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Valvuloplastica con palloncino ecoguidata in un cane affetto da stenosi polmonare.
An Italian hound dog, female, 2 years old, with pulmonic valve stenosis was
treated by balloon valvuloplasty. Transthoracic echocardiographic examination was carried out
to make the diagnosis, to determine pulmonic annulus size, to calculate the dimensions of the
balloon required for the treatment and to make a Doppler study of the trans-pulmonic blood
flow before and after the balloon dilatation. Echocardiography was carried out also to evaluate
the possibility to perform valvuloplasty in veterinary medicine solely under a non-invasive
guidance and not under fluoroscopy, similarly to that was already observed in human medicine
Left-sided congestive heart failure in a dog with intraventricular rhabdomyosarcoma
CASE REPORT A 9-year-old female Labrador Retriever was referred for evaluation of a 7-day history of exercise intolerance and dyspnoea. Thoracic radiographs showed moderate left atrial enlargement and severe pulmonary oedema. Transthoracic echocardiography revealed a heterogeneous hyperechoic mass extending from the left inflow tract to the outflow tract and protruding through the aortic ostium during systole. Spectral Doppler echocardiography was consistent with left ventricular inflow and outflow tract obstruction secondary to the mass. Because of the lack of response to treatment and the poor prognosis, the dog was euthanased and necropsy was performed. A large intracavitary mass, originating from the left ventricular free wall, filled the ventricular cavity. Mitral leaflets were distorted and thickened with shortened chordae. Microscopic findings were consistent with a rhabdomyosarcoma. CONCLUSION This report describes an intracavitary left ventricular rhabdomyosarcoma in a dog, causing left ventricle outflow tract obstruction and functional mitral stenosis that was clinically associated with pulmonary oedema
Validation of a Wearable System for Respiratory Rate Monitoring in Dogs
One of the most relevant physiological parameters in dogs is respiratory rate (RR). The aim of this paper is to present a novel wearable system that allows to accurately estimate RR in dogs, and to compare it to a gold standard in static conditions. Data from 12 dogs were acquired while the animals were anesthetized and attached to a vital signs monitor. The experimental setup consisted of three Inertial Measurement Units (IMUs) applied on the dog, and a video camera filming the RR value shown on the monitor. The range of RR values analyzed in the study is 0 to 29 breaths per minute, read by the vital signs monitor. The mean RMSE for the data acquisitions is 1.68 breaths per minute. The values of the filtering parameters that allow to obtain the best performance depend on the specific acquisition. This result demonstrates that adaptive filtering is a viable method for the application. Future developments include tests on a larger dataset, and trials on dogs in unconstrained environments and during movement
Ketamine as a part of anaesthetic management in a dog with twiddler's syndrome
An 11-year-old male German shepherd dog was referred for possible pacemaker implantation. A routine 6-lead electrocardiogram revealed a third-degree atrio-ventricular block with a heart rate of 40 to 45beats/minute. A transvenous pacemaker implantation procedure was scheduled. The dog was premedicated with 10 μg/kg acepromazine and 5 mg/kg pethidine. A dose of 5 mg/kg ketamine and 0·2mg/kg diazepam were used for induction and isoflurane in O2 and a constant rate infusion of ketamine (20 to 30 μg/kg/minute) were administered for maintenance of general anaesthesia. Due to a twiddler's syndrome, the pacemaker had to be repositioned. For the second procedure, the same protocol was employed except for a lower dose of ketamine both for induction (3 mg/kg) and constant rate infusion (10 to 15 μg/kg/minute). Ketamine appeared to be useful for both management of anaesthesia and cardiac pacemaker implantation in the absence of a temporary pacemake
Management of re-stenosis following balloon catheter dilation of cor triatriatum dexter in a dog
A 10-month-old male American Pitbull Terrier puppy was treated for the correction of cor triatriatum dexter by balloon catheter dilation under echocardiographic guidance. Two weeks after the interventional procedure, the dog presented ascites because re-stenosis of cor triatriatum dexter occurred. A second interventional procedure, by combining membranostomy and balloon catheter dilation of the intra-atrial septum, allowed the resolution of congestive heart failure. Based on the clinical outcome, the alternative approach described in this report appears to be a viable treatment option for dogs affected with cor triatriatum dexter, especially when re-stenosis occurs
Impiego di flecainide nel trattamento della fibrillazione striale cronica nel cavallo: osservazioni personali
Insufficienze valvolari nel cavallo: casistica personale (2005-2011).
