1,578 research outputs found
La prevenció de la violencia. L’esport com a instrument de resolució de conflictes, cohesió i convivència social entre els infants i els joves
No full textEn aquest article es recull la recerca elaborada en el marc de la Càtedra Ethos de la Universitat Ramon Llull sobre l’esport com a eina d’integració social. El fenomen de l’esport és una de les manifestacions més polièdriques de la societat contemporània que permet múltiples abordatges. En aquest article s’exposen les conclusions d’una recerca empírica que demostra com la pràctica esportiva és un poderós instrument d’integració social en el món dels joves.In this article you can read the research elaborated in the framework of the Ethos Chair of the Ramon Llull University on the sport as an instrument of social inclusion. The sport is one of the most multifaceted manifestations of contemporary society that permits multiple approaches. In this article, the author exposes the conclusions of an empirical research that demonstrates the sports practice is a power instrument of social integration in the world of youth
La prevenció de la violencia. L’esport com a instrument de resolució de conflictes, cohesió i convivència social entre els infants i els joves
No full textEn aquest article es recull la recerca elaborada en el marc de la Càtedra Ethos de la Universitat Ramon Llull sobre l’esport com a eina d’integració social. El fenomen de l’esport és una de les manifestacions més polièdriques de la societat contemporània que permet múltiples abordatges. En aquest article s’exposen les conclusions d’una recerca empírica que demostra com la pràctica esportiva és un poderós instrument d’integració social en el món dels joves.In this article you can read the research elaborated in the framework of the Ethos Chair of the Ramon Llull University on the sport as an instrument of social inclusion. The sport is one of the most multifaceted manifestations of contemporary society that permits multiple approaches. In this article, the author exposes the conclusions of an empirical research that demonstrates the sports practice is a power instrument of social integration in the world of youth
La prevenció de la violencia. L’esport com a instrument de resolució de conflictes, cohesió i convivència social entre els infants i els joves
No full textEn aquest article es recull la recerca elaborada en el marc de la Càtedra Ethos de la Universitat Ramon Llull sobre l’esport com a eina d’integració social. El fenomen de l’esport és una de les manifestacions més polièdriques de la societat contemporània que permet múltiples abordatges. En aquest article s’exposen les conclusions d’una recerca empírica que demostra com la pràctica esportiva és un poderós instrument d’integració social en el món dels joves.In this article you can read the research elaborated in the framework of the Ethos Chair of the Ramon Llull University on the sport as an instrument of social inclusion. The sport is one of the most multifaceted manifestations of contemporary society that permits multiple approaches. In this article, the author exposes the conclusions of an empirical research that demonstrates the sports practice is a power instrument of social integration in the world of youth
Raonament intel·lectual i materialitat del text: el cas de l'Ars inventiva veritatis de Ramon Llull
No full textRamon Llull's Ars inventiva veritatis (1290) is conserved in a manuscript closely connected with the author. The peculiar and complex disposition of the text of this codex permits us to study the careful organization of the work, revealing Llull's desire to guide the reader in certain specific directions. This makes evident, once again, the interrelation between the materiality and significance of the text
What Makes Help Helpful? Some Thoughts on Ethics of Solidarity Through George Orwell’s Writings
No full textOrganisations that offer personal services, whether this be
a law firm or a hospital, may be extremely good at offering technical
solutions to people, but when it comes to offering recognition, this is
much more of a challenge. These institutions often lack the ability to ‘be
respectful of each individual’.
Recognition is a central topic –often overseen– in the works of George
Orwell, the English journalist and writer who, after taking part in the
colonial system for five years, decided to ‘expiate his guilt’ by consecutively becoming homeless, taking part in agricultural labor, writing on the living conditions of the English working class and fighting as a militiaman in the Republican side during the Spanish Civil War. It was a process that spanned over several years, in which a well-educated, intellectually brilliant person, confronted and interacted with people of different countries and social backgrounds. The paper examines both failed and successful recognition experiences in Orwell’s life and work, hoping to draw some insights in how recognition works in practice.
