption Laser-Induced Fluorescence [1, 2]. We have constructed a new ultra-low noise broadband UV-visible absorption bench[3], which allows the measurement of the densities of ground state Cl2 molecules and ClxOy reaction products, as well as vibrationally excited states of O2 [3] and Cl2 [4]. Gas temperatures are determined by Doppler-resolved IR laser absorption spectroscopy of argon metastable atoms (added in small quantity), and showing that high gas temperatures (up to 2000K) can be reached. This comprehensive data set will be presented, along with comparison to different (0D and 2D cylindrical) models References [1] J.P. Booth, Y. Azamoum, N. Sirse, and P. Chabert, Journal of Physics D-Applied Physics, 45, 195201. (2012) 195201 [2] N. Sirse, J.P. Booth, P. Chabert, A. Surzhykov, and P. Indelicato, Journal of Physics D: Applied Physics, 46, (2013) 295203 [3] M. Foucher, D. Marinov, E. Carbone, P. Chabert, and J.-P. Booth, Plasma Sources Science & Technology, 24, (2015) 042001 [4] D. Marinov, M. Foucher, E. Campbell, M. Brouard, P. Chabert, and J.-P. Booth, Plasma Sources Science & Technology, in press, (2016
Prevalence and determinants of transmitted antiretroviral drug resistance in HIV1 infection
No full textTransmission of drug-resistant HIV-1 variants from antiretroviral treatment-experienced persons has been documented to occur through multiple routes, including sexual intercourse, intravenous drug use and vertically from mother to child. Newly infected persons with transmitted drug resistance (TDR) also act as a source for the onward transmission of resistant variants. Rates of virological suppression and behavioural patterns of treated populations and the relative fitness of drug-resistant variants are important determinants of the prevalence of TDR. Current estimates indicate that the prevalence is highest in regions and populations with long-established use of antiretroviral therapy. Limited data suggest that the incidence of TDR is rising in developing countries where access to therapy is increas-ing. There are methodological variations between studies, however, including those relative to the selection of the study population and the resistance interpretation system, which can skew prevalence estimates. TDR has important implications for the successful management of antiretroviral therapy. Routine resistance testing of drug-naive persons has been widely adopted in affluent countries and shown to effectively guide the selection of first-line regimens. Genotypic resistance tests offer a practi-cal approach for detecting TDR. However, routine methods can only detect resistant mutants within the dominant quasispecies and fail to detect low-frequency resistant variants, which may become important once selective drug pressure is introduced. More sensitive testing methods are being evalu-ated but remain research tools at present. In addition, factors such as superinfection and possible differences in resistance patterns between plasma and cellular reservoirs and between anatomical compartments should be considered when evaluating TDR
Does the choice of phosphate binder affect trace element levels in chronic kidney disease patients treated by regular haemodialysis?
