150 research outputs found

    Skin-friction field in turbulent convection

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    The dynamics of the boundary layers of temperature and velocity are the key to deeper understanding of turbulent transport of heat and momentum in thermal convection. Here, the structure of the skin friction field at the bottom and top plates of a Rayleigh-B\'{e}nard convection setup is investigated. We therefore analyze data obtained in direct numerical simulations of Rayleigh-B\'{e}nard convection in a cylindrical cell of aspect ratio Γ=1\Gamma = 1. Our analysis is focused to critical points of the two-dimensional skin friction field at the walls. We analyze the statistics of the critical points and relate them to the thermal plumes which detach from the wall and move up into bulk

    Modifikation des Nortropanalkaloid-Stoffwechsels in Solanum tuberosum L. durch Knockdown und Überexpression von Biosynthesegenen

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    Die Biosynthese und Funktion der zu den Nortropanalkaloiden gehörenden Calystegine sind in Solanum tuberosum (Kartoffel, Solanaceae) noch nicht vollständig aufgeklärt. Die Überexpression der Putrescin-N-methyltransferase führte zu einer Erhöhung des N-Methylputrescins der Blätter ohne Beeinflussung der Calystegine in den Keimen. Durch Fütterung von Tropinon an Pflanzen mit erhöhter und erniedrigter Expression der Tropinonreduktase I wurde die Funktion des Enzyms als Tropin-bildende Tropinonreduktase in vivo festgestellt. S. tuberosumRNA-Interferenz Pflanzen mit erniedrigter Transkriptakkumulation der Tropinonreduktase II zeigten einen stark verminderten Pseudotropin-Gehalt nach Tropinon-Fütterung der Blätter und Calystegin-Gehalt der Keime. Calystegin B2 hemmte nicht die Sporenkeimung des Oomyceten Phythophthora infestans. Durch S. tuberosum Keimextrakte wurde die Sporenkeimung nahezu vollständig gehemmt. Cucurbinsäure wurde erstmalig in S. tuberosum Blättern detektiert und quantifiziert. Mithilfe der Genomdatenbank für S. tuberosum wurden mehrere Tropinonreduktase-ähnliche Sequenzen identifiziert und hinsichtlich genomischer Struktur und Proteinsequenz analysiert.Biosynthesis and function of the nortropanealkaloidscalystegines are not completely elucidated in Solanum tuberosum (potato, Solanaceae). Overexpression of putrescine N-methyltransferase increased N-methylputrescine in leaves and did not alter calystegine accumulation in tubersprouts. Tropinone feeding on tropinone reductase I gene knockdown and overexpression plants proved that tropinone reductase I is a functional tropinone reductase in vivo. When tropinone reductase II expression was suppressed by RNA interference, pseudotropine in tropinone fedleaves and calystegine formation in tubersprouts were severely compromised. Calystegine B2did not inhibitsporegermination of theoomycetePhythophthora infestans.Extracts from tubersprouts showed a strong inhibition of P. infestans spore germination. Cucurbic acid was first detected and quantified in S. tuberosumleaves. Tropinone reduktase-like sequences were identified from theS. tuberosum genome database and analysed for genomic structure and proteine sequence.vorgelegt von Nadine Küste

    Addressing the Decline in Counseling and Supervision Process and Outcome Research in the Journal of Counseling Psychology

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    Scheel et al. have argued convincingly that there has been a decline in counseling-related research in the Journal of Counseling Psychology ( JCP) and The Counseling Psychologist ( TCP). This response focuses on the relatively steady 35-year decline in this type of research published in JCP. The author conducted a new analysis based on the frequency of PsycINFO thesaurus terms used to index 2,330 articles published in JCP over successive 5-year periods from 1975 to 2009. Results confirmed the basic conclusions of Scheel et al. that studies of the counseling and supervision process and outcome have declined over this period. Results also indicate the other types of research that have grown in frequency. These include studies of attachment behavior, multicultural issues, sexual minorities, coping, well-being, social support, and psychotherapy. The author argues that these new research areas are “counseling related” as well and that they have not crowded out the traditional studies Scheel et al. highlight. </jats:p

    Oxylipins and their involvement in plant response to biotic and abiotic stress

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    Pflanzen koordinieren ihre Reaktionen auf Bedrohungen aus ihrer Umwelt mit Hilfe eines komplexen Netzwerkes von Signalmolekülen, wobei eine wichtige Gruppe dieser Signalstoffe von Fettsäureoxidationsprodukten (Oxylipinen) gebildet wird. Mit dem Ziel neben bekannten Phytohormonen auch die Rolle anderer, oft strukturell labiler Oxylipine bei pflanzlichen Reaktionen auf biotische oder abiotische Stressfaktoren zu studieren, wurde eine schnelle und zuverlässige GC-MS-basierte Analytik entwickelt. Der Schlüsselschritt der vorgestellten Methode liegt in der in situ Derivatisierung von Oxoverbindungen mit Pentafluorbenzylhydroxylamin (PFBHA) zu stabilen Oximen bereits während der Extraktion des Blattmaterials. In den Blättern der Limabohne (Phaseolus lunatus) konnten eine Reihe von bislang unbekannten Oxylipinen identifiziert werden und durch negativ chemische Ionisationstechniken empfindlich nachgewiesen werden. Nach Schädigung kommt es zu einem starken Anstieg der Oxylipingehalte direkt in den betroffenen Blattbereichen, wobei sich das Oxylipinprofil bei Herbivorenbefall deutlich von dem nach reiner mechanischer Verletzung unterscheidet; des Weiteren konnte gezeigt werden, dass die Oxylipine des Blattes auch im Darm der fressenden Raupe auftreten und dort verändert werden, was ihre Bedeutung als Signalstoffe auch für die Raupe nahe legt

    The Ghosts of Counseling Psychology: Is Counseling Research Really Dead?

