11 research outputs found
Business Intelligence in Strategic Management: Study of automation modifying the strategy of business
No full textThe core aim of this thesis was to provide better knowledge of business intelligence and how it has changed the style of business. The objective of this thesis was studying the need for technology in the business environment and how businesses can utilize technologies to gain profit. The purpose of this study was to understand the need for business intelligence in the present business market. Exploratory research was chosen to support this thesis. This thesis was done to get the idea of business intelligence and its tools and in what ways those tools can be used in the decision-making process. The motive of this thesis was to find the linkage between business intelligence and strategic management.
The theoretical framework of this thesis discussed the preface of business intelligence and its components, history, analysis, and adoption of business intelligence globally. In this thesis, the author discussed the role of business intelligence in the decision-making process and strategic management. Moreover, the author explored the impact of business intelligence and its use. The target of this thesis was learning about business intelligence and its present trends.
The results of this thesis provided how business intelligence can help in the decision-making process in businesses and how implementing business intelligence will enhance the performance of the organization. Moreover, the results discussed the utilization of business intelligence in strategic management and what benefits a company can get. Business intelligence has affected the business world. Many organizations have adopted it and other organizations will adopt it too in the future
Formulation and Characterization of Alginate Dialdehyde, Gelatin and Platelet Rich Plasma Based Bioink for Bioprinting
No full textLayer-by-layer additive manufacturing process has evolved into three-dimensional (3D) “bio-printing” as a means of constructing cell-laden functional tissue equivalents. The process typically involves the mixing of cells of interest with an appropriate hydrogel, termed as “bioink”, followed by printing and tissue maturation. An ideal bioink should have adequate mechanical, rheological, and biological features of the target tissues. However, native extracellular matrix (ECM) is made of an intricate milieu of soluble and non-soluble extracellular factors, and mimicking such a composition is challenging. To this end, here we report the formulation of a multi-component bioink composed of gelatin and alginate -based scaffolding material, as well as a platelet-rich plasma (PRP) suspension, which mimics the insoluble and soluble factors of native ECM respectively. Briefly, sodium alginate was subjected to controlled oxidation to yield alginate dialdehyde (ADA), and was mixed with gelatin and PRP in various volume ratios in the presence of borax. The formulation was systematically characterized for its gelation time, swelling, and water uptake, as well as its morphological, chemical, and rheological properties; furthermore, blood- and cytocompatibility were assessed as per ISO 10993 (International Organization for Standardization). Printability, shape fidelity, and cell-laden printing was evaluated using the RegenHU 3D Discovery bioprinter. The results indicated the successful development of ADA–gelatin–PRP based bioink for 3D bioprinting and biofabrication application
Formulation and Characterization of Alginate Dialdehyde, Gelatin, and Platelet-Rich Plasma-Based Bioink for Bioprinting Applications
No full textLayer-by-layer additive manufacturing process has evolved into three-dimensional (3D) “bio-printing” as a means of constructing cell-laden functional tissue equivalents. The process typically involves the mixing of cells of interest with an appropriate hydrogel, termed as “bioink”, followed by printing and tissue maturation. An ideal bioink should have adequate mechanical, rheological, and biological features of the target tissues. However, native extracellular matrix (ECM) is made of an intricate milieu of soluble and non-soluble extracellular factors, and mimicking such a composition is challenging. To this end, here we report the formulation of a multi-component bioink composed of gelatin and alginate -based scaffolding material, as well as a platelet-rich plasma (PRP) suspension, which mimics the insoluble and soluble factors of native ECM respectively. Briefly, sodium alginate was subjected to controlled oxidation to yield alginate dialdehyde (ADA), and was mixed with gelatin and PRP in various volume ratios in the presence of borax. The formulation was systematically characterized for its gelation time, swelling, and water uptake, as well as its morphological, chemical, and rheological properties; furthermore, blood- and cytocompatibility were assessed as per ISO 10993 (International Organization for Standardization). Printability, shape fidelity, and cell-laden printing was evaluated using the RegenHU 3D Discovery bioprinter. The results indicated the successful development of ADA–gelatin–PRP based bioink for 3D bioprinting and biofabrication applications
An explicit correlation between surface functionality, wettability, and leukocyte removal by electrospun filter media
No full textScaffold for liver tissue engineering: Exploring the potential of fibrin incorporated alginate dialdehyde–gelatin hydrogel
No full textAqueous based synthesis of CdSe/ZnS Q-dots: Study on luminescence properties and cytotoxicity
No full textPresent study aims to modify the thioacid capped CdSe Quantum-dots (Q-dots) surface by ZnS coating by direct synthesis in aqueous medium. CS formation was confirmed by red shift as well as enhancement in the luminescence peak compared to bare Q-dots. Effects of processing parameters during the shell preparation such as core concentration and sulphur concentration on the luminescence properties of CS have been studied. Processing parameters have been optimized at maximum luminescence efficiency. Cytocompatibility behavior was found to be better for CS compared to their bare Q-dots counterpart after evaluation. Cytotoxicity of CS has been further evaluated by changing the sulphur concentration and after aging for 8 days
DEAE- Cellulose-based composite hydrogel for 3D printing application: Physicochemical, mechanical, and biological optimization
No full text3D bioprinting is a layer-by-layer additive manufacturing process that requires the incorporation of biomaterials, cells, growth factors, etc. The biomaterial-ink used in bioprinting should comprise essential properties like shear thinning, proper viscosity and reduced shear stress on cells, structural integrity, porosity, biocompatible and degradable, etc., Especially in extrusion-based bioprinting, optimization of biomaterial ink is critical. Even though single-aspect biomaterials have been used for establishing a biomaterial ink, however, they often fail to meet all properties needed to be used as a biomaterial ink. Carrying this point in view, we have formulated hydrogels using Diethylaminoethyl Cellulose (DEAE-Cellulose), Alginate (ALG), and Gelatin (GEL) as biomaterial inks. Initially, six different hydrogel formulations (F1-F6) were prepared with varying concentrations of DEAE-Cellulose (0.45%-2%), alginate (1%-2%), and keeping gelatine concentration constant at 3.33%. These for-mulations were then assayed by swelling and degradation tests. Out of six, three hydrogels (F3, F4, and F5) were eliminated after initial studies due to the rapid degradation rate. The other three hydrogels ( F1, F2, and F6) were further thoroughly analyzed by the rheological study, mechanical study, printability assay, morphological analysis, and biocompatibility assays. Here, We have demonstrated the successful formulation of three bioma-terial inks utilizing three different biopolymers for the field of tissue engineering with adequate swelling, degradation, rheological and printability properties. It was observed that the incorporation of DEAE-Cellulose significantly improved the shear thinning and viscosity recovery of hydrogels. Also, it improves mechanical integrity and printing accuracy. Moreover, all three hydrogels have shown excellent hemocompatibility and cytocompatibility. To conclude, this study proposes the optimization of composite hydrogel for 3D printing applications
Biofunctionalised polycaprolactone fibrous mat as a transfer tool for cell sheet engineering
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