Introduzione e scopo - Le patologie cardiache
acquisite più comuni nel cavallo sono le insufficienze
valvolari che possono essere individuate
sia nei soggetti giovani che anziani. Lo scopo di
questo studio retrospettivo è quello di valutare
la prevalenza delle diverse patologie valvolari in
cavalli riferiti al Dipartimento di Clinica Veterinaria,
Facoltà di Medicina Veterinaria di Pisa, a causa
di scarso rendimento atletico/intolleranza all’esercizio,
negli anni 2005-2011.
Materiali e metodi - In questo studio retrospettivo
sono stati analizzati i dati relativi alle
visite cardiologiche effettuate su 79 cavalli adulti.
Tutti i soggetti sono stati sottoposti a esame
obiettivo generale e particolare dell’apparato
cardiocircolatorio, elettrocardiogramma ed
ecocardiografia. Su alcuni cavalli è stato registrato
anche l’elettrocardiogramma sotto sforzo.
L’ecocardiografia Doppler effettuata in tutti
i soggetti ha permesso di valutare i flussi
transvalvolari al fine di evidenziare la presenza
di insufficienze delle valvole cardiache.
Risultati - Dei 79 cavalli esaminati, l’81% non
erano affetti da patologie cardiocircolatorie. In
15/79 (19%) soggetti sono state diagnosticate
patologie cardiache funzionali e/o alterazioni
morfologiche. Due dei 79 cavalli (2,5%) presentavano
patologie cardiache non valvolari. Dei
13 cavalli con insufficienze valvolari 1/79 (1,3%)
presentava insufficienza mitralica (IM), 3/79
(3,8%) insufficienza aortica (IA), 2/79 (2,5%) insufficienza
tricuspidale (IT), 1/79 (1,3%) IM e IA,
2/79 (2,5%) IM e IT, 1/79 (1,3%) IA e IT, 1/79
(1,3%) IM e insufficienza polmonare (IP), 1/79
(1,3%) IM, IA e IP, 1/79 (1,3%) IM, IA e IT.
Conclusioni - Le insufficienze valvolari rappresentano
le patologie cardiache acquisite più
comuni nel cavallo. Nei 13 soggetti affetti da patologie
valvolari cardiache, è stato possibile diagnosticare
7 IA (31,8%), 7 IM (31,8%), 6 IT (27,3%)
e 2 IP (9,1%). Possiamo pertanto concludere
che, l’IM e l’IA risultano essere le patologie valvolari
di più frequente riscontro, mentre l’IT e
l’IP risultano reperti occasional
Treatment of chronic atril fibrillation in the horse with flecainide: personal observation.
Atrial fibrillation is a disturbance of the cardiac rhythm associated with poor perfor- mance in athletic horses. Quinidine is the drug of choice for restoring sinus rhythm in horses because of its high success rate (85%) in cases with no anatomical lesions of the atrial myocardium. However, side effects and adverse effects are commonly reported with quinidine cardioversion. Nose-gastric administration is frequently associated with nasal mucosal edema, urticaria, paraphymosis, hypotension, colic and diarrhea. Further- more, proarrhythmic effects of quinidine can induce rapid ventricular tachycardia (Btorsade des pointes^) and sudden death. Therefore, pharmaceutical alternatives to quinidine, with less side effects and similar efficacy, would be desirable. Flecainide has been found to be well tolerated and easy to administer and preliminary studies in horses with induced AF and acute AF suggested that it is effective in restoring sinus rhythm (Ohmura et al., 2000, 2001). Flecainide is an antyarrhythmic agent of Vaughan- Williams class IC which strictly binds to and blocks the fast Na-channel, decreasing maximum velocity of depolarization during phase 0 and prolonging the action potentials in the atrial and ventricular myocardium and in the Purkinje fibers. This results in slow- ing of the conduction through these structures, particularly within the His-Purkinje sys- tem. Electrocardiographically the P-R interval and the QRS duration prolong, as does the Q-T interval, even though shortening of the J-T interval (from the end of the QRS to the end of the T wave) is commonly seen. A recent clinical study of 10 horses with natural occurring AF treated with flecainide found that just one horse converted to sinus rhythm, while the remainder were cardioverted using the Bclassical^ quinidine protocol
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274
(Van Loon et al., 2004). The aim of the present study was to focus on the effectiveness and safety of flecainide in horses with chronic atrial fibrillation that were not amenable to quinidine cardioversion
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