1,721,848 research outputs found
Le charme de Tian Hou [Par delà le registre culturel]
No full textBing Cheng Christina Miu, Cowen Sarah. Le charme de Tian Hou [Par delà le registre culturel]. In: Perspectives chinoises, n°55, 1999. pp. 72-81
Systematic Review and Meta-analysis Tutorial for Effects of Talker Variability in Speech Training
No full textOriginal data and codes for the manuscript entitled "The Role of Talker Variability in Non-native Phonetic Learning: A Systematic Review and Meta-analysis". Correspondence: [email protected] [email protected]
Authors: Xiaojuan Zhang, Bing Cheng, Yang Zhan
Systematic Review and Meta-analysis Tutorial for Effects of Talker Variability in Speech Training
No full textOriginal data and codes for the manuscript entitled "The Role of Talker Variability in Non-native Phonetic Learning: A Systematic Review and Meta-analysis". Correspondence: [email protected] [email protected]
Authors: Xiaojuan Zhang, Bing Cheng, Yang Zhan
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Abstract 3454: Autophagy governs tumorigenic effects following mitotic slippage
No full textAbstract
Antimitotic drugs are often administered as first-line chemotherapy in several malignancies. However, their clinical success is often limited by acquired chemoresistance and disease relapse. The anti-proliferative basis of these drugs is induction of mitotic arrest culminating in cell death. Mitotic slippage occurs when cells exit mitosis and “slip” into interphase without chromosome segregation and cytokinesis. Little is known about how cells post-slippage influence outcome of treatment. Here, we demonstrate that post-slippage cells exhibit paracrine pro-tumourigenic potential following senescence and senescence-associated secretory phenotype development. This occurs in an autophagy-p53 axis-dependent manner, with autophagic inhibition in post-slippage cells bypassing senescence and leading to cell death. Indeed, the autophagy inhibitor Chloroquine and microtubule poisons synergistically inhibited tumour growth in mice. Hence, regimens targeting the senescence phenotype could provide a potential effective combinatorial strategy with antimitotic drugs. Sensitivity to this combinatorial treatment was dependent on p53 status, an important factor to consider before treatment.
Citation Format: Karen C. Crasta, Bing Cheng, Ke Guo. Autophagy governs tumorigenic effects following mitotic slippage [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 3454. doi:10.1158/1538-7445.AM2017-3454</jats:p
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