197 research outputs found

    Molecular and cellular determinants of cardiac tachyarrhythmias: from trigger to therapy

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    Cardiac tachyarrhythmias are a vast contributor to morbidity and mortality worldwide. Still, the mechanisms underlying these arrhythmias are incompletely understood. As a result, many of the treatment options available for these arrhythmias rely on sole alleviation of symptoms or prevention of complications secondary to the arrhythmia, or are associated with non-trivial adverse effects. An increased understanding of the mechanisms underlying cardiac tachyarrhythmias as well as the means to reverse them is a critical prerequisite if we are to shift towards more specific, more effective and less harmful arrhythmia treatment. Therefore, the research described in this thesis investigates the molecular and cellular determinants of cardiac tachyarrhythmias in ex vivo and in vitro models of cardiac hypertropfy/fibrosis, ventricular fibrillation and atrial fibrillation using state of the art electrophysiological and genetic tools

    Verkeerswaterbouwkunde b.o.

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    Vaartuigen, vaarwegen, vaarweggebruikers, prognoses van het scheepvaartverkeer, begrippen capaciteit en weerstand, dimensionering van schutsluizen, capaciteit en weerstand van schutsluizen.Hydraulic EngineeringCivil Engineering and Geoscience

    Waterbouwkundige kunstwerken b.o. (tunnels)

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    Soorten oeververbindingen, afweging van keuzes, lengteprofiel van een tunnel, dwarsprofiel van een tunnel, uitvoering van het gezonken deel, enige constructieve aspecten.Hydraulic EngineeringCivil Engineering and Geoscience

    Waterbouwkundige kunstwerken B.O.: Voorlopig dicaat

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    Civil Engineering and GeosciencesHydraulic Engineerin

    General B.O. Smith with four unidentified men.

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    https://egrove.olemiss.edu/cfclayton/1058/thumbnail.jp

    Aspecten van zandtransport in open waterlopen

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    College "Materiaaltransport B.O.", sedimenttransport in rivieren.Hydraulic EngineeringCivil Engineering and Geoscience

    Waterbouwkundige constructies b.o. I, college f9A

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    Hydraulic EngineeringCivil Engineering and Geoscience

    Comparing Ochiai and Relief for Spectrum-based Fault Localization

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    Fault localization is one of the activities of system diagnosis and its goal is to pinpoint the precise locations of faults in systems. This process is recognized as one of the most tedious, time-consuming and expensive undertakings of fault diagnosis. Consequently research in this domain have lead to the birth of numerous approaches to automate the process in order to minimize failures and produce reliable systems. Among the proposed fault localization approaches are the statistical-based Spectrum-based Fault Localization (SFL) and machine learning based Feature Selection Relief. In SFL, the assumed faultiness of a system component is computed using a similarity coefficient and the most commonly used coefficients are Ochiai, Tarantula and Jaccard. Currently, Ochiai clearly outperforms most of the known similarity coefficients in SFL. The Feature Selection based Relief, in short known as Relief, is an alternative technique that has been recently proposed for fault localization. The Relief technique works by assigning relevance weights to components and the components that are likely to be faulty receive the highest relevance weights. In this document, we describe the study performed to compare the performance of Ochiai and Relief for SFL in various systems using the SFL-Simulator which is a Ruby-based tool used for research in SFL. Results from the study indicate that the diagnostic performance of both fault localization methods largely depends on the configuration of the system under investigation, i.e. the number of faults, the health states of the faulty components, the constituent components and the links between them and the number of transactions or test runs used. Furthermore, the study has shown that Ochiai has a computational complexity that is superior to Relief.Software EngineeringSoftware and Computer TechnologyElectrical Engineering, Mathematics and Computer Scienc

    Clause F. Clayton with Turnage, General B.O. Smith, and Lt. Col. L.C. Ator.

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    1960-1969https://egrove.olemiss.edu/cfclayton/1123/thumbnail.jp

    КУЛЬТУРНО-МИСТЕЦЬКІ ПРОГРАМИ: ОСНОВИ ВИХОВНОЇ ТЕХНОЛОГИ І ПІДГОТОВКА ВЧИТЕЛІВ МИСТЕЦЬКИХ ДИСЦИПЛІН ДО ї ї РЕАЛІЗАЦІЇ У ШКОЛІ

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    In the article are examined the substantive conceptual positions of the author educating technology «Cultural and art programs». Author lights theoretical, methodical and organizational national aspects of preparation teachers of artistic disciplines to the mastering of this technology
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