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    Scheel et al. offer an interesting analysis on the publication rate of counseling-related research articles in counseling psychology’s two major journals. In this reaction to their work, the author considers various aspects of their results and contemplates possible explanations for the decline of counseling-related publications. </jats:p

    Sustainable transformation of cities: The case of Eindhoven, the Netherlands

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    The question of sustainable urban development is linked to the issue of urban transformation; the challenge is to make use of ongoing transformation processes to achieve more sustainable urban environments. Hildebrand Frey is the main protagonist of the \u93urban cell theory\u94 (UCT), focused on the redesign of existing cities, laying down important arguments for neighborhood borders and centers. For decisions to pursue the sustainability path, the pragmatic method will be a practical tool in bringing sustainable considerations in the realm of project decisions. This paper examines the sustainable transformation of cities upon a re-mapping of the existing city to identify the potential urban cells, restructuring of the actual city of districts and neighborhoods; focused on Eindhoven as a case study, specifically the District of Woensel, describing the operationalization of the UCT as a conceptual framework. This work is structured in three parts: 1- a preliminary analysis identifying the existing neighborhoods in the district to analyze how the existing parts of the city meet the criteria of UCT; 2- the description of how to join non-potential and potential sustainable areas of the existing city to create \u93large units\u94 of the city; 3- The elaboration of results indicates that all the parts of the city are part of potential sustainable areas, obtaining hence a principal layer of the map of the sustainable city. The relevance of this approach is to contribute new insights to the debate of sustainable city borders

    Simulating and classifying large-scale spatial sand-mud segregation using a process-based model for a tidal inlet system

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    Tidal inlet systems, as found in the Dutch Wadden Sea, often feature both sand and mud. Due to differences in sediment properties, sand and mud particles respond different to identical forcing conditions, like short waves and tidal currents. Because of this, sand and mud can get transported to different locations. This process is referred to by sand-mud segregation. Sand-mud segregation can have considerable influences on bathymetry, potential pollution and flora & fauna. It is because of these aspects that predictions on sand-mud segregation are needed. To predict sand-mud segregation, commonly for a practical scenario, a morphodynamic model can be used. Though, modelling a practical scenario often comprises a complex bathymetry and various non-linear processes, that contribute to sand-mud segregation, occur. Because of this, practical sand-mud segregation models are often hard to understand, give little insight in the overall processes and discrepancies with reality are often found within the results. These problems can be overcome by considering a schematized scenario, where only the overall forcing conditions (tidal currents and short waves) are considered, along with a schematized bathymetry and geometry. By considering a schematized scenario of the Amelander tidal inlet system, the large-scale sand-mud segregation patterns can be reproduced. It is found, e.g. in observations from the field and theoretical descriptions, that mud is commonly found in less hydrodynamic active areas (as long as mud is available). Within the Amelander tidal inlet system, mud is therefore found in the shallow intertidal areas, far from the deeper hydrodynamically active areas, like the tidal inlet and tidal channels. The schematized process-based model (a newly developed sand-mud version of Delft3D, which accounts for (non) cohesive regimes, a layered stratigraphy and consolidation lag) also reproduces these large-scale spatial sand-mud segregation patterns, with the schematized process-based approach. By combining the schematized model approach with variations in relative forcing domination (by tidal currents or short waves), various scenarios can be considered. From observations in the field and associated sand-mud segregation theory, one always expects mud deposition in less hydrodynamically active areas. Given the properties of tidal currents and short waves, it is hypothesized that mud is commonly found in deeper/shallow areas, respectively for a relative dominance of tidal currents/short waves. Results from the schematized process-based model support this hypothesis. Mud is transported to deeper areas when short wave domination is imposed, while mud is commonly found in shallow areas for a tidally dominated system. A schematized process-based sand-mud segregation model is able to reproduce large-scale spatial sand-mud segregation patterns for a practical case (the Amelander tidal inlet system). Furthermore, a classification can be set up, relating these large-scale spatial sand-mud segregation patterns to relative forcing dominance (from tidal currents or short waves), which is based on observations, theory and the schematized process-based model.Coastal EngineeringHydraulic EngineeringCivil Engineering and Geoscience

    Silencing of GATA3 defines a novel stem cell-like subgroup of ETP-ALL

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    This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.This work was supported by a research grant from the Deutsche Krebshilfe (Mildred Scheel Professur) and the Wilhelm Sander-Stiftung to CD Baldu

    HOT decommissioning guidance for homeowners

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    Title from PDF cover (viewed on January 8, 2020)."DEQ 12-LQ-033."Covers OCLC #1135332256 and OCLC #918871621.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references.Mode of access: Internet from the Oregon Government Publications Collection.Text in English

    HOT cleanup guidance for homeowners

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    Title from PDF cover (viewed on January 8, 2020).Covers OCLC #1135332317 and OCLC #918871622.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
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