No full textBackground. Ion exchange resins have been reported to bind copper and zinc. As the phosphate binder sevelamer hydrochloride is an ion exchange resin, we audited trace element levels in our haemodialysis cohort to determine whether sevelamer prescription affected trace element levels compared with other phosphate binders.Methods. Samples for zinc, copper and selenium were taken in special tubes and measured by atomic absorption spectroscopy or inductively coupled plasma–mass spectrometry from 211 patients attending an inner city university hospital main dialysis centre.Results. Of the patients, 12.9% were prescribed oral or intravenous trace element supplementation. Of the remainder, 5.5% of patients had low plasma copper, 37.4% low zinc and 45.6% low selenium. There was no difference in copper (16.7 ± 0.2 vs 16.8 ± 0.4 μmol/L, respectively) and zinc (12.0 ± 0.3 vs 11.6 ± 0.2 μmol/L) comparing patients prescribed sevelamer compared with other phosphate binders. Despite a high prevalence of statin prescription, total cholesterol (3.42 ± 0.12 vs 3.89 ± 0.08, P < 0.01), LDL-cholesterol (1.46 ± 0.1 vs 2.00 ± 0.07, P < 0.01) and total cholesterol/HDL-cholesterol ratio (2.82 ± 0.15 vs 3.5216.7 ± 0.2 vs 16.8 ± 0.4 μmol/L, P < 0.01) were lower in the sevelamer group compared with those prescribed other phosphate binders. On logistic regression analysis, serum zinc levels were associated with serum albumin (F 20.36, β 0.174, CL 0.086–0.265, P < 0.001) and dialysis vintage (F 8.1, β 0.008, CL 0.002–0.013, P = 0.005), copper levels with log CRP (F 31.4, β 3.04, CL 0–1.97, P < 0.001) and urine volume (F 5.1, β − 0.01, CL − 0.002–0, P = 0.024), and selenium levels with serum albumin (F 23.2, β 0.016, CL 0.02–0.1, P < 0.001) and race (F 31.4, β 3.62, P = 0.032), with selenium levels being greater in non-Caucasoids (0.9 ± 0.02 vs 0.76 ± 0.02 μmol/L, P < 0.01).Conclusions. Trace element and micronutrient deficiencies were relatively common in this inner city population of outpatient haemodialysis patients. However, the prescription of different phosphate binders did not have an observable effect on serum copper and zinc levels, but those prescribed sevelamer did have lower lipid profiles compared with those prescribed other phosphate binders. Trace element concentrations were more associated with albumin, a marker of general nutritional status, with some differences according to ethnicity, most likely due to differences in dietary intake
Open access self-archiving: An author study
No full textThis, our second author international, cross-disciplinary study on open access had 1296 respondents. Its focus was on self-archiving. Almost half (49%) of the respondent population have self-archived at least one article during the last three years. Use of institutional repositories for this purpose has doubled and usage has increased by almost 60% for subject-based repositories. Self-archiving activity is greatest amongst those who publish the largest number of papers. There is still a substantial proportion of authors unaware of the possibility of providing open access to their work by self-archiving. Of the authors who have not yet self-archived any articles, 71% remain unaware of the option. With 49% of the author population having self-archived in some way, this means that 36% of the total author population (71% of the remaining 51%), has not yet been appraised of this way of providing open access. Authors have frequently expressed reluctance to self-archive because of the perceived time required and possible technical difficulties in carrying out this activity, yet findings here show that only 20% of authors found some degree of difficulty with the first act of depositing an article in a repository, and that this dropped to 9% for subsequent deposits. Another author worry is about infringing agreed copyright agreements with publishers, yet only 10% of authors currently know of the SHERPA/RoMEO list of publisher permissions policies with respect to self-archiving, where clear guidance as to what a publisher permits is provided. Where it is not known if permission is required, however, authors are not seeking it and are self-archiving without it. Communicating their results to peers remains the primary reason for scholars publishing their work; in other words,
researchers publish to have an impact on their field. The vast majority of authors (81%) would willingly comply with a mandate from their employer or research funder to deposit copies of their articles in an institutional or subject-based repository. A further 13% would comply reluctantly; 5% would not comply with such a mandate
Progress of international hydrogen production network for the thermochemical Cu–Cl cycle
