86,619 research outputs found
I bolli sulle anse delle anfore Dressel 20
No full textAnalisi dei bolli su ansa delle anfore olearie Dressel 20 di provenienza spagnola, rinvenute nella discarica di una campagna di scavo alle falde del Gianicolo a Roma condotta tra il 2003 e il 2005
Cellular Senescence in Age-Related Diseases: Molecular Bases and Therapeutic Interventions
Get PDFDue to the increase in life expectancy, the aging population around the globe has been growing significantly and is estimated to triple by 2050 [...
Caratteristiche della discarica e meccanica della stratificazione. L'approccio allo scavo
No full textSono esposte le conclusioni, la metodologia e l'approccio relativi allo scavo, condotto tra 2003 e 2005 alle falde del Gianicolo a Roma per conto della Soprintendenza dei Beni Culturali di Roma
Biodegradation kinetics of 4-fluorocinnamic acid by a consortium of Arthrobacter and Ralstonia strains
Get PDFArthrobacter sp. strain G1 is able to grow on 4-fluorocinnamic acid (4-FCA) as sole carbon source. The organism converts 4-FCA into 4-fluorobenzoic acid (4-FBA) and utilizes the two-carbon side-chain for growth with some formation of 4-fluoroacetophenone as a dead-end side product. We also have isolated Ralstonia sp. strain H1, an organism that degrades 4-FBA. A consortium of strains G1 and H1 degraded 4-FCA with Monod kinetics during growth in batch and continuous cultures. Specific growth rates of strain G1 and specific degradation rates of 4-FCA were observed to follow substrate inhibition kinetics, which could be modeled using the kinetic models of Haldane–Andrew and Luong–Levenspiel. The mixed culture showed complete mineralization of 4-FCA with quantitative release of fluoride, both in batch and continuous cultures. Steady-state chemostat cultures that were exposed to shock loadings of substrate responded with rapid degradation and returned to steady-state in 10–15 h, indicating that the mixed culture provided a robust system for continuous 4-FCA degradation.
Studio dei fattori di rischio genetico nella malattia di Alzheimer: il contributo del gene codificante il recettore α (ESR1) degli estrogeni.
No full textTheoretical and experimental control strategies assessment of a Sliding Vane Oil Pump
Get PDFTo date, Sliding Vane Pump (SVP) technology is one of the most attractive solution in different technical applications thanks to its reliability and compactness and capability to keep a high efficiency even when it is working far from rated condition. In particular, this feature makes the SVP suitable to be employed for the oil circulation (SVOP) in Internal Combustion Engine (ICE) which is characterized by a wide oil flow rates variation, delivered pressure and temperature variation which causes operating conditions of the pump far from the design point. Flow delivered changes in these machines are produced by varying the eccentricity for a mechanical connection with the engine-or by varying the speed of revolution. The mild hybridization of the powertrains calls for a strong development of electrically assisted engine auxiliaries which undoubtedly makes the flow variations easier to be done, but the presence of an electric motor requires some technological choices not fully assessed, a cost increase and a reliability decrease. The paper presents a mathematical model of a SVOP for oil circulation in ICE, suitably validated by a wide experimental activity. The model integrates a mono and zero-dimensional fluid-dynamic analysis and allows to represent the intimate behaviour of the machine. Moreover, it was employed as virtual platform to discuss pros and cons of different flow rate variation strategies and their effect on the efficiency of the SVOP
The neuroanatomical substrate of lexical-semantic decline in MCI APOE epsilon 4 carriers and noncarriers
No full textLexical-semantic competency in mild cognitive impairment (MCI) epsilon 4 carriers was used as an endophenotype, and gray matter volume in MCI epsilon 4 carriers/noncarriers and in noncarrier controls was compared. Residual gray matter volumes were correlated with age of acquisition values for words from a category fluency task, an index of semantic competency. MCI patients had significantly impoverished lexical-semantic output compared with controls, more marked in MCI epsilon 4 carriers. Smaller volumes in the left hippocampus, bilateral regions of the uncus, and posterior cingulate cortex were associated with a tendency to retrieve earlier acquired words in the category fluency task in MCI epsilon 4 carriers, whereas poor semantic performance in MCI noncarriers was associated with smaller volumes in the left uncus, bilateral regions of the parahippocampal gyrus, and hippocampus, and also in a large number of neocortical regions. There was a significant semantic competency by genotype interaction in the left perirhinal cortex, in a number of left frontal and temporal areas and in the right inferior parietal lobule and precuneus. MCI epsilon 4 carriers, when compared with noncarriers, had lower gray matter volume values confined to the right precuneus and the cerebellum bilaterally, but the converse comparison showed that MCI noncarriers had lower values in extensive frontal, temporal, and parietal regions of the neocortex. Similar brain volumetric variations linked to genotype were found in minimal-to-mild AD. The results suggest a relatively specific impact of apolipoprotein E (APOE) epsilon 4 burden and underline the value of linguistic assessment in preclinical diagnosis
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Towards Sustainable High‐Performance Thermoplastics: Synthesis, Characterization, and Enzymatic Hydrolysis of Bisguaiacol‐Based Polyesters
No full textThe utilization of wood-derived building blocks (xylochemicals) to replace fossil-based precursors is an attractive research subject of modern polymer science. Here, we demonstrate that bisguaiacol (BG), a lignin-derived bisphenol analogue, can be used to prepare biobased polyesters with remarkable thermal properties. BG was treated with different activated diacids to investigate the effect of co-monomer structures on the physical properties of the products. Namely, derivatives of adipic acid, succinic acid, and 2,5-furandicarboxylic acid were used. Moreover, a terephthalic acid derivative was used for comparison purposes. The products were characterized by (HNMR)-H-1 spectroscopy, attenuated total reflectance FTIR spectroscopy, gel-permeation chromatography, thermogravimetric analysis, and differential scanning calorimetry to assess their structural and thermal properties in detail. The polymers showed glass-transition temperatures ranging up to 160 degrees C and thermal stabilities in excess of 300 degrees C. Furthermore, the susceptibility of the polyester to enzymatic hydrolysis was investigated to assess the potential for further surface functionalization and/or recycling and biodegradation. Indeed, hydrolysis with two different enzymes from the bacteria Thermobifida cellulosilytica led to the release of monomers, as quantified by HPLC. The results of this study indicate that our new polyesters represent promising renewable and biodegradable alternatives to petroleum-based polyesters currently employed in the plastics industry, specifically for applications in which high-temperature stability is essential to ensure overall system integrity
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