The analysis reveals two dramatic points and leads to a pessimistic conclusion: the first point, already presented in the first part of the article, is that without recognition, no act of help will be really helpful. And secondly, real recognition only takes place between individuals. Which leads the author to conclude, confirming the initial suggestion of the paper, that full help cannot be given by any standardized procedure, and depends almost exclusively on the ability, commitment and willingness of individuals.info:eu-repo/semantics/publishedVersio
Entre vida, Ramon Llinares
No full textEntre vida, Ramon Llinares és un projecte editorial que vol ordenar, dignificar i fer visible l’arxiu fotogràfic de Ramon Llinares que recull fotografies des del 1965 fins a finals de la dècada de 1980. La feina desenvolupada consisteix en un exercici de curadoria, edició de continguts, direcció d’art, disseny gràfic i fotografia. La peça editorial es pensa com un mostrador de l’arxiu per tal de donar-li visibilitat. Vol poder funcionar com a llibre de fotografies i com a presentació de l’arxiu per ser exposat per donar valor a un autor i un material que té un paper diferenciat en el seu context.Entre vida, Ramon Llinares es un proyecto editorial que quiere ordenar, dignificar y hacer visible el archivo fotográfico de Ramon Llinares que contiene fotografías desde 1965 hasta finales de la década de 1980. El trabajo desarrollado consiste en un ejercicio de curaduría, edición de contenidos, dirección de arte, diseño gráfico y fotografía. La pieza editorial se piensa como un mostrador del archivo para darle visibilidad. Quiere poder funcionar como libro de fotografía y como presentación del archivo para ser expuesto para dar valor a un autor y a un material que tiene un paper diferenciado en su contexto.Entre vida, Ramon Llinares is an editorial project that aims to arrange, dignify and publish Ramon Llinares’ photography archive. It gathers pictures taken between 1965 and the latest 1980. The developed work consists of an exercice in curatory, content edition, art direction, graphic design and photography. The editorial piece is thought as a showcase to make the archive public. It wants to be a photography book and an archive presentation to be exposed in a gallery to value the author and his work, that had a distinct voice in its catalan photography context
The interplay of author and editor gender in acceptance delays: evidence from accounting journals
No full textThe objective of this study is to examine the impact of the gender of editors and authors, as well as their interaction, on acceptance delays (ACCDEL) of articles. We focus on genders of the corresponding author and the editor overseeing the manuscript. Using data from three top accounting journals from 2015 to 2020, we conduct a regression analysis to test the hypotheses regarding longer ACCDEL for articles under female editorship or authors, those with gender-opposite editor-author pairs, and those with coincident genders editor-author pairs. We find that when the genders of editors and corresponding authors differ, there is a significant increase in ACCDEL compared to submissions where the genders of editors and corresponding authors match. Our results suggest the existence of a prevalent gender homophily effect.info:eu-repo/semantics/publishedVersio
Biografia intel·lectual de Joan Baptista Manyà (1884-1976). Veritat i llibertat
No full textL’obra i el pensament de Joan Baptista Manyà i Alcoverro resten ignorats en la marginació de les cites col·lectives i dels clixés acadèmics. Es dona una contradicció entre la importància del personatge i l’oblit del seu pensament, al només s’al·ludeix amb obvietats i repeticions de manual. Aquest desconeixement no s’adiu amb la valoració, positiva o negativa, que després es fa del seu ideari filosòfic i teològic. En aquest sentit, Gil i Ribas considera Manyà —juntament amb Maragall, Cardó i Xiberta— com l’exponent més clar del pensament cristià de començaments del segle XX a casa nostra. El propòsit de la nostra tesi és oferir les bigues mestres de la filosofia i teologia de Manyà per llegir adequadament i contextualitzada la seva obra. Considerem que només així es pot fer un judici valoratiu acurat de l’obra manyanista, més enllà de les etiquetes empobridores i simplificadores.La obra y el pensamiento de Joan Baptista Manyà i Alcoverro restan ignorados en la marginación de las citas colectivas y los clichés académicos. Se da una contradicción entre la importancia del personaje y el olvido de su pensamiento, al cual solo se alude con obviedades y repeticiones de manual. Este desconocimiento no se aviene con la valoración, positiva o negativa, que después se hace de su ideario filosófico y teológico. En este sentido, Gil i Ribas considera Manyà —junto con Maragall, Cardón y