No full textThis paper presents recent advances by an international team which is developing the thermochemical copper–chlorine (Cu–Cl) cycle for hydrogen production. Development of the Cu–Cl cycle has been pursued by several countries within the framework of the Generation IV International Forum (GIF) for hydrogen production with the next generation of nuclear reactors. Due to its lower temperature requirements in comparison with other thermochemical cycles, the Cu–Cl cycle is particularly well matched with Canada's Generation IV reactor, SCWR (Super-Critical Water Reactor), as well as other heat sources such as solar energy or industrial waste heat. In this paper, recent developments of the Cu–Cl cycle are presented, specifically involving unit operation experiments, corrosion resistant materials and system integration.Atomic Energy of Canada LimitedOntario Research Excellence FundNatural Sciences and Engineering Research Council of CanadaUniversity Network of Excellence in Nuclear Engineering (UNENE)Canada Research Chairs progra
ŻYCIE UKRYTE W SŁOWIE. "BEKSIŃSCY. PORTRET PODWÓJNY" MAGDALENY GRZEBIAŁKOWSKIEJ W ŚWIETLE POSTSTRUKTURALIZMU
No full textLife Hidden in Words. Magdalena Grzebiałkowska\u27s "Beksińscy. Portret podwójny" and Poststructuralism
The article analyzes Magdalena Grzebiałkowska\u27s biographical "Beksińscy. Portret podwójny" which focuses on the lives of Zdzisław Beksiński and Tomasz Beksiński. The author looks at the construction of the biography and its relationship to poststructuralism, which allows for an appreciation of the literary features of the book. He points to how the specificity of the content, language, a mode of narration in Grzebiałkowska\u27s book make it a full-fledged literary work itself. As such the book departs from a typical biographical scheme. Juxtaposing the book with poststructural ideas leads to the reconsideration of the role of the author in the process of shaping of a biographical narrative
Systems, methods and devices for the capture and hydrogenation of carbon dioxide with thermochemical Cu—Cl and Mg—Cl—Na/K—CO2 cycles
No full textSystems, methods, and devices for producing hydrogen and capturing CO2 from emissions combine both H2 production and CO2 capture processes in forms of thermochemical cycles to produce useful products from captured CO2. The thermochemical cycles are copper-chlorine (Cu—Cl) and magnesium-chlorine-sodium/potassium cycles (Mg—Cl—Na/K—CO2). One system comprises a Cu—Cl cycle, a CO2 capture loop, and a hydrogenation cycle. Another system comprises an Mg—Cl—Na/K—CO2 cycle and a hydrogenation cycle. Devices for hydrogen production, CO2 capture, hydrogenation, and process and equipment integration include a two-stage fluidized/packed bed, hybrid two-stage spray-fluidized/packed bed reactor, a two-stage wet-mode absorber, a hybrid two-stage absorber, and a catalyst packed/fluidized bed reactor
Clean hydrogen production with the Cu–Cl cycle – Progress of international consortium, I: Experimental unit operations
No full textAdvancement of the thermochemical copper–chlorine (Cu–Cl) cycle for hydrogen production is reviewed and discussed in this paper. Individual unit operations and their linkage into an integrated cycle are being developed by a Canadian consortium, as part of the Generation IV International Forum (GIF) for hydrogen production with the next generation of nuclear reactors. This paper focuses on the consortium’s latest advances on the Cu–Cl cycle, particularly with respect to hydrogen production with Canada’s Generation IV reactor, called SCWR (Super-Critical Water Reactor). Other heat sources may also be utilized for the Cu–Cl cycle, such as solar energy or industrial waste heat. In this first of two companion papers, recent developments in Canada’s nuclear hydrogen program are reported, specifically unit operation experiments of the Cu–Cl cycle and system integration. The following second companion paper will present system modeling with Aspen Plus, corrosion resistant materials, thermochemistry, safety, and reliability aspects of the Cu–Cl cycle.Atomic Energy of Canada LimitedOntario Research Excellence FundNatural Sciences and Engineering Research Council of CanadaUniversity Network of Excellence in Nuclear Engineering (UNENE)Canada Research Chairs progra
Royal Commission on Human Relationships
No full textThis controversial Royal Commission from the 1970s found that many Australian families were failing to protect their most valuable members, and helped change the shape of public discussion around families, gender and sexuality.
This is the first time a digitised version of the Royal Commission on Human Relationships\u27 five-volume final report has been made publically available.
