1,720,970 research outputs found
Microvascular Decompression Through Cyanoacrylate Glue-Coated Teflon Sling Transposition Technique
No full text: Vertebral artery dolichoectasia may produce a variety of clinical scenarios depending on the level of compression of several nervous structures along its course. Despite the fact that the pathophysiology is not fully clarified, it would seem that this pathologic elongation and dilation of the artery are acquired and determined by a thinning of the internal elastic lamina exposed to chronic arterial hypertension or as a result of degeneration and atherosclerosis of the arterial wall with age. When treatment is indicated, several techniques to relieve compression have been proposed, but they are usually challenging and nonstandardized. We present a case of a 78-year-old female with a 4-year history of left trigeminal neuralgia resistant to adequate dosage of multiple anticonvulsant medications and allergic to carbamazepine. She presented with a surgical history of a percutaneous microcompression of the Gasserian ganglion and 2 consecutive percutaneous radiofrequency thermorizotomies of the trigeminal nerve with transient benefit. The symptomatology was present for most of the day and impaired her quality of life, leading to severe mood decline. The patient underwent a left suboccipital retrosigmoid craniotomy (Video 1). A Teflon sling was wrapped around the vertebral artery. The 2 ends of the sling were anchored to the lateral dura by cyanoacrylate glue (Glubran 2, GEM Italy, Viareggio, Italy), pulling the vertebral artery away from the trigeminal nerve and brainstem. The patient reported complete suppression of facial pain. The case presentation, surgical anatomy, operative nuances, and postoperative course and outcome are reviewed. The patient gave written consent for participating in the procedure, surgical video, and publication of her images. Unfortunately, we did not take the picture of patient positioning for this specific case. For this reason, in order to better illustrate this surgical phase, we used the picture of another patient, who expressed her consent for publication and was operated on for a microvascular decompression with the same position as the one used for the patient described in this paper
Longitudinal, multidimensional, observational study of 15 patients with CDKL5 Deficiency Disorder
No full textBackground: CDKL5 Deficiency Disorder (CDD) is a rare developmental and epileptic encephalopathy characterized by dominant X-linked inheritance and early infantile onset. To date, more than 300 pathogenic variants of the CDKL5 gene have been reported with different phenotypes. As a rare genetic disease, data on CDD are still limited, making the diagnostic and therapeutic process very challenging. The objective of our study was to provide a comprehensive overview of CDD, including those aspects of the disease for which there is unfortunately still limited knowledge. Materials and methods: The presence of a CDKL5 variant, cognitive impairment/delayed psychomotor development, and onset of epilepsy within the first year of life were screened for the diagnosis. Comprehensive clinical assessment, laboratory and radiological investigations were performed. Results: Fifteen (n=15) patients were enrolled in the study. In most cases, concordance was found between our data and those already present in the literature. In contrast, some other features, including the development of macrocephaly and the presence of congenital gastrointestinal malformations and spinal cord abnormalities, differ from previous findings. Conclusions: Our study provides an overview on CDD, including those features for which we still have limited knowledge and, albeit on a limited sample, several insights on this rare condition
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
- …