Xiberta— como el exponente más claro del pensamiento cristiano de comienzos del siglo XX en Cataluña. El propósito de nuestra tesis es ofrecer las vigas maestras de la filosofía y teología de Manyà para leer adecuada y contextualizadamente su obra. Consideramos que solo así se puede hacer un juicio valorativo adecuado de la obra manyanista, más allá de las etiquetas empobrecedoras y simplificadoras.The work and thought of Joan Baptista Manyà i Alcoverro remain ignored in the marginalization of collective quotes and school academic clichés. There is a contradiction between the importance of the author and the oblivion of his thought, which is only alluded to with obvious and textbook repetitions. This lack of knowledge is not in keeping with the positive or negative evaluation later given to his philosophical and theological ideas. In this sense, Gil i Ribas considers Manyà —together with Maragall, Cardó and Xiberta— as the clearest exponent of the early 20th century Christian thought in our country. The purpose of this thesis is to offer the master mainstays of Manyà’s philosophy and theology to read his work properly contextualized. We believe that this is the only way to make an accurate assessment of Manyà’s work, beyond impoverishing and simplifying labels
The roles of Interferon Regulatory Factor 5 and Interleukin-1 Receptor-Associated Kinase 4 in systematic lupus erythematosus pathogenesis
No full textSystemic Lupus Erythematosus (SLE) is a polygenic autoimmune disease. Genome Wide Association Studies (GWAS) have identified Interferon Regulatory Factor 5 (IRF5) and Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) as risk loci, however prior research has failed to determine the specific cell types responsible for their roles in SLE pathogenesis or to place them in the same signaling pathway.
IRF5 is expressed in the cytoplasm of immune, muscle, fat, and liver cells. Phosphorylation of the IRF5 protein causes activation and translocation to the nucleus, where it acts as a transcription factor. Systemic knockout of IRF5 prevents development of SLE in multiple mouse models. IRAK4 is also expressed in immune cells, where it acts as both a kinase and a scaffolding protein. We hypothesized that the kinase activity of IRAK4 is required in IRF5 activating pathways in immune cells during SLE pathogenesis.
To test this, we conducted mouse bone marrow (BM) chimera studies involving the transfer of SLE-prone FcγRIIB-/-Yaa or SLE-protected FcγRIIB-/-.IRF5-/-Yaa BM cells to B6.SJL-Ptprca Pepcb/BoyJ (“CD45.1”) mice that do not develop SLE. Recipients were then examined for typical SLE markers: autoantibodies, adenopathy, splenomegaly, weight loss, and renal disease. Transfer of BM progenitors from the SLE-prone mice led to SLE in the recipients within 2-3 months of transplantation and the phenotype required IRF5 expression.
Isolating and transducing BM stem cells from the SLE-protected group with a retroviral construct before transplantation established that replacement of the IRF5 gene was sufficient to restore the SLE phenotype, even when the number of cells expressing the transgene was low (<10%). Analysis of these transgene chimeras also yielded new insights on cell specific IRF5 aspects of the disease and phenotype marker interdependencies.
Separately, we crossed FcγRIIB-/-Yaa mice with a line in which IRAK4 was modified to eliminate its kinase activity without altering its structural scaffold function. These hybrids demonstrated that IRAK4 kinase activity is required for the development of SLE and the phosphorylation of IRF5 in B cells stimulated with a Toll-like receptor 7 (TLR-7) ligand. Our combined results demonstrate that both IRAK4 kinase activity and IRF5 are required in immune cells for the development of SLE.2022-01-30T00:00:00
Mahoma y el Anticristo en la obra de Ramon Llull
No full textEl sueño de la conversión en Ramon Llull está relacionado con las vicisitudes vitales del propio autor. Así pues, la influencia islámica en el sistema luliano es obvia, además del conocimiento de fuentes árabes por parte del mismo. Por otro lado, la visión de Mahoma y el Islam que Ramon Llull presenta está íntimamente relacionada con sus planes apologéticos, insertándose en la tradición cristiana de refutación, tratando de forma tradicional un tópico como el del AnticristoThe dream of the conversion in Ramon Llull is related with the own author's vital vicissitudes. Therefore, the Islamic influence in the lulian system is obvious, besides the knowledge of Arab sources on the part of the author. On the other hand, Mohammed's vision and the Islam that Ramon Llull presents is intimately related with its apologetic plans, inserting it in the Christian tradition of rebuttal, being in to traditional way a topic like the Antichris
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