The Royal Commission was initiated in 1974, following a failed attempt by the Whitlam government to reform abortion law. The terms of reference were:
To inquire into and report upon the family, social, educational, legal and sexual aspects of male and female relationships, so far as those matters are relevant to the powers and functions of the Australian Parliament and Government, including powers and functions in relation to the Territories:
To give particular emphasis to the concept of responsible parenthood, to have regard to experience in other countries and to include in your inquiry the following aspects of the said matters:
(a) the extent of relevant existing education programs, including sex education programs, and their effectiveness in promoting responsible sexual behaviour and providing a sound basis in the fundamentals of male and female relationships in the Australian social environment;
(b) the extent of relevant existing programs in medical schools and their adequacy to provide comprehensive medical training in contraceptive techniques, in the physical, psychological and sexual problems experienced by women in adapting to marriage and before, during and after menstruation and in matters relating to pregnancy, fertility control, spontaneous and induced abortions and childbirth and to encourage acceptance by the medical profession of its responsibilities in the field of contraceptive counselling;
(c) the provision, adequacy and effectiveness of existing family planning facilities, educational and activational information on family planning and methods of evaluation of all family planning techniques;
(d) the social, economic, psychological and medical pressures on women in determining whether to proceed with unplanned or unwanted pregnancies, having regard to:
(i) the adequacy of housing, child-minding centres, pre-school centres, domestic assistance for families and working mothers, assistance to single parent families, other forms of assistance for mothers employed in industry, and adoption procedures;
(ii) the disabilities of families with handicapped children; and
(iii) the social status of women in the community; the social, psychological and medical results of termination of, or and failure to terminate such pregnancies;
(e) the adequacy and effectiveness of existing medico-legal determinations in relation to termination of pregnancy, the incidence of such terminations, the factors influencing their occurrence, the adequacy of medical training in an evaluation of methods of termination, consultative rights of the family or other persons concerned and the adequacy and effectiveness of pregnancy support services; and
(f) any other matters in relation to the family, social, educational, legal and sexual aspects of male and female relationships to which the attention of the Commission is directed by the Prime Minister in the course of the inquiry.
To make recommendations as to measures that are desirable with respect to the foregoing matters under existing or future laws of the Australian Parliament or of the Territories (including laws providing for grants to the States) and to indicate whether these measures should be implemented through existing bodies or through government instrumentalities to be created.
The final report, presented to Governor-General John Kerr in 1977, contained over 500 recommendations relating to "contraception (access and use), unwanted pregnancies, childbirth, attitudes to sexuality, sexual knowledge, sex education, domestic violence, rape and the police and courts’ treatment of rape victims, the changing roles of women, child care, child abuse, and homosexuality – especially discrimination faced by gays and lesbians."
The report was highly controversial when released and many of its recommendations were not acted on. However, the Royal Commission had a lasting influence. It was said to have brought taboo topics like abortion, rape and child abuse into public discussion, and to have opened up conversations about private life to this day.
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Part of the Policy History Collection. Digitisation of this report has been supported by the National Library of Australia.
Reproduced with permission of the Department of Prime Minister and Cabinet
Canada’s program on nuclear hydrogen production and the thermochemical Cu–Cl cycle
No full textThis paper presents an overview of the status of Canada’s program on nuclear hydrogen production and the thermochemical copper–chlorine (Cu–Cl) cycle. Enabling technologies for the Cu–Cl cycle are being developed by a Canadian consortium, as part of the Generation IV International Forum (GIF) for hydrogen production with the next generation of nuclear reactors. Particular emphasis in this paper is given to hydrogen production with Canada’s Super-Critical Water Reactor, SCWR. Recent advances towards an integrated lab-scale Cu–Cl cycle are discussed, including experimentation, modeling, simulation, advanced materials, thermochemistry, safety, reliability and economics. In addition, electrolysis during off-peak hours, and the processes of integrating hydrogen plants with Canada’s nuclear plants are presented.Atomic Energy of Canada LimitedOntario Research Excellence FundArgonne National Laboratory (International Nuclear Energy Research Initiative; U.S. Department of Energy)Natural Sciences and Engineering Research Council of Canada (NSERC)University Network of Excellence in Nuclear Engineering (UNENE)Canada Research Chairs (CRC
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