475 research outputs found
In the shadow of the church: the building of mosques in early medieval Syria
In his book In the Shadow of the Church: The Building of Mosques in Early Medieval Syria Mattia Guidetti examines the establishment of Muslim religious architecture within the Christian context in which it first appeared in the Syrian region, contributing to the debate on the transformation of late antique society to a Muslim one. He scrutinizes the slow process of conversion to Islam of the most important town centers by looking at religious places of both communities between the seventh and the eleventh century. The author assesses the relevancy of churches by analyzing the location of mosques and by researching phenomena of transfer of marble material from churches to mosques
Italian guidelines on thrombolysis indications in ischemic stroke have been revised after IST-3 trial and Cochrane revision: Cons
RESVERATROL-INDUCED AUTOPHAGY CONTRIBUTES TO THE INHIBITION OF EPSTEIN BARR VIRUS REPLICATION IN BURKITT’S LYMPHOMA CELLS
RESVERATROL-INDUCED AUTOPHAGY CONTRIBUTES TO THE INHIBITION OF EPSTEIN BARR VIRUS REPLICATION IN BURKITT’S LYMPHOMA CELLS
De Leo Alessandra (a), Colavita Francesca (a), Arena Giuseppe (b), Mattia Elena (a)
(a) Dip. di Scienze di Sanità Pubblica e Malattie Infettive “Sanarelli”, Univ. di Roma “Sapienza”
(b) Casa Sollievo della Sofferenza Hospital, CSS-Mendel Institute, Roma
Presenting author: De Leo Alessandra, [email protected]
We have previously examined the antiviral activity of resveratrol on the replication of Epstein Barr Virus (EBV), the etiologic agent of infectious mononucleosis and associated with several types of malignancies of epithelial and lymphoid origin.
In a cellular context that allows in vitro EBV activation and lytic cycle progression through mechanisms closely resembling those that in vivo initiate and enable productive infection, we found that RV inhibited EBV lytic genes expression and the production of viral particles in a dose-dependent manner
Does Independence Affect Regulatory Performance? The case of national competition authorities in the European Union
Despite having always been assumed to be true, a relationship between the independence of regulatory agencies and their performance has never been formally tested. This paper aims at verifying whether formal regulatory independence affects the performance of national competition authorities in the EU member states. The author presents and discusses a statistical analysis which shows that greater formal independence leads competition authorities to investigate more cases and to issue more decisions
Caterina Colombini (1304 ca.-1387) o della cugina sedotta. Una ‘ricostruzione’ della figura di Caterina attraverso i testi letterari, in Le vestigia dei gesuati. L’eredità culturale del Colombini e dei suoi seguaci, a cura di I. Gagliardi, Firenze, Firenze University Press, 2020, pp. 57-71 ISBN 978-88-5518-227-0
In this essay the author demonstrates that it is possible to reconstruct the figure of Caterina Colombini (1340?-1387) – Giovanni Colombini's cousin – through a group of texts: the hagiography of Caterina, the letters sent to her by Giovanni Colombini and, finally, Giovanni's biography written by Feo Belcari. The author divides his text into four parts: the first part analyzes the content of Caterina's hagiography; the second examines the linguistic form of the hagiographic text; in the third, the author analyzes the latent meaning of the window, a symbolic place where Giovanni and Caterina converse on divine topics; in the last part, to conclude, the teachings that Giovanni gives to Catherine and her spiritual daughters – the Gesuate – are analyzed
Diagnostic accuracy of transthoracic echocardiography to identify native valve infective endocarditis: a systematic review and meta-analysis
Infective endocarditis (IE) is a serious and potentially life-threatening disease, and accurate diagnosis is essential. We performed a systematic review and meta-analysis to assess the diagnostic accuracy of transthoracic echocardiography (TTE), with transesophageal echocardiography (TEE) as the reference standard, in patients with suspected IE of the native valves. We performed a systematic search in MEDLINE, EMBASE and Cochrane Library searching for studies that enrolled adult patients with suspected native valves IE where data about both TTE and TEE could be extracted. We included 11 studies, for a total of 2209 patients. The overall sensitivity, specificity, negative and positive likelihood ratios (LR) of TTE are 0.71 (95% CI 0.56-0.82), 0.80 (95% CI 0.58-0.92), 0.37 (95% CI 0.20-0.68) and 3.56 (95% CI 1.3-9.72), respectively. The subgroup analyses of the studies considering different cut-off levels show that the strict negative criteria (i.e., managing indeterminate results as positive) have the highest sensitivity and the lowest LR-. On the contrary, when managing indeterminate results as negative (standard criteria), the specificity and LR+ are the highest. We observed no differences between the studies performed with older and more recent technologies. In conclusion, our study results support the use of a negative TTE as a single rule-out test in patients with a low pre-test probability. In selected cases, the use of strict negative criteria might exclude IE in intermediate-risk patients, and a positive TTE might be considered as a single rule-in test with no need for TEE if TEE results would not change the patient's management
La differenza italiana e l'aporetica del "non"
In this paper, the author discuss a recent volume on Antonio
Rosmini’s thought, and in particular around the relationship
between Rosmini and Fichte and the notion of nothingness and
nothingness of love
The album of Mattia De Rossi’s drawings. Projects for the Galleria Colonna ai Santi Apostoli
The study proposed here on Mattia De Rossi, a pupil of Gian Lorenzo Bernini and his most trusted collaborator, is part of an investigation that the author is doing on the figure of the architect, making use of an obvious investigative tool: his drawings.
In particular, the exceptional discovery of a bound volume of about 200 drawings of Mattia is a resource of great effectiveness for the study of his professional figure. Among the sheets of the collection, those relating to the construction site of the Galleria Colonna in the eponymous palace in Piazza SS. Apostoli in Rome, are presented.
These drawings explain the important contribution of Mattia and the creative process that led him to the definitive version of the central hall of the gallery. The drawings are also the only graphic documents related to the project of the Galleria Colonna, now only partially known through hypothetical reconstructions.
The case of the Palazzo Colonna is similar to other projects included in the volume, which enlighten us on De Rossi's career, and which explain his position in several important Roman buildings of the second half of seventeenth centur
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