177,557 research outputs found
Dataset of mRNA levels for dopaminergic receptors, adrenoceptors and tyrosine hydroxylase in lymphocytes from subjects with clinically isolated syndromes
This data article presents a dataset of mRNA levels for dopaminergic receptors, adrenoceptors and for tyrosine hydoxylase, the rate-limiting enzyme in the synthesis of catecholamines, in peripheral blood mononuclear cells as well as in CD4+ T effector and regulatory cells from subjects with clinically isolated syndromes (CIS), which is a first episode of neurological disturbance(s) suggestive of multiple sclerosis. CIS subjects are divided into two groups according to their eventual progression, after 12 months from CIS, to clinically established multiple sclerosis. The data reported are related to the article entitled "Dopaminergic receptors and adrenoceptors in circulating lymphocytes as putative biomarkers for the early onset and progression of multiple sclerosis" (M. Cosentino, M. Zaffaroni, M. Legnaro, R. Bombelli, L. Schembri, D. Baroncini, A. Bianchi, R. Clerici, M. Guidotti, P. Banfi, G. Bono, F. Marino, 2016
Diritto e "limite": due epistemologie
Il saggio si pone le seguenti finalità: a) comprendere come il diritto si misuri, e sia destinato a misurarsi, con aree cognitive sempre più incerte e meno dominabili (con le relative proiezioni di carattere teorico-giuridico); b) soffermarsi su alcuni processi di normazione che, operando già in questa direzione, conferiscono al giurista e al teorico del diritto un ruolo ed una responsabilità cruciali anche sul piano della mediazione tra soggetti o parti sociali
Arthroplastie de hance "custom made" en issue d'osteotomie de valgus-extension selon Bombelli.
Nous rapportons un cas de l'arthroplastie de la hanche réalisée avec une prothèse "custom made" chez un patient qui avait subi il ya plusieurs années, une ostéotomie en valgus-extension selon la technique de Bombelli. Illustre la détection Tc Procédé de la forme de la tige fémorale qui est ensuite intégré à mesurer
Chomsky, linguaggio, diritto: una prospettiva neuroscientifica ante litteram?
Il saggio analizza alcuni profili della teoria linguistica di Noam Chomsky nellaquale sono rintracciabili alcune idee successivamente riprese e rielaborate in chiave neuroscientifica. Facendo riferimento a prospettive neuroscientifiche contemporanee che si ispirano espressamente a Chomsky, si considerano, in una prospettiva di "neuroscienza del diritto", alcuni riflessi che la teoria formulata dall'autore nordamericano presenta in rapporto alla sfera giuridica mostrandone taluni punti di criticità
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Is dopamine responsible for a reduction in nocturnal blood pressure fall in children with type 1 diabetes?
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
Both spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
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